Piezoelectric composite dressing for promoting peripheral nerve repair and wound healing and loading exosome of traditional Chinese medicine and preparation method

A technology for wound healing and peripheral nerves, applied in the fields of medical formula, medical science, drug delivery, etc., can solve problems such as difficult to achieve therapeutic effect, blank, etc., achieve broad medical and commercial prospects, promote proliferation, and promote wound healing.
CN110464867AActive Publication Date: 2019-11-19ZHEJIANG UNIV
5 Cites 17 Cited by

Patent Information

Authority / Receiving Office
CN · China
Current Assignee / Owner
ZHEJIANG UNIV
Publication Date
2019-11-19

Smart Images

  • Figure 1
    Figure 1
  • Figure 2
    Figure 2
  • Figure 3
    Figure 3
Patent Text Reader

Abstract

The invention provides a piezoelectric composite dressing for promoting peripheral nerve repair and wound healing and loading exosome of traditional Chinese medicine and a preparation method. The preparation method comprises the following steps that gelatin and methacrylic anhydride react to prepare methacrylate gelatin; the exosome of the Chinese medicine is prepared through differential centrifugation;a conductive pregel system is prepared through the recombination of gold nanorods, the exosome and the methacrylate gelatin; and the conductive pregel and a polyvinylidene fluoride ethylene piezoelectric thin film arerecombined, and the piezoelectric composite dressing is prepared. The dressing prepared by the preparation method is a novel dressing for piezoelectric stimulation composite medicine action, polyvinylidene fluoride ethylene produces electricity potential to stimulate a wound area through the conductive gel, wound healing and nerve regeneration are promoted with the exosomeof the traditional Chinese medicine, and the problems in the current wound repair and nerve repair process can be effectively solved. Therefore, the composite dressing has a wide application value inthe treatment of trauma and nerve repair.
Need to check novelty before this filing date? Find Prior Art

Description

technical field

[0001] The invention relates to a piezoelectric composite dressing that promotes peripheral nerve repair and wound healing and loads traditional Chinese medicine exosomes and a preparation method. Background technique

[0002] The skin is the first line of defense of the human body and is also the largest organ of the human body. It has multiple functions such as sensation and protection. However, in daily life, the skin is often affected by various external factors, which often cause trauma and bring heavy pressure and burden to individuals and society. However, wound healing is a complex and dynamic process, including a variety of tissues and cells involved in the regulation. However, the uncontrolled adjustment of the wound repair process leads to serious scars after wound healing, and the inability to regenerate appendages, resulting in repair obstacles. At the same time, a complex neural network is also distributed on the surface of the skin, mainly in...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More