Chitosan-alginate composite nanofiber membrane as well as preparation method and application thereof

Abstract

The invention provides a chitosan-alginate composite nanofiber membrane as well as a preparation method and application thereof. The method comprises the following steps of dissolving alginate in a first solvent to obtain a first mixed solution with the mass concentration of 6-12%; dissolving chitosan and gelatin in a second solvent to obtain a second mixed solution with the mass concentration of 1-8%; and mixing the first mixed solution with the second mixed solution to obtain a spinning solution, introducing the spinning solution into an injector for electrostatic spinning, and performing drying to obtain the chitosan-alginate composite nanofiber membrane. The preparation method of the chitosan-alginate composite nanofiber membrane is simple to operate, low in time consumption and high in efficiency. The nanofiber membrane prepared by the method has good mechanical property, water resistance and biocompatibility.

Description

technical field [0001] The invention relates to a chitosan-alginate composite nanofiber membrane and a preparation method and application thereof. Background technique [0002] Electrospinning is an important method for preparing ultrafine fibers. It is mainly to bring thousands to tens of thousands of volts of high-voltage static electricity to the polymer solution or melt, and the charged polymer droplets are stretched under the action of the electric field force. . When the electric field force is strong enough, the polymer droplets can overcome the surface tension to form a jet stream. The thin stream evaporates the solvent during the injection process, the fibers solidify, and finally fall on the receiving device to form a fiber mat similar to a non-woven fabric. Fibers prepared by electrospinning are much thinner than traditional methods, and their diameters are generally between tens of nanometers and hundreds of nanometers. [0003] Chitosan is used as an importan...

AI Technical Summary

Problems solved by technology

[0003] Chitosan is used as an important heavy metal-based adsorbent because it contains functional groups such as amino groups and hydroxyl groups. However, due to its high viscosity in acidic solutions, positive charges, and strong intramolecular and intermolecular chemical bonds , making it difficult to move freely during electrospinning, resulting in discontinuous fibers, beads, and even spinning breakage

For this reason, people once blended polymers such as oxyethylene, polyvinyl alcohol, polyethylene terephthalate, cellulose, polycaprolactone and chitosan to enhance the toughness and strength of spinning, but There are still technical problems such as the interaction between polymers, impurity problems, and the complexity of the process due to the large number of parameters, which make it difficult to predict the results.