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Bioabsorbable magnesium alloy stent and preparation method thereof

A magnesium alloy stent and magnesium alloy technology, applied in the field of bioabsorbable magnesium alloy stent and its preparation, can solve problems such as substrate damage and pitting corrosion

Inactive Publication Date: 2021-11-26
苏州脉悦医疗科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Inhomogeneous surface topography can initiate pitting (localized corrosion), while accelerated corrosion can cause serious damage to the substrate

Method used

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  • Bioabsorbable magnesium alloy stent and preparation method thereof
  • Bioabsorbable magnesium alloy stent and preparation method thereof
  • Bioabsorbable magnesium alloy stent and preparation method thereof

Examples

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Embodiment 1

[0039]The stent body immersed in the electrolyte is placed on the anode, and the metal plate is used as the cathode, and the two are connected through a DC power supply, and the surface of the stent body of the anode is ground and processed into any size by applying an external voltage. In order to achieve the stabilization of the viscous layer in the applied voltage, the temperature was controlled at a fixed temperature while stirring the electrolyte. In addition, in order to suppress the generation of air bubbles at the cathode, appropriate voltage application and cut-off operations should be repeated. In addition, air bubbles dissociated from the cathode will cause poor surface accuracy if they adhere to the holder body. As a result, through this electrolytic polishing, an outer diameter of 1.8 mm, a length of 18 mm, a thickness of 120 μm, and a surface area of ​​103.8 mm were fabricated. 2 , Weight 5mg, Ra0.04±0.01μm core structure. In addition, the Ra of the stent body ...

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Abstract

The invention provides a bioabsorbable magnesium alloy stent and a preparation method thereof, and belongs to the technical field of biological stent materials. The magnesium alloy stent comprises a base material, an anti-corrosion layer covering the surface of the base material and a coating layer coating the surface of the anti-corrosion layer, and the anti-corrosion layer is obtained by conducting fluorination treatment on the surface of the base material. The preparation method comprises the following steps of carrying out electrolytic grinding treatment on the base material to obtain a base material with a mirror surface shape, putting the obtained base material into a hydrofluoric acid aqueous solution to obtain a stent coated with the anti-corrosion layer, and then spraying a biodegradable polymer and an endangium thickening inhibitor on the obtained stent to obtain the magnesium alloy stent.

Description

technical field [0001] The invention belongs to the technical field of biological support materials, in particular to a bioabsorbable magnesium alloy support and a preparation method thereof. Background technique [0002] Ischemic heart disease (myocardial infarction, angina pectoris, etc.) caused by coronary artery stenosis and blockage is a serious disease that hinders myocardial blood supply (nutrition, oxygen, etc.), and has become the number one cause of death in the world. In my country, with the continuous improvement of domestic living standards, cardiovascular diseases account for more than 40% of the residents' death from diseases, ranking first, higher than tumors and other diseases. As a means of treating this disease, in recent years, a low-invasive surgical method using a catheter (percutaneous coronary angioplasty) has been widely used, replacing surgical operations requiring chest incision (coronary artery bypass grafting). Among them, coronary artery stent ...

Claims

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Application Information

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IPC IPC(8): A61L31/02A61L31/08A61L31/10A61L31/14A61L31/16A61F2/82
CPCA61F2/82A61L31/022A61L31/088A61L31/10A61L31/16A61L31/148A61F2310/00041A61F2210/0004A61L2420/08A61L2300/416A61L2300/608
Inventor 吕林海吕佑运
Owner 苏州脉悦医疗科技有限公司
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