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Devices and methods provide for ablation of cardiac tissue for treating cardiac arrhythmias such as atrial fibrillation. Although the devices and methods are often be used to ablate epicardial tissue in the vicinity of at least one pulmonary vein, various embodiments may be used to ablate other cardiac tissues in other locations on a heart. Devices generally include at least one tissue contacting member for contacting epicardial tissue and securing the ablation device to the epicardial tissue, and at least one ablation member for ablating the tissue. Various embodiments include features, such as suction apertures, which enable the device to attach to the epicardial surface with sufficient strength to allow the tissue to be stabilized via the device. For example, some embodiments may be used to stabilize a beating heart to enable a beating heart ablation procedure. Many of the devices may be introduced into a patient via minimally invasive introducer devices and the like. Although devices and methods of the invention may be used to ablate epicardial tissue to treat atrial fibrillation, they may also be used in veterinary or research contexts, to treat various heart conditions other than atrial fibrillation and/or to ablate cardiac tissue other than the epicardium.

The invention discloses an aortic valve stent (100) capable of preventing perivalvular leakage. The aortic valve stent (100) capable of preventing perivalvular leakage comprises a stent (110) and an artificial valve (104), wherein the stent (110) is composed of a plurality of grid cells (112); the artificial valve (104) is connected to the grid cells (112); a sealing unit (106) is arranged at the bottom of the stent (110); the sealing unit (106) is made from a metal memory material and laminated; in a natural state, the sealing unit (106) is arched outwards along the axial direction of the stent and of an annular structure along the peripheral direction of the stent (110); one end of the sealing unit (106) is free and is a free end (116); the other end of the sealing unit (106) is fixed with the bottom of the stent (110) by a fixing element, and is a fixed end (126); when the sealing unit (106) is compressed to enter a sheathing canal, the free end (116) of the sealing unit (106) turns towards the bottom end of the stent and around the fixed end (126), thus the sealing unit (106) is not superposed with the stent (110).

The invention discloses a combination used for preventing and treating newborn piglet diarrhea and a preparation method and application thereof. In percent by weight, the product comprises 88-98% of attapulgite ultra-fine powder, 0.1-3% of organic acid, 0.1-4% of probiotic, 0.05-2% of oligosaccharide, 0.05-1.5% of vitamin C and 0.15-3% of crane sugar. The combination disclosed by the invention isdiluted into solution with the mass fraction of 0.05-3% with drinking water, the solution is used for feeding a piglet in an oral or drinking water manner, and the newborn piglet diarrhea caused by multiple factors can be effectively prevented and treated, thus the combination has the effects of improving immunocompetence of the piglet, improving antioxidant function, regulating intestinal microecology and protecting intestinal shape and can improve survival rate of the piglet, improve production performance of the piglet and relieve weaned stress on the piglet. The combination disclosed by the invention also has the characteristics of simple and convenient application mode, high efficiency, available raw materials, simple preparation and the like.

A grip-aid gripping bandage adopted to be disposed over a finger or glove to protect the finger when using sports equipment or a hand tool and to provide enhanced control when using the sports equipment or hand tool. A first self-adhering strip is provided having a first predetermined length. A second non-self-adhering cushioning strip overlies a portion of and is bonded to the surface of the first self-adhering strip. The entire bandage, including the first self-adhering strip and the second non-self-adhering cushioning strip, provides protection from abrasion and pressure when the bandage is applied to a finger. In a further embodiment, an insert is disposed between the first self-adhering strip and the second non-self-adhering cushioning strip for enhanced protection for the finger.

The invention provides methods for the treatment of cancer in a subject using piperlongumine and/or piperlongumine analogs.

The invention relates to a bamboo middle-density fiber plate, made from bamboo and Japanese cedar, wherein it is formed by 50-95 Japanese cedar sheets, 1-100 bamboo sheets, 8-15 urea-formaldehyde glue, 0.5-5 anti-fungus agent, 0.2-3 solidifier, and 1-3 ceresin wax. And its preparation comprises that: putting bamboo sheets into solution while NaOH is 1-5% of bamboo weight; at 80-130Deg. C and 0.5MPa pressure, boiling it for 10-15min, to be mixed with Japanese cedar sheets, to be grinded and dried; plating urea-formaldehyde glue added with anti-fungus agent, solidifier and wax emulsion on the fiber to be thermally compressed.

The invention relates to a bamboo middle-density fiber plate, made from bamboo and Japanese cedar, wherein it is formed by 50-95 Japanese cedar sheets, 5-50 bamboo sheets, 8-15 urea-formaldehyde glue, 0.5-5 anti-fungus agent, 0.2-3 solidifier, and 1-3 ceresin wax. And its preparation comprises that: putting bamboo sheets into solution while NaOH is 1-5% of bamboo weight; at 80-130Deg. C and 0.5MPa pressure, boiling it for 10-15min, to be mixed with Japanese cedar sheets, to be grinded and dried; plating urea-formaldehyde glue added with anti-fungus agent, solidifier and wax emulsion on the fiber to be thermally compressed.

New photoresists for use during the production of semiconductor and MEMS devices are provided. The primer layer preferably comprises a silane dissolved or dispersed in a solvent system. The photoresist layer includes a first polymer prepared from a styrene and an acrylonitrile, and a second polymer comprising epoxy-containing monomers (and preferably phenolic-containing monomers). The photoresist layer comprises a photoacid generator, and is preferably negative-acting.

A CMOS image sensor according to the present invention includes a substrate having a light receiving region, an interlayer insulating film formed on the substrate, a plurality of metal wirings formed on the interlayer insulating film so as to expose the light receiving region, a protection layer coated on the metal wirings and the interlayer insulating film, and a plurality of color filters formed on the protection layer, wherein at least one of the color filters is provided with an isolation layer formed on an upper surface thereof.

The invention discloses a vecuronium bromide liposome injection and a preparation method thereof. The liposome injection is prepared from vecuronium bromide, cholesterol, phosphatidyl ethanolamine, soyabean lecithin, twain 80, trehalose, mannitol and polyvinylpyrrolidone in a specific weight ratio. The liposome injection has high preparation stability, and the liposome is not cracked due to fusion, ice crystals and the like in the refrigerating process and keeps high entrapment efficiency even after being stored for a long-time. Due to the adoption of the injection, the solubility of the vecuronium bromide is improved, the quality of a preparation product is improved, toxic and side effects are reduced, the retention time of a medicament is increased during systemic circulation, the bioavailability of the medicament is enhanced, the curative effect is improved remarkably; and moreover, the preparation method is simple and is suitable for industrial production.

A hand pad, for protecting an area between four fingers and a palm of the hand. The hand pad is formed with one or more finger openings disposed in the hand pad to accommodate the four fingers of the hand, and with a hand opening in the hand pad aligned with the four finger openings and disposed to accommodate the palm of the hand.

A positive electrode active material has an average particle diameter of 4.5 to 15.5 μm and a specific surface area of 0.13 to 0.80 m²/g. A positive electrode mixture layer contains at least one of a silane coupling agent and/or at least one of aluminum, titanium, or zirconium based coupling agent having an alkyl or an alkoxy groups having 1 to 18 carbon atoms at a content of 0.003% by mass or more and 5% by mass or less with respect to the mass of the positive electrode active material. The nonaqueous electrolyte contains a 1,3-dioxane derivative at a content of 0.05% by mass or more with respect to the total mass of the nonaqueous electrolyte. Thus a nonaqueous secondary battery that has good high-temperature cycle characteristics and suppresses an increase in self-discharge after repetition of charge and discharge cycles at high temperature is provided.

A neurosurgical ultrasonic focusing assisted three-stage atomization cooling and postoperative wound film forming device has a transducer housing and a nozzle, wherein a horn is arranged in the transducer housing, at least two layers of piezoelectric ceramic sheets are arranged at the top of the horn, an electrode sheet connected with an ultrasonic generator is arranged between two adjacent layers of piezoelectric ceramic sheets, the bottom of the transducer housing is of a hemispherical structure, and a plurality of piezoelectric elements connected with the ultrasonic generator are arranged inside the hemispherical structure; and the nozzle is arranged at the bottom of the horn and connected with a medical nanofluid storage cup, compressed gas can also be introduced into the nozzle, and an electrode is also arranged inside the nozzle.

The invention provides a bone marrow specimen processing method, a decalcification solution, and applications. The bone marrow specimen processing method comprises following processing steps of bone marrow tissues: fixing and primary decalcification, dehydration, paraffin embedding, rough trimming, secondary decalcification, and slicing; the decalcification solution at least comprises formic acid,formaldehyde, and distilled water at a volume ratio of 198-202:48-52:190-210, wherein the mass concentration of formic acid ranges from 97 to 99%. The bone marrow specimen processing method is used for processing bone marrow specimen, so that slices with relatively complete tissue structures and clear cell structures can be obtained, and it is beneficial for observation of slices under microscopes.

The invention discloses a degradable magnesium mesh for 3D printing personalized alveolar bone defect reconstruction. According to the magnesium mesh, a personalized model structure is designed according to CT data, high-precision preparation of the magnesium mesh is achieved through the 3D printing technology, and the magnesium mesh is made to be tightly attached to the anatomical appearance of the alveolar bone; the defects that a traditional titanium mesh needs to be bent in an operation and the postoperative exposure rate is high are overcome, the operation difficulty and time are reduced, and the operation success rate is increased. The surface of the magnesium mesh is of a completely-perforated regular hexagon structure, and the mesh structure has the advantages of self-supporting, easiness in forming, high printing precision, good mechanical property and the like. Meanwhile, by combining the degradability of a magnesium material and the advantage of promoting osteogenesis through bone induction of magnesium ions, the problems that a titanium mesh shields stress and cannot be degraded, and secondary operation is needed for taking out the titanium mesh during tooth implantation are solved. The preparation process is simple, the preparation period is short, raw material loss is small, repeatability is high, pollution is avoided, and the prepared magnesium mesh has the advantages of being controllable in appearance and high in precision and can serve as a new generation of oral cavity alveolar bone large-area bone defect repairing support.

The invention discloses an irinotecan hydrochloride lipid nanoparticles injection and a preparation method thereof. Mixed phase is formed by dissolving irinotecan hydrochloride and stearic acid in organic solvent and dissolving lecithin in buffer salt solution; aqueous solution of PEG (polyethylene glycol) 400, glycerol and trehalose is adopted as aqueous phase; and then irinotecan hydrochloride is loaded in lipid nanoparticles by combining stirring emulsification and high-pressure emulsion homogenizing to obtain the irinotecan hydrochloride lipid nanoparticles injection. The inventive lipid nanoparticles preparation has the advantages of high drug loading rate, uniform particle size, long drug retention time in blood circulation, better sustained-release and controlled-release effect, simple preparation method and device, easy operation, improved product quality, reduced toxic and side effects, and suitability for industrialized production.

The invention discloses a dexamethasone acetate tablet and a preparation method thereof. The dexamethasone acetate tablet is prepared from the following raw materials in percentage by weight: 0.62% ofdexamethasone acetate, 68.00% of corn starch, 29.56% of sucrose, 0.99% of carboxymethyl starch sodium, 0.74% of magnesium stearate, and 0.09% of lauryl sodium sulfate. The preparation method of the dexamethasone acetate tablet includes the following steps that micronization treatment of the dexamethasone acetate is realized firstly through the wall breaking of the raw materials, the obtained dexamethasone acetate is fully mixed with the corn starch raw materials to improve dissolution of the tablet, at the same time, when the dexamethasone acetate is integrated with the corn starch during preparation, an overall shape is protected, overall efficacy being not prone to being losing is protected, it is ensured that the appearance of the tablet is complete and smooth with uniform color, moisture content is less than or equal to 5.0%, the content is 93.0-107.0%, and brittleness is less than or equal to 0.8%.