Method for modifying chitosan in nitrogen environment

Abstract

The invention discloses a method for modifying chitosan in a nitrogen environment, which comprises the steps of S1, slowly adding water into a dilute acetic acid solution, mixing to obtain a dilute acetic acid solution with the mass fraction of 10%, dissolving chitosan into the dilute acetic acid solution with the mass fraction of 10%, stirring and mixing for 20 minutes at the temperature of 30 DEG C to obtain acidified chitosan; and S2, slowly adding water into the diluted hydrochloric acid solution, mixing to obtain a diluted hydrochloric acid solution with the mass fraction of 4%, dissolving succinic anhydride into the diluted hydrochloric acid solution with the mass fraction of 4%, and mixing and stirring at normal temperature. The solution is mixed in a nitrogen environment, other gas components in the air are prevented from participating in the reaction, the reaction condition is mild, reagents used in the reaction are easy to obtain, the production cost is reduced, tension treatment is achieved by utilizing the swelling effect of dilute acetic acid on chitosan fibers, chitosan is modified through succinic anhydride and diluted hydrochloric acid, and the moisture absorption and moisture retention properties of the chitosan are effectively improved.

Description

technical field [0001] The invention relates to the technical field of chitosan, in particular to a modification method of chitosan in a nitrogen environment. Background technique [0002] Chitosan is the product of natural polysaccharide chitin by removing part of the acetyl group. It has various physiological functions such as biodegradability, biocompatibility, non-toxicity, antibacterial, anticancer, lipid-lowering, and immune enhancement. It is widely used in food Additives, textiles, agriculture, environmental protection, beauty care, cosmetics, antibacterial agents, medical fibers, medical dressings, artificial tissue materials, drug sustained-release materials, gene transduction carriers, biomedical fields, medical absorbable materials, tissue engineering carrier materials, Many fields such as medical treatment and drug development and other daily chemical industries. [0003] The amino groups in the chitosan molecular structure are more reactive than the acetamido ...

AI Technical Summary

Problems solved by technology

[0004] As tissue scaffolds and drug carriers, chitosan and its derivatives have the functions of promoting wound healing, preventing tissue adhesion, anticoagulation, lowering lipid, lowering cholesterol, antiulcer, and antitumor, etc., and are often used as medical sutures, but Affected by raw materials, the main reason restricting the development of chitosan fiber is that the mechanical strength of chitosan fiber is not high. The breaking strength of chitosan fiber obtained by conventional spinning is only 1.07cN / dtex, which is far from reaching the limit of practical application. Require