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Whitening and spot-fading compound preparation with fructus phyllanthi fresh fruit pulp as main raw material and preparation method of whitening and spot-fading compound preparation

A technology of olive fresh fruit and compound preparation, applied in the field of whitening and lightening skin care, can solve the problems of reducing the intrinsic quality and function of Yunnan olive products, destroying nutrients and active ingredients, and complex extraction process, achieving better effect and simple preparation process. , the effect of improving economic benefits and comprehensive utilization

Active Publication Date: 2021-11-02
KUNMING MEDICAL UNIVERSITY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The skin care products containing Yunnan olives on the market all use the method of adding Yunnan olive extracts, which further destroys its rich nutrients and active ingredients, and the ingredients are relatively simple, and the extraction process is also relatively complicated, which reduces the quality of Yunnan olive products to a certain extent. Intrinsic qualities and functions of

Method used

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  • Whitening and spot-fading compound preparation with fructus phyllanthi fresh fruit pulp as main raw material and preparation method of whitening and spot-fading compound preparation
  • Whitening and spot-fading compound preparation with fructus phyllanthi fresh fruit pulp as main raw material and preparation method of whitening and spot-fading compound preparation
  • Whitening and spot-fading compound preparation with fructus phyllanthi fresh fruit pulp as main raw material and preparation method of whitening and spot-fading compound preparation

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0045] A kind of skin care lotion with Yunnan olive fresh fruit pulp as main raw material and its preparation method, through the following steps:

[0046](1) Raw materials are prepared according to the following mass percentages: 10% green thorn fruit oil, 70.7% Yunnan olive fresh fruit pulp, 0.2% sodium hyaluronate, 4% glycerin, 1% cetyl alcohol, 1% stearyl alcohol, wool 0.5% butter, 0.5% stearic acid, 3% butylene glycol, 4% 1,2-pentanediol, 1.5% glyceryl monostearate, 1% polydimethylsiloxane, poloxamer 188 1.5%, xanthan gum 0.3%, triethanolamine 0.5%, phenoxyethanol 0.3%;

[0047] (2) Take green thorn fruit oil, cetyl alcohol, stearyl alcohol, stearic acid, lanolin, polydimethylsiloxane, glyceryl monostearate, poloxamer 188 and add them to the oil phase pot, Heat to 70°C, stir evenly to make it fully melted and mixed;

[0048] (3) Add glycerin, butylene glycol, xanthan gum, sodium hyaluronate, and Yunnan olive fresh fruit pulp into the water phase pot, heat to 70°C, stir ...

Embodiment 2

[0056] A kind of skin care lotion with Yunnan olive fresh fruit pulp as main raw material and its preparation method, through the following steps:

[0057] (1) Raw materials are prepared according to the following mass percentages: green thorn fruit oil 8%, Yunnan olive fresh fruit pulp pulp 70.7%, sodium hyaluronate 0.3%, glycerin 4%, cetyl alcohol 2%, stearyl alcohol 2%, wool 0.5% butter, 0.5% stearic acid, 3% butylene glycol, 4% 1,2-pentanediol, 1.5% glyceryl monostearate, 1% polydimethylsiloxane, poloxamer 188 1.5%, xanthan gum 0.2%, triethanolamine 0.5%, phenoxyethanol 0.3%;

[0058] (2) Take green thorn fruit oil, cetyl alcohol, stearyl alcohol, stearic acid, lanolin, polydimethylsiloxane, glyceryl monostearate, poloxamer 188 and add them to the oil phase pot, Heat to 70°C, stir evenly to make it fully melted and mixed;

[0059] (3) Add glycerin, butylene glycol, xanthan gum, sodium hyaluronate, and Yunnan olive fresh fruit pulp into the water phase pot, heat to 70°C, ...

Embodiment 3

[0067] Determination of vitamin C content in emulsion by HPLC method:

[0068] Preparation of reference solution:

[0069] Accurately weigh 0.0041g of vitamin C reference substance (Beijing Zhongke Quality Inspection Biological Co., Ltd.) (50-81-7) (purity ≥ 98%), add acetonitrile-water (2:1) mixed solution to make up to 100mL capacity in the bottle.

[0070] The concentration of the reference solution is: Preparation of sample solution:

[0071] Accurately weigh 2g of the emulsion, place it in a 250mL Erlenmeyer flask, accurately add 50mL of acetonitrile-water (2:1) mixed solution, weigh the weight, ultrasonicate for 30min, weigh again, and use acetonitrile-water (2:1) The mixed solution made up for weight loss, shaken up, filtered, and the filtrate was taken.

[0072] test methods:

[0073] Chromatographic conditions: octadecylsilane bonded silica gel as filler; acetonitrile-0.01mol / L potassium dihydrogen phosphate aqueous solution (80:20) as mobile phase; detection wa...

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Abstract

The invention provides a whitening and spot-fading compound preparation with fresh fructus phyllanthi pulp as a main raw material and a preparation method thereof. Main active ingredients of the whitening and spot-fading compound preparation comprise fresh fructus phyllanthi pulp and prinsepia utilis royle oil. The compound preparation provided by the invention takes fresh fructus phyllanthi fresh fruit pulp as a main raw material, and can effectively inhibit the activity of tyrosinase so as to inhibit the formation of melanin, so that the compound preparation can improve the dull skin, brighten the skin color, improve the skin quality and nourish the skin. The whitening and spot-fading compound preparation can be applied to pigmented diseases, such as chloasma, melanosis, hyperpigmentation after inflammation, seborrheic keratosis, spina formosa, freckles, sunburn and the like. The whitening and spot-fading compound preparation can also be applied to daily whitening and skin care, blackening of skin after solarization and the like. The whitening and spot-fading compound preparation provided by the invention is natural and healthy in components, mild and safe in texture, simple in preparation method, easy to operate and suitable for large-scale production.

Description

technical field [0001] The invention relates to the technical field of whitening and blemish-reducing skin care, in particular to a compound preparation with fresh olive fruit pulp from Yunnan as the main raw material and a preparation method thereof. Background technique [0002] With the rapid development of the cosmetics market and the improvement of people's material living standards, people's pursuit of beauty is becoming more and more intense, and cosmetics have become national daily consumer goods. In the cosmetics market, skin care products account for the largest proportion, especially whitening products. However, some whitening cosmetics have potential safety hazards such as high levels of hormones, lead, and mercury, and may even cause more serious damage to the skin. Whitening and lightening drugs such as hydroquinone and kojic acid are prohibited from being used in skin care products due to problems such as cytotoxicity, carcinogenicity, local irritation, and e...

Claims

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Application Information

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IPC IPC(8): A61K8/9789A61K8/92A61Q19/02A61Q19/08A61Q17/04A61P17/00A61P17/08
CPCA61K8/9789A61K8/922A61Q19/02A61Q19/08A61Q17/04A61P17/00A61P17/08A61K2800/782A61K2800/592Y02A50/30
Inventor 李玉叶王睿睿
Owner KUNMING MEDICAL UNIVERSITY
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