Synthesis method of water-soluble fluorescent probe and application of the water-soluble fluorescent probe to detection of antibiotics

A fluorescent probe and synthesis method technology, applied in the field of detection of antibiotics, water-soluble fluorescent probes and their synthesis, can solve the problems of complex detection steps, long detection time, poor practicability, etc., and achieve short detection time, high sensitivity, and responsiveness The effect of mild conditions
CN112724166AActive Publication Date: 2021-04-30JIANGSU UNIV
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
JIANGSU UNIV
Publication Date
2021-04-30

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Abstract

The invention belongs to the technical field of chemical analysis and detection, and particularly relates to a synthesis method of a water-soluble fluorescent probe and application of the water-soluble fluorescent probe to detection of antibiotics. The fluorescent probe is prepared from raw materials such as 2,4-dimethylpyrrole, methyl p-formylbenzoate, trifluoroacetic acid, DDQ, triethylamine and a boron trifluoride diethyl etherate complex under mild reaction conditions, and is used for detecting the content of antibiotics in food, environment and other samples, such as roxithromycin, tetracycline and oxytetracycline. The detection method has the advantages of high sensitivity, good selectivity, short detection time and the like.
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Description

technical field

[0001] The invention belongs to the technical field of chemical analysis and detection, and specifically introduces a water-soluble fluorescent probe, a synthesis method thereof and an application for detecting antibiotics. Background technique

[0002] Antibiotics are physiologically active substances whose main function is to fight against bacterial infection. They can kill and inhibit pathogenic bacteria that invade the organism, effectively control the infection, and eventually make the body heal. There are many types of antibiotics, including tetracyclines, macrolides, β-lactams, etc. Both Oxytetracycline (OTC) and Tetracycline (TET) belong to tetracycline antibiotics, and are mainly used as veterinary drugs for the treatment of animal infectious diseases. Roxithromycin is a kind of macrolide antibiotics, which is widely used in human bacterial infection diseases, and has a good curative effect on respiratory tract infections, pharyngitis and pneumonia ...

Claims

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