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Polycarbophil calcium tablet, and preparation method and application thereof

A technology of polycarbophil calcium and isomaltooligosaccharides, which is applied in the direction of pharmaceutical formulations, medical preparations containing active ingredients, and artificially synthesized active ingredients of polymeric materials, can solve the problem of inability to provide health care and antibacterial, and produce sticky Problems such as thick matter and single ingredients, to achieve the effect of being suitable for large-scale production, low production cost, and improving therapeutic effect

Inactive Publication Date: 2021-08-13
南京维垣生物技术有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the existing polycarbophil calcium tablets have a single component and have a single therapeutic effect, which cannot provide health care and antibacterial effects. In addition, polycarbophil calcium will absorb water in advance in the oral cavity. Carrier polycarbophil calcium tablets can create a sticky substance in the mouth and make swallowing difficult or require large amounts of water to complete the swallowing process

Method used

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  • Polycarbophil calcium tablet, and preparation method and application thereof
  • Polycarbophil calcium tablet, and preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0051] A kind of polycarbophil calcium tablet, this polycarbophil calcium tablet is made of the raw material of following mass parts:

[0052] Polycarbophil calcium 100g, Coptis 0.5g, Schisandra 0.5g, Scutellaria baicalensis 0.5g, Patchouli 0.5g, Pueraria 0.5g, Carboxymethyl starch 20g, Hawthorn 1g, Rhubarb 0.5g, Woody 0.5g, Citrus aurantium 0.5 g, oat fiber 10g, fructose 5g, andrographis 0.5g, purslane 0.5g, Pulsatilla 0.5g and honeysuckle 0.5g.

[0053] The preparation of this polycarbophil calcium tablet comprises the following steps:

[0054] Weigh polycarbophil calcium 100g and carboxymethyl starch 20g, adopt the method of increasing in equal amounts to mix, and mix uniformly to form a mixture for subsequent use;

[0055] Weigh 10g of oat fiber and 5g of fructose for pre-mixing. After mixing evenly, fully mix with mixture 1, chop up after making tablets, repeat 3 times, and pass through a 40-60 mesh sieve to form mixture 2;

[0056] Coptidis 0.5g, Schisandra 0.5g, Scute...

Embodiment 2

[0059] A kind of polycarbophil calcium tablet, this polycarbophil calcium tablet is made of the raw material of following mass parts:

[0060] Polycarbophil calcium 125g, Coptis 0.75g, Schisandra 0.75g, Scutellaria baicalensis 0.65g, Patchouli 0.65g, Pueraria 0.75g, Carboxymethyl starch 25g, Hawthorn 1.25g, Rhubarb 0.65g, Woody fragrance 0.75g, Citrus aurantium 0.75g, oat fiber 15g, fructose 7.5g, andrographis 0.75g, purslane 0.75g, pulsatilla 0.75g and honeysuckle 0.75g.

[0061] The preparation of this polycarbophil calcium tablet comprises the following steps:

[0062] Weigh polycarbophil calcium 125g and carboxymethyl starch 25g, adopt the method for increasing in equal amounts to mix, and mix uniformly to form a mixture for subsequent use;

[0063] Weigh 15g of oat fiber and 7.5g of fructose for pre-mixing. After mixing evenly, fully mix with mixture 1, chop up after making tablets, repeat 3 times, and pass through a 40-60 mesh sieve to form mixture 2;

[0064] Coptis 0...

Embodiment 3

[0067] A kind of polycarbophil calcium tablet, this polycarbophil calcium tablet is made of the raw material of following mass parts:

[0068] Polycarbophil calcium 150g, berberine 1g, schisandra 1g, baicalin 0.8g, patchouli 0.8g, kudzu root 1g, carboxymethyl starch 30g, hawthorn 1.5g, rhubarb 0.8g, woody 1g, aurantium 1g, oat fiber 20g, fructose 10g, andrographis 1g, purslane 11g, Pulsatilla 1g and honeysuckle 1g.

[0069] The preparation of this polycarbophil calcium tablet comprises the following steps:

[0070] Weigh polycarbophil calcium 150g and carboxymethyl starch 30g, adopt the method for increasing in equal amounts to mix, and mix uniformly to form a mixture for subsequent use;

[0071] Weigh 20g of oat fiber and 10g of fructose for pre-mixing. After mixing evenly, fully mix with mixture 1, chop up after making tablets, repeat 3 times, and pass through a 40-60 mesh sieve to form mixture 2;

[0072] Coptidis 1g, Schisandra 1g, Scutellaria baicalensis 0.8g, Patchouli...

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Abstract

The invention discloses a polycarbophil calcium tablet, and a preparation method and application thereof. The polycarbophil calcium tablet comprises the following raw material ingredients: 100-150g of polycarbophil calcium, 5-10g of treatment auxiliary materials, 20-30g of carboxymethyl starch, 5-10g of conditioning auxiliary materials, 10-20g of Avena sativa L. fibers, 5-10g of sugar and 5-10g of anti-bacteria auxiliary materials. The polycarbophil calcium tablet has the beneficial effects that the traditional Chinese medicine compound compositions of the polycarbophil calcium tablet are from a classic prescription and are combined with modern clinical practical experience to obtain the polycarbophil calcium tablet, meanwhile, auxiliary traditional Chinese medicines are added, an eating way is improved, a modern technology is adopted to extract raw material medicines so as to keep effective ingredients in the raw material medicines and remove ineffective ingredients in the raw material medicines, finally, a dosage proportion is optimized, even design is adopted to carry out optimal proportion screening, and finally, tablets of different dosage forms are prepared to adapt to crowds with different requirements. The medicine preparation method provided by the invention adopts a simple screening and separating technology, and therefore, the medicine preparation method has high maneuverability and a low production cost and is suitable for mass production.

Description

technical field [0001] The invention relates to the technical field of medicine preparation, in particular to a polycarbophil calcium tablet and a preparation method and application thereof. Background technique [0002] Irritable bowel syndrome is a disease that can cause abnormal defecation even in the absence of organic disorders, usually caused by functional abnormalities in the distal digestive tract, and can generally be divided into the following categories: spastic contraction of the terminal colon, etc. Constipation type caused by delayed delivery of contents; diarrhea type caused by increased peristalsis and other promotion of contents delivery; alternate type in which constipation and diarrhea are repeated sequentially. [0003] For the treatment of constipation, clinically, except for a small number of critically ill patients, surgery is used, and the others are all treated with drugs. In general, according to the different mechanisms of drugs, they can be divid...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/752A61K36/79A61K9/20A61K31/78A61P1/00A61P31/04
CPCA61K31/78A61K9/2059A61K36/718A61K36/79A61K36/57A61K36/539A61K36/532A61K36/488A61K36/734A61K36/708A61K36/285A61K36/752A61K36/19A61K36/185A61K36/71A61K36/355A61K9/2095A61P1/00A61P31/04A61K2300/00
Inventor 孙浩张瑾向齐琦
Owner 南京维垣生物技术有限公司
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