Magnesium alloy bone nail and preparation method and application thereof

Abstract

The invention provides a magnesium alloy bone nail and a preparation method and application thereof. The preparation method comprises the following steps: carrying out hot extrusion treatment on a magnesium alloy cast ingot to obtain a magnesium alloy round bar, and carrying out drawing treatment and heat treatment to obtain a first magnesium alloy thin round bar and a second magnesium alloy thinround bar; forming first cavity and a second cavity communicated with the first cavity sequentially in the first magnesium alloy thin round bar in the length direction of the first magnesium alloy thin round bar, and obtaining a first magnesium alloy bone nail, wherein one side, deviating from the first cavity, of the second cavity is closed; and processing the second magnesium alloy thin round bar to obtain a second magnesium alloy bone nail, forming porous ceramic layers on the surfaces of the first magnesium alloy bone nail and the second magnesium alloy bone nail, and forming a microporouspolymer layer on the overall surface of the two magnesium alloy bone nails to obtain the magnesium alloy bone nail. The degradation rate of the bone nail is slowed down and controllable through the porous ceramic layer, and medicine can be injected into the second cavity and slowly released through the microporous polymer layer.

Description

technical field [0001] The invention belongs to the technical field of medical devices, and in particular relates to a magnesium alloy bone nail, a preparation method of the magnesium alloy bone nail, and an application of the magnesium alloy bone nail. Background technique [0002] At present, in surgical operations, bone nails are one of the commonly used medical devices in bone repair operations. Traditional bone nails are mainly made of titanium alloy and stainless steel. These materials have good mechanical properties and corrosion resistance, but their elastic modulus is high, and there is an obvious stress shielding effect after implantation. In addition, the patient’s bone tissue needs two weeks of healing after healing. It is removed in a second operation, which will not only cause a physical burden on the patient, but also easily cause secondary infection. [0003] The magnesium alloy material has good mechanical properties, and the elastic modulus is close to tha...

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Problems solved by technology

Among them, the Chinese patent CN106377803B, one of the existing technologies, designed an alloy composition. Through powder metallurgy and machining, a magnesium alloy with excellent mechanical properties and corrosion resistance was obtained, but the impact of some elements on the human body is still unclear.

[0005] In addition, Chinese patent application CN109432514A, one of the existing technologies, proposes a method of micro-arc oxidation to obtain a layer of scaly bone-like nanostructure bio-coating on the surface of the substrate. The coating has antibacterial, osteogenic and favorable cell adhesion However, the matrix composition of its magnesium alloy is AZ series alloy, and the Al element has adverse effects on human health

[0006] Chinese patent CN104623739B, one of the existing technologies, designs an alloy composition, and obtains a magnesium alloy bone nail or bone plate through smelting, extrusion, aging and machining, and then obtains a fluoride layer and a calcium-phosphorus layer through surface treatment, which has the same properties as The new bone growth rate is comparable to the matching degradation rate, but the influence of some elements is also unclear, and there is no functional effect

[0007] Therefore, although the degradable bone nails in the prior art have a drug-loading function, they cannot customize the type and dose of drugs according to the patient's condition, and cannot meet the needs of all patients. Magnesium Alloy Nails

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