Nasal spray for preventing flu based on red pepper extract and heparin and preparation method thereof

A red pepper extract, nasal spray technology, applied in aerosol delivery, medical preparations with inactive ingredients, medical preparations containing active ingredients, etc. Pressure, increase the frequency of use and other problems, to achieve the effect of short maintenance time, reduce side effects, and reduce the frequency of use

Inactive Publication Date: 2021-03-12
QUFU NORMAL UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] The current nasal sprays are all for the purpose of sterilization and disinfection, mostly physiological saline, and added bactericides such as aspirin, ibuprofen, chlorpheniramine and other antibiotics. Most germs can sterilize the nasal cavity to a certain extent, but it is ignored that the use of drugs and antibiotics to clean or sterilize the nasal cavity will increase the side effects on the human body and the degree of harm to the drug, and most products on the market have a single effect, and when used The effect of nasal flushing lasts for a short time. Some patients with dry, itchy and astringent noses often return to the dry and itchy state shortly after spraying the nasal cavity. Individual patients have to increase the frequency of use due to work or other needs. Life brings inconvenience, and increases the pressure on the nasal cavity, so that when the nasal cavity patients cannot achieve the expected effect of using the product, they increase the frequency of use, causing a lot of unnecessary troubles

Method used

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  • Nasal spray for preventing flu based on red pepper extract and heparin and preparation method thereof
  • Nasal spray for preventing flu based on red pepper extract and heparin and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0024] A nasal spray, by weight percentage, comprising the following components: γ-PGA-CS: 10%, glycerin: 5%, capsicum extract: 2%, heparin solution: 5%, ethanol: 2%, Balance: purified water.

[0025] A preparation method of nasal cavity spray, the method comprises the following steps:

[0026] Step 1: dissolving chitosan in 95% acetic acid solution, stirring evenly at room temperature, diluting it with deionized water to obtain 70% chitosan solution; adding poly70% gamma-glutamic acid solution dropwise to In an equal volume of 70% chitosan solution, stir magnetically, mix thoroughly, and freeze-dry to obtain poly-γ-glutamic acid / chitosan dry powder, which can be dissolved in water to obtain 10g / LA liquid;

[0027] Step 2: After drying 50 g of pepper at 40°C, pulverize it with a pulverizer, repeatedly extract it with ethanol, obtain the pepper extract after vacuum drying, and dissolve it with 30% ethanol water to obtain a 3g / LB solution;

[0028] Step 3: Dissolving heparin i...

Embodiment 2

[0033] A nasal spray, by weight percentage, comprising the following components: γ-PGA-CS: 10%, glycerin: 7%, capsicum extract: 2%, heparin solution: 8%, ethanol: 2%, Balance: purified water.

[0034] The preparation method is the same as in Example 1.

Embodiment 3

[0036] A nasal spray, by weight percentage, comprising the following components: γ-PGA-CS: 10%, glycerin: 10%, capsicum extract: 2%, heparin: 10%, ethanol: 2%, Quantity: Purified water.

[0037] The preparation method is the same as in Example 1.

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PUM

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Abstract

The invention belongs to the technical field of medicine preparation, and particularly relates to a nasal spray for preventing flu based on a red pepper extract and heparin and a preparation method thereof. The nasal spray is prepared from the following raw materials in parts by weight: 10% of gamma-PGA-CS, 5-10% of glycerol, 2% of a red pepper extract, 5-10% of a heparin solution, 2-2.4% of ethanol and the balance of purified water. The nasal spray can inhibit bacteria and diminish inflammation, has a good treatment effect on rhinitis, can keep the inner surface of the nasal cavity moist fora long time, and reduces side effects on a human body by changing the types of bactericides in the nasal spray, so that the nasal cavity is kept clean and moist for a long time.

Description

technical field [0001] The invention belongs to the technical field of medicine preparation, and in particular relates to a nasal spray for preventing influenza based on red pepper extract and heparin and a preparation method thereof. Background technique [0002] Everyone knows the importance of breathing to sustain life, and the nasal cavity is the first guard of the respiratory system. According to calculations, a normal adult inhales and exhales 15,000 liters of air 24 hours a day. People are selective about the drinking water they need every day, but they have no choice about the air they need to breathe every moment. Everyone inhales air of different quality because of their different environments. With the development of industrial production and transportation, there are more and more harmful substances such as dust, smoke, organic poisons and bacteria in the air, and more and more harmful substances are retained in the vestibule of the nasal cavity. The dirt cannot...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/12A61K47/36A61K47/34A61K47/10A61K36/81A61K31/727A61P11/02A61P31/04A61P31/16
CPCA61K9/0043A61K47/36A61K47/34A61K47/10A61K36/81A61K31/727A61P11/02A61P31/04A61P31/16A61K9/12A61K2300/00A61K2236/15A61K2236/333A61K2236/51
Inventor 杨革刘逸霏车程川刘金锋巩志金孙阳陈琦
Owner QUFU NORMAL UNIV
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