Unlock instant, AI-driven research and patent intelligence for your innovation.

Freckle-removing composition for treating skin pigmentation and preparation method of freckle-removing composition

A technology of skin pigmentation and composition, applied in the field of skin care products, can solve problems such as weak skin tone

Inactive Publication Date: 2020-07-07
西安臻瑞生物科技有限公司
View PDF2 Cites 1 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, the combined use of chemical peeling and topical drugs has a certain effect on the treatment of PIH. The combination of tretinoin and hydroquinone is effective, but excessive stimulation may lead to more PIH.
Tyrosinase inhibitors or skin lighteners used in the treatment of melasma, such as hydroquinone, hydroquinone, azelaic acid, and kojic acid, have a significant disadvantage in treating melasma by making the background of the adjacent PIH site The skin tone becomes weaker and the pigmentation spots are highlighted, and the inflammatory pigmentation exists in the deeper layers of the skin (such as the papillary dermis), and it takes more than 6 months for the treatment to see the effect

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Freckle-removing composition for treating skin pigmentation and preparation method of freckle-removing composition
  • Freckle-removing composition for treating skin pigmentation and preparation method of freckle-removing composition

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0040] Formula: 0.2 parts of bisabolol, 2 parts of chamomile oil, 0.1 parts of lipoxin A4, 0.2 parts of ligustrazine, 1 part of glycyrrhizic acid, 0.5 parts of a-linolenic acid, 0.2 parts of tocopheryl acetate, caprylic acid / capric acid 3 parts triglyceride, 0.2 part ceramide, 0.5 part panthenol, 0.05 part sodium hyaluronate, 0.2 part sodium lactate, 3 parts hydrogenated polyisobutylene, 3 parts cyclopentasiloxane, isostearate 0.5 parts of acid, 2 parts of phytosterols, 1 part of steareth-2, 1 part of steareth-21, 2 parts of cetearyl alcohol, 5 parts of propylene glycol, 5 parts of butylene glycol, ethyl 0.27 parts of hexylglycerin, 0.03 parts of phenoxyethanol, 0.1 parts of methylparaben, and 68.95 parts of water.

[0041] The preparation method is as follows:

[0042] (1) Weigh the raw materials according to the above weight parts, and group them for later use; (2) Put the water phase material into the water phase pot of the homogeneous emulsification pot, stir and dissolve...

Embodiment 2

[0044] The formula of this embodiment 2 is the same as that of embodiment 1, but the temperature and time are different in the preparation method.

[0045] The preparation method is as follows:

[0046] (1) Weigh each raw material according to the above-mentioned parts by weight, and group them for later use; (2) Put the water phase material into the water phase pot of the homogeneous emulsification pot, stir and dissolve at a speed of 20 r / min, and heat to 83°C; The water phase material includes water, propylene glycol, butylene glycol, sodium hyaluronate, sodium lactate, methylparaben; (3) the oil phase material is put into the oil phase pot of the homogeneous emulsification pot, and the Stir at a rotating speed to dissolve, and heat to 83°C; the oil phase material includes steareth-2, steareth-21, cetearyl alcohol, caprylic / capric triglyceride, hydrogenated polyisobutene, Cyclopentasiloxane, isostearic acid, phytosterols, chamomile oil, tocopheryl acetate; (4) the water ph...

Embodiment 3

[0048] Formula: 0.5 parts of bisabolol, 2 parts of chamomile oil, 0.5 parts of lipoxin A4, 0.5 parts of ligustrazine, 1 part of glycyrrhizic acid, 0.5 parts of a-linolenic acid, 0.2 parts of tocopheryl acetate, caprylic acid / capric acid Triglyceride 3 parts, Ceramide 1 0.2 part, Panthenol 0.2 part, Sodium hyaluronate 0.05 part, Sodium lactate 0.2 part, Hydrogenated polyisobutylene 3 parts, Cyclopentasiloxane 3 parts, Isostearyl 0.5 parts of acid, 2 parts of phytosterols, 1.5 parts of steareth-2, 1.5 parts of steareth-21, 2 parts of cetearyl alcohol, 5 parts of propylene glycol, 5 parts of butylene glycol, ethyl 0.27 parts of hexylglycerin, 0.03 parts of phenoxyethanol, 0.1 parts of methylparaben, and 67.25 parts of water.

[0049] The preparation method is as follows:

[0050] (1) Weigh the raw materials according to the above weight parts, and group them for later use; (2) Put the water phase material into the water phase pot of the homogeneous emulsification pot, stir and d...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention discloses a freckle-removing composition for treating skin pigmentation and a preparation method of the freckle-removing composition. The composition consists of an anti-inflammatory agent, a skin conditioner, an emollient, an emulsifier, a moisturizer, a preservative and water in parts by weight, wherein the anti-inflammatory agent comprises bisabolol, chamomile oil, lipoxin A4, ligustrazine, glycyrrhizic acid and alpha-linolenic acid; the skin conditioner comprises tocopheryl acetate, caprylic / capric triglyceride, ceramide 1, panthenol, sodium hyaluronate and sodium lactate; the emollient comprises hydrogenated polyisobutene, cyclopentasiloxane, 0.2-1 part of isostearic acid and phytosterol; the emulsifier comprises steareth-2, steareth-21 and cetostearyl alcohol serving asa co-emulsifier; the moisturizer comprises propylene glycol and butanediol; and the preservative comprises ethylhexylglycerin, phenoxyethanol and methylparaben. The freckle-removing composition is simple in formula and convenient to use, and can be used for quickly treating chloasma.

Description

technical field [0001] The invention relates to the technical field of skin care products, in particular to a freckle-removing composition for treating skin pigmentation and a preparation method thereof. Background technique [0002] In the current situation where the natural environment is becoming increasingly harsh and the pressure of life is increasing rapidly, with age and improper skin care, melasma has become a relatively common skin pigmentation, so skin care products with whitening and anti-freckle effects are becoming more and more popular. people value. [0003] Although some factors are known to be involved in the development of melasma and to exacerbate symptoms, the underlying cause remains unclear. The essence of melasma is a chronic hyper-irritative inflammatory pigmentation. Post-inflammatory hyperpigmentation of the skin (PIH) is a disease of increased pigment synthesis and deposition caused by skin inflammation, which destroys the pigment amount regulati...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/34A61K8/36A61K8/365A61K8/37A61K8/42A61K8/49A61K8/63A61K8/67A61K8/73A61K8/92A61Q19/00A61Q19/02A61Q19/08
CPCA61K8/34A61K8/922A61K8/365A61K8/494A61K8/63A61K8/361A61K8/345A61K8/678A61K8/375A61K8/42A61K8/673A61K8/735A61Q19/02A61Q19/08A61Q19/00
Inventor 陈奶寿罗海浪徐佳洁陈明玉
Owner 西安臻瑞生物科技有限公司