Nasal spray for preventing flu based on red pepper extract and heparin and preparation method thereof
A red pepper extract, nasal spray technology, applied in aerosol delivery, medical preparations with inactive ingredients, medical preparations containing active ingredients, etc. Pressure, increase the frequency of use and other problems, to achieve the effect of short maintenance time, reduce side effects, and reduce the frequency of use
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Embodiment 1
[0024] A nasal spray, by weight percentage, comprising the following components: γ-PGA-CS: 10%, glycerin: 5%, capsicum extract: 2%, heparin solution: 5%, ethanol: 2%, Balance: purified water.
[0025] A preparation method of nasal cavity spray, the method comprises the following steps:
[0026] Step 1: dissolving chitosan in 95% acetic acid solution, stirring evenly at room temperature, diluting it with deionized water to obtain 70% chitosan solution; adding poly70% gamma-glutamic acid solution dropwise to In an equal volume of 70% chitosan solution, stir magnetically, mix thoroughly, and freeze-dry to obtain poly-γ-glutamic acid / chitosan dry powder, which can be dissolved in water to obtain 10g / LA liquid;
[0027] Step 2: After drying 50 g of pepper at 40°C, pulverize it with a pulverizer, repeatedly extract it with ethanol, obtain the pepper extract after vacuum drying, and dissolve it with 30% ethanol water to obtain a 3g / LB solution;
[0028] Step 3: Dissolving heparin i...
Embodiment 2
[0033] A nasal spray, by weight percentage, comprising the following components: γ-PGA-CS: 10%, glycerin: 7%, capsicum extract: 2%, heparin solution: 8%, ethanol: 2%, Balance: purified water.
[0034] The preparation method is the same as in Example 1.
Embodiment 3
[0036] A nasal spray, by weight percentage, comprising the following components: γ-PGA-CS: 10%, glycerin: 10%, capsicum extract: 2%, heparin: 10%, ethanol: 2%, Quantity: Purified water.
[0037] The preparation method is the same as in Example 1.
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