Degradable magnesium mesh for 3D printing personalized alveolar bone defect reconstruction

A 3D printing, alveolar bone technology, applied in 3D printing, skull, application, etc., can solve the problems of mesh distortion on the surface of magnesium mesh, damage to the mechanical properties of magnesium mesh, and affect the degradation performance of magnesium mesh, so as to solve stress shielding, Excellent self-supporting effect, the effect of improving the success rate of surgery

Pending Publication Date: 2022-03-01
SHANGHAI JIAO TONG UNIV +1
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] However, due to the characteristics of flammability and oxidation of magnesium alloys, there will be a greater safety risk in the 3D printing of magnesium alloys. At the same time, magnesium alloys also have the characteristics of low boiling point and high vapor pressure, which will lead to serious damage during the 3D printing process. Powder splashing, coupled with the limitation of the preparation accuracy of 3D printing, makes the surface mesh of the prepared magnesium mesh often distorted or blocked. These defects seriously damage the mechanical properties of the magnesium mesh and easily cause local corrosion and affect the degradation performance of the magnesium mesh. , so the application of 3D printed magnesium mesh in alveolar bone defect reconstruction is severely restricted

Method used

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  • Degradable magnesium mesh for 3D printing personalized alveolar bone defect reconstruction
  • Degradable magnesium mesh for 3D printing personalized alveolar bone defect reconstruction
  • Degradable magnesium mesh for 3D printing personalized alveolar bone defect reconstruction

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0049] Embodiment 1, design and preparation of different mesh structure magnesium nets

[0050] Using 3-matic12.0 software (Materialise, Belgium) to design five support nets with different pore structures, the mesh structures are triangle, quadrilateral, hexagon, circle, and honeycomb circle, and the maximum mesh size is 2mm. Due to the specific structure of the personalized magnesium mesh, it is not easy to measure its mechanical properties, so the flat mesh is used as an equivalent replacement here. According to the national standard GB / T 232-2010 metal material bending test method, the standard test of the flat mesh is designed The length and width of the sample are 40mm and 20mm respectively, and the thickness is designed to be 0.4mm. It is prepared by laser powder bed melting technology, and the material used is Mg-3wt.%Nd-0.2wt.%Zn-0.5wt.%Zr magnesium alloy material .

[0051] The three-dimensional model of the flat screen sample and the corresponding printed physical...

Embodiment 2

[0052] Embodiment 2, the mechanical property test of magnesium mesh with different mesh structures

[0053] According to the GB / T 232-2010 bending standard, the flat magnesium mesh with different hole structures prepared in this example 1 was subjected to a mechanical bending test using a universal testing machine, and the applied load was perpendicular to the flat mesh at a rate of 1 mm / min. , until the magnesium mesh sample is destroyed.

[0054] Record the load (N) and real-time beam displacement (mm) of the magnesium mesh sample to obtain the load-displacement curve, and use the formula to calculate the flexural strength and flexural stiffness of the magnesium mesh sample. The data results are shown in Table 1. It can be seen that the magnesium mesh with hexagonal mesh and circular mesh has the greatest bending strength and flexural stiffness; while the magnesium mesh with triangular and honeycomb circular mesh has the worst bending mechanical properties. Considering th...

Embodiment 3

[0057] Embodiment 3, design and preparation of regular hexagonal mesh pure magnesium mesh

[0058] This embodiment relates to a degradable magnesium mesh used for alveolar bone defect reconstruction, figure 2 (a) is a schematic diagram of the overall structure of this embodiment, including an alveolar bone 1 and a magnesium mesh 2, the surface of the alveolar bone 1 has a bone defect, the magnesium mesh 2 completely covers the bone defect, and the magnesium mesh The surface of 2 is provided with evenly distributed mesh holes 3, and the magnesium mesh 2 is connected and fixed to the alveolar bone 1 through the fixing holes 4 and fixing screws 5 opened at the bottom. figure 2 (b) is a schematic diagram of the structure of the magnesium mesh.

[0059] The length of the magnesium mesh is 100mm, the height is 15mm, and the thickness is 0.5mm. The mesh is a regular hexagon with an aperture of 1000 μm. The fixing hole is circular with an aperture of 3mm. The magnesium mesh and f...

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Abstract

The invention discloses a degradable magnesium mesh for 3D printing personalized alveolar bone defect reconstruction. According to the magnesium mesh, a personalized model structure is designed according to CT data, high-precision preparation of the magnesium mesh is achieved through the 3D printing technology, and the magnesium mesh is made to be tightly attached to the anatomical appearance of the alveolar bone; the defects that a traditional titanium mesh needs to be bent in an operation and the postoperative exposure rate is high are overcome, the operation difficulty and time are reduced, and the operation success rate is increased. The surface of the magnesium mesh is of a completely-perforated regular hexagon structure, and the mesh structure has the advantages of self-supporting, easiness in forming, high printing precision, good mechanical property and the like. Meanwhile, by combining the degradability of a magnesium material and the advantage of promoting osteogenesis through bone induction of magnesium ions, the problems that a titanium mesh shields stress and cannot be degraded, and secondary operation is needed for taking out the titanium mesh during tooth implantation are solved. The preparation process is simple, the preparation period is short, raw material loss is small, repeatability is high, pollution is avoided, and the prepared magnesium mesh has the advantages of being controllable in appearance and high in precision and can serve as a new generation of oral cavity alveolar bone large-area bone defect repairing support.

Description

technical field [0001] The invention belongs to the technical field of preparation of biomedical materials, and relates to a degradable magnesium mesh for reconstruction of individualized alveolar bone defects using 3D printing; especially relates to a self-supporting, easy-to-shape, high-printing accuracy and Personalized degradable magnesium mesh for alveolar bone defect reconstruction with good mechanical properties. Background technique [0002] For clinical dentistry, the treatment of large jaw defects has always been a difficult problem for dental implantologists. Insufficient bone mass at the implant site affects the indications for implant treatment, implant quality, functional load, implant aesthetics, and effective survival time of the implant in the oral cavity. Therefore, it is necessary to increase the bone height and bone width of the bone defect by means of bone regeneration. Commonly used bone augmentation techniques include autologous bone grafting, distra...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61F2/28A61F2/30A61L27/56A61L27/50A61L27/04A61L27/32B22F3/105B22F5/10B33Y10/00B33Y80/00
CPCA61F2/2875A61F2/30942B22F5/10B33Y10/00B33Y80/00A61L27/56A61L27/50A61L27/047A61L27/32A61L2430/02A61F2002/2889A61F2002/30948A61F2002/30985A61F2002/3097A61F2002/2835
Inventor 袁广银王银川彭京平王超
Owner SHANGHAI JIAO TONG UNIV
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