Probiotic preparation capable of relieving acute alcoholism, and preparation method and application thereof

A technology of probiotic preparations and alcoholism, applied in the field of probiotics, can solve the problems of lack of prebiotics and vitamins, ineffective effect, short survival time of probiotics, etc., achieve strong practicability, shorten sleep time, and be suitable for large-scale production Effect

Inactive Publication Date: 2020-06-19
合肥微崇生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] At present, there are related technologies in China. Two patents, CN201110432768.2 and CN201210005581.9, both involve a liquid drink. The disadvantage is that the survival time of probiotics in the liquid is relatively short, and there is a lack of prebiotics and vitamins. The effect of poisoning is not obvious, and it will take effect after 12 hours after use

Method used

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  • Probiotic preparation capable of relieving acute alcoholism, and preparation method and application thereof
  • Probiotic preparation capable of relieving acute alcoholism, and preparation method and application thereof
  • Probiotic preparation capable of relieving acute alcoholism, and preparation method and application thereof

Examples

Experimental program
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Effect test

Embodiment 1

[0042] This embodiment provides a kind of probiotic preparation for alleviating acute alcoholism, and the raw material components include:

[0043] Bacteria powder of Lactobacillus rhamnosus XM106 (the number of live bacteria is 1.5×10 10 CFU / g), 10 parts by weight;

[0044] Bacteria powder of Bugatti yeast XM211 (the number of live bacteria is 1.5×10 10 CFU / g), 10 parts by weight;

[0045] Pyrroloquinoline quinone, 2 parts by weight;

[0046] Xylooligosaccharide, 18 parts by weight;

[0047] Inulin, 5 parts by weight;

[0048] Resistant dextrin, 75 parts by weight.

[0049] Further, the probiotic preparation for alleviating acute alcoholism is prepared by the following method:

[0050] (1) Take Lactobacillus rhamnosus XM106, anaerobically ferment and cultivate it in the fermentation medium at 36°C for 9 hours, obtain the fermented liquid and centrifuge it in a centrifuge, discard the supernatant, and collect the sludge of Lactobacillus rhamnosus XM106 The formula of th...

Embodiment 2

[0057] This embodiment provides a kind of probiotic preparation for alleviating acute alcoholism, and the raw material components include:

[0058] Bacteria powder of Lactobacillus rhamnosus XM106 (the number of live bacteria is 1.5×10 10 CFU / g), 5 parts by weight;

[0059] Bacteria powder of Bugatti yeast XM211 (the number of live bacteria is 1.5×10 10 CFU / g), 15 parts by weight;

[0060] Pyrroloquinoline quinone, 2 parts by weight;

[0061] Xylooligosaccharide, 18 parts by weight;

[0062] Inulin, 5 parts by weight;

[0063] Resistant dextrin, 75 parts by weight.

[0064] Further, the probiotic preparation for alleviating acute alcoholism is prepared by the following method:

[0065] (1) Take Lactobacillus rhamnosus XM106, anaerobically ferment and cultivate it in the fermentation medium at 36°C for 9 hours, obtain the fermented liquid and centrifuge it in a centrifuge, discard the supernatant, and collect the sludge of Lactobacillus rhamnosus XM106 The formula of the...

Embodiment 3

[0072] This embodiment provides a kind of probiotic preparation for alleviating acute alcoholism, and the raw material components include:

[0073] Bacteria powder of Lactobacillus rhamnosus XM106 (the number of live bacteria is 1.5×10 10 CFU / g), 15 parts by weight;

[0074] Bacteria powder of Bugatti yeast XM211 (the number of live bacteria is 1.5×10 10 CFU / g), 5 parts by weight;

[0075] Pyrroloquinoline quinone, 2 parts by weight;

[0076] Xylooligosaccharide, 18 parts by weight;

[0077] Inulin, 5 parts by weight;

[0078] Resistant dextrin, 75 parts by weight.

[0079] Further, the probiotic preparation for alleviating acute alcoholism is prepared by the following method:

[0080] (1) Take Lactobacillus rhamnosus XM106, anaerobically ferment and cultivate it in the fermentation medium at 36°C for 9 hours, obtain the fermented liquid and centrifuge it in a centrifuge, discard the supernatant, and collect the sludge of Lactobacillus rhamnosus XM106 The formula of the...

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Abstract

The invention relates to a probiotic preparation capable of relieving acute alcoholism, and a preparation method and an application thereof. The probiotic preparation is prepared by using lactobacillus rhamnosus and saccharomyces boulardii as raw materials through proper proportioning, wherein the lactobacillus rhamnosus has the effect of producing acetaldehyde dehydrogenase; the saccharomyces boulardii has the effects of producing ethanol dehydrogenase and acetaldehyde dehydrogenase; vitamin coenzyme with a redox coenzyme effect is also added; and thus, under the synergistic effect of all theraw material components, and through the influence on a plurality of ways like ethanol metabolism and lipid peroxidation to generate a liver cell protection effect, the finally-prepared probiotic preparation capable of relieving the acute alcoholism can significantly prolong the drunkenness tolerance time, can shorten the sleep time, can reduce the mass concentrations of ethanol and acetaldehyde,and has significant hangover alleviating effect on the acute alcoholism. The probiotic preparation provided by the invention can be directly taken after drinking, can relieve liver poisoning caused by ammonia after drinking or liver poisoning caused by acetaldehyde after drinking, and can be used for preparing medicines for treating alcoholic liver injury.

Description

technical field [0001] The invention belongs to the technical field of probiotics, and in particular relates to a probiotic preparation for alleviating acute alcoholism, a preparation method and an application. Background technique [0002] The World Health Organization reports that approximately 3 million people die each year from alcohol-related causes. Chronic alcoholism can lead to a range of physical ailments. Acute or chronic alcohol intake can lead to the formation of liver diseases (alcoholic hepatitis, steatosis, steatohepatitis, etc.). Drinking alcohol can increase lipogenesis and inhibit fatty acid oxidation. Alcoholic liver steatosis exceeds 90%. Most common, it is primarily characterized by excessive accumulation of lipid droplets in hepatocytes. [0003] After ingesting alcohol, part of the ethanol is first metabolized under the action of gastric mucosal alcohol dehydrogenase, and most of the ethanol is mainly metabolized in the liver, which is the main site ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/064A61K35/747A61P39/02A61P1/16
CPCA61K35/747A61K36/064A61P1/16A61P39/02A61K2300/00
Inventor 余卫雄
Owner 合肥微崇生物科技有限公司
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