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Ultraviolet absorbing composition with high absorbance

A technology with high absorbency and ultraviolet rays, which is applied in the direction of medical preparations containing active ingredients, skin care preparations, cosmetics, etc., can solve problems affecting product performance, achieve good light stability, reduce damage, and improve UV resistance. Effect

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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Usually, the concentration of UV absorber is directly proportional to the absorbance, however, the excessive addition of UV absorber will affect other properties of the product to varying degrees
For example, UV absorbers used in cosmetics have different degrees of irritation, and different UV absorbers have a maximum dosage limit in cosmetics. The purpose of reducing irritation can only be achieved by reducing the amount of sunscreen added in the formula as much as possible

Method used

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  • Ultraviolet absorbing composition with high absorbance
  • Ultraviolet absorbing composition with high absorbance
  • Ultraviolet absorbing composition with high absorbance

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0048] Preparation of ellagic acid powder solution: Weigh 40mg of ellagic acid and dissolve it in 25ml of ethanol. The solution is turbid. Then, shake it with ultrasonic waves. Take 1mL of turbid solution and dilute it 10 times with ethanol. The solution is clear and the concentration is 0.16mg / mL of ellagic acid powder solution;

[0049] Ethylhexyl salicylate: first take 10uL ethylhexyl salicylate stock solution in 10mL ethanol solution, dissolve and shake well for later use, take 200uL of the above dilution in 5mL ethanol, shake well, measure the absorbance (see figure 1 , ethylhexyl salicylate);

[0050] Ellagic acid + ethylhexyl salicylate: Take 200uL of the above ethylhexyl salicylate dilution in 5mL ethanol, shake well, add 200uL ellagic acid solution (0.16mg / mL), shake well, measure the absorbance (See figure 1 , ethylhexyl salicylate + ellagic acid).

[0051] Depend on figure 1 It can be seen that the absorbance of ethylhexyl salicylate at 210nm wavelength is 2.7,...

Embodiment 2

[0054] Homosalate: Take 10 μL of homosalate in 10 mL of ethanol solution, dissolve and shake well for later use, take 200 μL of this solution in 5 mL of ethanol, shake well, and measure the absorbance (see figure 2 , homosalate);

[0055] Homosalate + ellagic acid powder: Take 200 μL of the above homosalate dilution in 5 mL of ethanol, shake well, add 200 μL of ellagic acid powder solution (0.16 mg / mL), shake well, measure the absorbance (see figure 2 , homosalate + ellagic acid).

[0056] Depend on figure 2 It can be seen that the absorbance of homosalate is 3.0 at a wavelength of 210nm, and the absorbance of the mixture of ellagic acid and homosalate is 10.5; the absorbance of homosalate at a wavelength of 235nm is 3.5, and that of ellagic acid and The absorbance of the ester mixture was 5.5; the absorbance of homosalate at a wavelength of 310 nm was 1.5, and the absorbance of the mixture of ellagic acid and homosalate was 1.6.

[0057] When it is applied to cosmetics,...

Embodiment 3

[0059] Ethylhexyl methoxycinnamate: Take 10 μL ethylhexyl methoxycinnamate in 10 mL ethanol solution, dissolve and shake well for later use, take 200 μL of this solution in 5 mL ethanol, shake well, measure the absorbance (see image 3 , ethylhexyl methoxycinnamate);

[0060] Ethylhexyl methoxycinnamate + ellagic acid: Take 200 μL of the ethylhexyl methoxycinnamate dilution in 5 mL ethanol, shake well, add 200 μL ellagic acid powder solution (0.16 mg / mL), Shake well and measure the absorbance (see image 3 , ethylhexyl methoxycinnamate + ellagic acid powder).

[0061] Depend on image 3 It can be seen that the absorbance of ethylhexyl methoxycinnamate at a wavelength of 310nm is 4.5, and the absorbance of the mixture of ellagic acid and ethylhexyl methoxycinnamate is 5.6.

[0062] When it is applied to cosmetics, the mass ratio of ellagic acid to ethylhexyl methoxycinnamate is 1:6.24, and the concentration of ethylhexyl methoxycinnamate in cosmetics is ≤8.0%.

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Abstract

The invention discloses an ultraviolet absorption composition with high absorbance, and belongs to the technical field of ultraviolet resistance. The ultraviolet absorption composition comprises an ultraviolet absorbent and ellagic acid. Compared with the prior art, the ellagic acid and the ultraviolet light absorber are compounded, so that the ultraviolet resistance of the product can be improved under the condition of the same addition amount of the ultraviolet light absorber, and the product has better light stability and very good popularization and application value.

Description

technical field [0001] The invention relates to the field of anti-ultraviolet rays, and specifically provides an ultraviolet-absorbing composition with high absorbance. Background technique [0002] Ultraviolet rays are one of the most harmful factors to human skin. When irradiated by ultraviolet rays on the skin, a large number of free radicals will be generated, leading to photoaging of the skin, destroying the collagen fibers in the skin tissue, and causing wrinkles and sagging of the skin. Ultraviolet rays can cause damage to the epidermal cells of the skin and affect the normal moisturizing effect of the skin, resulting in dehydrated and dry skin. Ultraviolet rays will accelerate skin pigmentation, make the skin tanned, and produce spots. Excessive exposure to ultraviolet rays will cause skin erythema, skin photosensitivity reactions, and cause allergic reactions such as skin peeling, itching, and rashes. Excessive UV exposure can also lead to conditions such as skin c...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/49A61K8/37A61K8/35A61K8/41A61K8/40A61Q17/04
CPCA61K8/498A61K8/37A61K8/35A61K8/415A61K8/40A61K8/4966A61Q17/04A61K2800/592
Inventor 王煚