Composition for treating acne, preparation method therefor and application of composition

A composition and technology for acne, applied in the field of skin care products, can solve problems such as satisfactory results for people with difficult acne, uncertain clinical effects, unclear toxic and side effects, etc., achieve pigmentation, moisturizing and skin barrier repair, and reduce pigmentation. The effect of repairing skin barrier, prescription and simple production process

Inactive Publication Date: 2021-04-02
广州膜束生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The main mechanism of action of this type of drug is to inhibit sebum secretion and improve pilosebaceous duct keratinization. Although it has good clinical effects, it has the following disadvantages: (1) Strong skin irritation and keratin exfoliation, a large number of people with sensitive skin cannot Tolerant and cannot be used; (2) damage the skin barrier, which is not conducive to the fundamental restoration of healthy skin quality, so it cannot be used for a long time to prevent acne; (3) has certain toxic and side effects such as teratogenicity and photosensitivity, and is prohibited by national laws (4) The effect is not comprehensive enough
2. Benzoyl peroxide gel is a peroxide, which can slowly release new ecological oxygen and benzoic acid after external use, and has the effect of inhibiting Propionibacterium acnes and anti-acne. The main disadvantages are: (1) It has strong Skin irritation, people with sensitive skin can’t tolerate it and can’t use it; (2) It has certain toxic and side effects such as carcinogenicity, so it is not suitable for long-term use, and the national law prohibits it from being used in skin care products; (3) The effect is not comprehensive enough
The main mechanism of action of this kind of substance is to inhibit pathogenic microorganisms such as Propionibacterium acnes, and it has good clinical effect on acne mainly caused by inflammatory papules, but the main disadvantages are as follows: (1) Long-term use can cause antibiotic resistance; (2) National laws prohib

Method used

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  • Composition for treating acne, preparation method therefor and application of composition
  • Composition for treating acne, preparation method therefor and application of composition
  • Composition for treating acne, preparation method therefor and application of composition

Examples

Experimental program
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Effect test

Embodiment 1

[0048]A composition for treating acne, including the following ingredients: cyclodextrin wrapped 2kg, cyclodextrial package wrapped 2kg, glycyridic acid inositol choline salt 10g, carnamerin 300g, petroleum 50g, hexamidine Different (hydroxyethylsulfonic acid) salt 95g, bisquadol 4kg, cetyl alkyl alcohol 2 kg, ispanic acid ishylacetin 3kg, polydimethylsiloxane 4 kg, PEG-100 stearate 1kg , Glycerol stearate 500g, C14-22 alcohol 1 kg, C12-20 alkyl glucoside 1 kg, polyacrylamide 150g, C13-14 ischarin 50g, lauryl polyether-7 50g, arginine 1kg, pair Hydroxyacetophenone 2kg, add water to 100 kg.

[0049]The treatment of acne has a preparation method comprising the steps of:

[0050](1) We need the required raw materials in accordance with the formulation;

[0051](2) Place a water of 80% of the formulation in aqueous phase, heated to about 70 ° C, adding double propanol, stirring to a uniform transparent and disconnected;

[0052](3) Castle sodaryol, abhylactyl ishyricate, polydimethylsiloxane, PEG-1...

Embodiment 2

[0058]A composition for treating acne, including the following ingredients: cyclodextrin wrapped in 500g, cyclodextrin wrapped in 3kg, glycyridic acid inositol choline salt 50g, pestoin 50g, pendallmol 100g, hexamidine Ding (hydroxyethylsulfonic acid) salt 50g, 1,2-hexanediol 3kg, propylene glycol 3kg, olive oil 2kg, avocado oil 3 kg, PEG-100 stearate 1.2kg, glycerin stearate 700g, C14 -22 alcohol 1kg, C12-20 alkyl glucoside, Polyacrylamide 100g, C13-14 isoaraffin 70g, lauryl polyether-7 100g, arginine 700g, 2 kg of hydroxybenzene, water to 100 kg .

[0059]The treatment of acne has a preparation method comprising the steps of:

[0060](1) We need the required raw materials in accordance with the formulation;

[0061](2) Place a water of 80% of the formulation in aqueous phase, heated to about 70 ° C, adding double propanol, stirring to a uniform transparent and disconnected;

[0062](3) Castle sodaryol, abhylactyl ishyricate, polydimethylsiloxane, PEG-100 stearate, glycerol stearate, C14-22 al...

Embodiment 3

[0068]A composition for treating acne, including the following ingredients: cyclodextrin wrapheralated 4kg, cyclodextrin package wrapped in 2kg, glycyridic acid inositol choline salt 100g, carnamer 500g, pendallmins 10g, hexamidine Different (hydroxyethylsulfonic acid) salt 400g, bisylglycol 2 kg, propylene glycol 3kg, whale wax stearate 4 kg, polydimethylsiloxane 4 kg, PEG-100 stearate 1.5kg, glycerol Acid esters 1kg, polyacrylamide 150g, C13-14 isoalkane 100g, lauryl polyether -7100 g, arginine 500g, 2 kg of hydroxyacetophenone, water to 100 kg.

[0069]The treatment of acne has a preparation method comprising the steps of:

[0070](1) We need the required raw materials in accordance with the formulation;

[0071](2) Place a water of 80% of the formulation in aqueous phase, heated to about 70 ° C, adding double propanol, stirring to a uniform transparent and disconnected;

[0072](3) Castle sodaryol, abhylactyl ishyricate, polydimethylsiloxane, PEG-100 stearate, glycerol stearate, C14-22 alco...

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PUM

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Abstract

The invention relates to a composition for treating acne, a preparation method therefor and application of the composition. The composition for treating the acne, prepared by the preparation method, has the effects of inhibiting secretion of sebum, improving keratinization of follicle sebaceous gland catheters, inhibiting pathogenic microorganisms such as propionibacterium acnes, alleviating inflammatory reactions, alleviating pigmentation, preserving moisture and repairing skin barrier and is comprehensive in action and relatively good in treatment effect. The composition for treating the acne, disclosed by the invention, can be used for preserving moisture, alleviating pigmentation and repairing skin barrier while removing acne, so that fat is controlled, and skin is comfortable and notdry. The composition for treating the acne, disclosed by the invention, is simple in prescription and production process, raw materials employed all are in line with national specifications for cosmetic raw materials, the use safety is good, and the composition has a broad market prospect.

Description

Technical field[0001]The present invention belongs to the field of skin care products, and more particularly to compositions for treating acne and preparation methods and applications thereof.Background technique[0002]Acne, commonly known as acne, is a chronic inflammatory skin disease of hair follicle sebaceous glands, which is used in the youth population. It is often seen in the face. Clinical manifestations have acne, inflammatory puple, pustule, nodules and cysts. The most important mechanism of acne is: the secretion of sebum is prosperous, and the hair follicle sebaceous adenocarcothe is overgrained and clogged, and acne is the main microorganism infection, inflammatory response, etc., and often occurs in pigmentation and skin barrier damage. Therefore, the mechanism of controlling acne products should also focus from the following aspects: (1) inhibit sebaceous secretion; (2) Improve hair follicular sebaceous adenocarcode; (3) inhibit pathogenic microorganisms such as acne p...

Claims

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Application Information

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IPC IPC(8): A61K8/92A61K8/73A61K8/362A61K8/55A61K8/368A61K8/49A61K8/46A61Q19/00A61Q19/02A61P17/10
CPCA61K8/922A61K8/738A61K8/362A61K8/55A61K8/368A61K8/4946A61K8/466A61Q19/00A61Q19/02A61Q19/008A61P17/10
Inventor 范剑环王华君吕文杰苏红雷许容
Owner 广州膜束生物科技有限公司
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