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Composition and spray having sleep promoting efficacy, and preparation method of spray

A composition and efficacy technology, applied in the directions of drug combinations, skin care preparations, pharmaceutical formulations, etc., can solve the problems such as the inability to guarantee the effective performance of essential oil products, the huge difference in the proportion of effective fragrance components, and the uneven quality of raw materials, and achieve breakthrough Sleep disturbance, significant sleep aid effect, fast fragrance release effect

Inactive Publication Date: 2020-09-04
泉后(广州)生物科技研究院有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, according to market research, many consumers report that when using lavender essential oil, not only does it not have the effect of calming the nerves and helping sleep, but it has the effect of refreshing the mind and brain.
Moreover, the quality of raw materials in the essential oil market is uneven, and the origin of raw materials is not clear, resulting in a huge difference in the proportion of effective aroma components in essential oils, so that the effective use of the final efficacy of essential oil products cannot be guaranteed.
In addition, when preparing a spray with a sedative and hypnotic effect, many insoluble substances will be produced after mixing the fragrance ingredients, ethanol and water, and various chemical reactions such as transesterification, ester formation, and acetal reaction will easily occur. Blocks the perception of other odors in the spray, reducing the sleep aid effect

Method used

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  • Composition and spray having sleep promoting efficacy, and preparation method of spray
  • Composition and spray having sleep promoting efficacy, and preparation method of spray
  • Composition and spray having sleep promoting efficacy, and preparation method of spray

Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0058] The preparation method of the sleep-promoting spray that described natural fragrance is matched, comprises the steps:

[0059] (1) Mix the solvent and the cannabis leaf extract evenly, and set aside;

[0060] (2) Mix sandalwood oil, frankincense oil, neroli oil, and rosewood oil evenly, and set aside;

[0061] (3) Pour the mixture prepared in step (2) into the mixture prepared in step (1), stir evenly, add filter aid, stir evenly, let stand for 15 minutes, and then filter.

Embodiment 1-5

[0062] Embodiment 1-5 The sleep-promoting spray that natural fragrance is combined and preparation thereof

[0063] Table 5 shows the mass percent formula of the sleep-promoting spray blended with natural flavors in Examples 1-5.

[0064] table 5

[0065] Element Example 1 Example 2 Example 3 Example 4 Example 5 Cannabis Leaf Extract 2.0 3.0 2.0 2.0 4.0 sandalwood oil 4.0 3.0 2.0 1.0 0.4 frankincense oil 2.0 1.5 1.0 0.5 0.2 Neroli Oil 2.0 1.5 1.0 0.5 0.2 rosewood oil 2.0 1.5 1.0 0.5 0.2 QUIDEX 1 1.5 1 1 2.0 Extra Grade Odorless Ethanol 58 40 48 38 30 Deionized water To 100 To 100 To 100 To 100 To 100

[0066] The preparation method of the sleep-promoting spray that the natural fragrance of embodiment 1~4 is combined comprises the following steps:

[0067] (1) Mix the solvent and the cannabis leaf extract evenly, and set aside;

[0068] (2) Mix sandalwood oil, frankinc...

Embodiment 6

[0078] Embodiment 6 Sensory evaluation of sleep aid spray

[0079] Randomly select 50 subjects (18 males and 32 females) who have different degrees of sleep quality problems to score the sleep-promoting spray smell preference and degree of soothing and relaxing in Examples 1-6 and Comparative Examples 1-9 (experimental The evaluation will be completed within 72 hours after the room model is completed), and the scoring range is 1 to 10 points. The higher the score, the more popular the product smell and the more soothing and relaxing effect it has. The average value of each group is taken, and the calculation results are shown in Table 8.

[0080] Table 8

[0081] group odor degree of relief Example 1 9.5 9.7 Example 2 9.1 8.9 Example 3 8.8 8.4 Example 4 8.7 8.5 Example 5 8.3 8.1 Comparative example 1 7.6 7.5 Comparative example 2 7.2 5.9 Comparative example 3 5.8 5.2 Comparative example 4 6.7 6.3 ...

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Abstract

The invention discloses a composition and spray having sleep promoting efficacy, and a preparation method of the spray. The composition having sleep promoting efficacy comprises the following components of lignum santali albi oil, frankincense oil, bitter orange flower oil and rose wood in a mass ratio being (2-4) to (1-2) to (1-2) to (1-2). Besides, the invention also provides sleep promoting spray containing the composition. According to the composition and the spray disclosed by the invention, the collocation and the addition proportion of spice ingredients are strictly chosen, the spice ingredients and cannabis leaf extracts mutually cooperate and synergistically exert the sleep promoting efficacy, the smell is soothing and relaxing, and the sleep promoting effects are notable. Variousactive substances in the spray are selected from natural plants and do not contain hazardous substances, so that the spray does not have side effects, is natural and safe, and can be used for a longtime. Besides, when the sleep promoting spray is used, fragrance is quick to release and mild, and fragrance release is more comprehensive. Products are simple in making technology, controllable in the proportion of fragrance components, low in cost and suitable for industrial production.

Description

technical field [0001] The invention belongs to the technical field of cosmetics. More specifically, it relates to a composition, a spray and a preparation method thereof with a sleep-promoting effect. Background technique [0002] Sleep disturbance is the main manifestation of insomnia, which can be early stage insomnia (difficulty falling asleep), middle stage insomnia (light sleep, easy to wake up), terminal stage insomnia (early awakening), dreaminess, nightmares, no sleep feeling, sleepiness, etc. After not recovering from fatigue, etc., appealing symptoms can also be mixed. Today, sleep disorders have become a modern urban disease and a social problem that cannot be ignored. The "2019 China Sleep Index Report" shows that 21.5% of Chinese people often suffer from insomnia. Among the post-90s population, 31% have the habit of going to bed late, more than 60% feel that they do not get enough sleep, and only 5% think they can enjoy good sleep. In addition, according to...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/9789A61K8/92A61K8/04A61P25/20A61Q19/00
CPCA61K8/922A61K8/9789A61K8/046A61Q19/00A61P25/20
Inventor 钟玉容张娇韩志东
Owner 泉后(广州)生物科技研究院有限公司
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