Rapid gene screening method and device

Abstract

The invention relates to a rapid gene screening method and device. The method comprises the following steps: collecting a to-be-detected sample of a patient through a micro-fluidic chip, wherein the to-be-detected sample comprises a whole blood or saliva or nasopharyngeal swab or wound swab sample of the patient; splitting and amplifying the to-be-detected sample in the micro-fluidic chip to obtain amplified DNA or RNA chains; fusing a biosensor chip which is provided with a probe capable of being bound with a specific DNA or RNA chain and has impedance which is changed violently before and after binding with amplification liquid; inputting an electric signal into the biosensor chip; detecting an output end signal; judging whether the DNA or RNA chain matched with the probe exists in the to-be-detected sample of the patient or not; and replacing the probe to detect whether different DNA or RNA chains exist or not. A worker only needs to collect the to-be-detected sample of the patient, select the probe and configure simple parameters, so that the operation is simple, DNA or RNA extraction and purification do not need to be carried out on the to-be-detected sample, and the detection efficiency is greatly improved.

Description

technical field [0001] This application relates to the technical field of precision medicine, in particular to a method and device for rapid genetic screening. Background technique [0002] Precision medicine is an emerging method of disease prevention and treatment that takes into account differences in personal genes, environment and living habits. It is based on individualized medicine, with the rapid advancement of genome sequencing technology and the intersection of bioinformatics and big data science A new medical concept and medical model developed by the application of medicine. Its essence is to analyze, identify, verify and apply biomarkers for large sample populations and specific disease types through omics technologies such as genomes and proteomics and medical frontier technologies, so as to accurately find the cause of the disease and the target of treatment , and accurately classify the different states and processes of a disease, and finally achieve the pur...

AI Technical Summary

Problems solved by technology

[0004] This application provides a method and device for rapid genetic screening to solve the problem that in the prior art, the genetic testing process is complex and needs to be carried out by professionals in professional institutions, resulting in a long testing cycle, increasing testing costs for doctors and patients, and delaying treatment. The problem

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