24 results about "Skin photosensitivity" patented technology

The invention relates to the technical field of biomedicine, discloses mutant photo-induced ion channel ChR-2 protein, and further discloses a nucleic acid construct, an expression vector, a cell, related application and a computer model. The light-sensitive channel ChR2 protein mutant obtained by the invention has stronger light current, and the light-sensitive capability of the light-sensitive channel ChR2 protein mutant is at least improved by 100 times; besides, the invention also obtains a nucleotide sequence for coding the light-sensitive channel ChR2 protein mutant, constructs a recombinant expression vector, and obtains the light-sensitive channel ChR2 protein with higher expression quantity and stronger light sensitivity, and the light-sensitive channel ChR2 protein is very suitable for expression in cells of mammals (especially human); according to the invention, the rhodopsin in different channels is systematically studied by modifying the position G224 in the helix 6 of seven transmembrane helix motifs, which proves that the mutation of the position G224 in the helix 6 in WT ChR2 accelerates the photosensitivity of the channels, and the considered position is homologous in the helix 6 of the rhodopsin in different channels.

The present application relates to the technical field of biological materials, in particular to a light-responsive drug gel carrier and a preparation method thereof, in order to improve the controlled release function of the hydrogel material, the methyl methacrylate nitrobenzene compound containing nitrobenzene structure, hydantoin structure and propylene structure is prepared first, under the action of a photoinitiator, the double bond is crosslinked with methyl methacrylate and ethylene glycol methacrylate to form a hydrophilic gel network, so that the drug gel carrier is obtained; wherein the nitrobenzene structure has photosensitivity, and the crosslinking structure will be broken under ultraviolet irradiation, thereby reducing the stability of the gel material, destroying the rearrangement of the gel micelle structure, and realizing the release of the loaded drug; and the hydantoin structure introduced in the methyl methacrylate nitrobenzene compound also has good antibacterial performance, which can effectively avoid wound infection and improve wound recovery.

The invention discloses a patterning method for in-situ crosslinking of a ligand on the surface of a single quantum dot, which comprises the following steps of: adding azidoacetic acid molecules or 3-mercaptopropyl acrylate to the surface of the quantum dot as a photo-crosslinking ligand; and then photocrosslinking is carried out on the photosensitive molecules and ligands on the quantum dots under ultraviolet irradiation to change the solubility of the quantum dots. According to the invention, the problem that the photosensitive substances hinder charge transfer between the quantum dots is solved by utilizing crosslinking between the surface ligands on the quantum dots.

The invention discloses a bifunctional molecular group structure for photoresist. The bifunctional molecular group structure comprises a linker, PAG molecules and PDQ molecules. And the linker contains a carbon-oxygen chemical bond or a carbon-nitrogen chemical bond. PAG molecules and PDQ molecules are synthesized on each linker at the same time, wherein the number of the PAG molecules and the number of the PDQ molecules are in proportion, and the total number of the PAG molecules and the PDQ molecules is three or more. And PAG molecules are synthesized on the linker through a carbon-oxygen chemical bond. PDQ molecules are synthesized on the linker through a carbon-nitrogen chemical bond. The invention also discloses a synthesis method of the bifunctional molecular group structure for the photoresist. The invention also discloses a use method of the photoresist adopting the bifunctional molecular group structure. According to the invention, the proportion of PAG molecules to PDQ molecules can be set, so that the uniformity of PAG and PDQ in the photoresist can be ensured, the uniformity and roughness of the line width of the photoresist can be ensured, and different requirements of users on the contrast ratio and light sensitivity of chemical amplification glue can be met at the same time.

The present invention provides a photoresist composition, a preparation method and an application thereof, and a method for forming a photoresist pattern, and specifically relates to the field of photoresist technology. The photoresist composition comprises a poly(p-hydroxystyrene) homopolymer and a photodeactivator, and the mass ratio of the two is 100-600:2-50. The weight average molecular weight of the poly(p-hydroxystyrene) homopolymer is 1000-20000. The photoresist composition has strong photosensitivity, and after exposure by a 248nm deep ultraviolet lithography light source, the exposure dose can be reduced to 10mJ / cm at a film thickness of 500nm. 2 The poly(p-hydroxystyrene) homopolymer has no protective group and can participate in cross-linking, so it has a higher carbon atom content, significantly improves dry etching resistance, improves etching ratio, greatly improves customer production efficiency, and reduces production costs.

The application discloses a fluorescent response type manganese carbonyl carbon monoxide releasing agent, a preparation method and application, wherein the compound has the following structural formula: the manganese carbonyl compound provided by the application has good photosensitivity and fluorescent characteristics, CO release can be accurately controlled through green light, the release process can be tracked in real time by using the change of the fluorescent intensity, and the manganese carbonyl compound is expected to be a photo-triggered carbon monoxide releasing agent with application prospect.

The invention discloses a linearly polarized light detector based on surface acoustic waves, and a preparation method and a detection method thereof, and belongs to the technical field of optical detection. The linearly polarized light detector based on the surface acoustic wave comprises a piezoelectric substrate, wherein a photosensitive layer, an input interdigital transducer and an output interdigital transducer are arranged on the piezoelectric substrate; the input interdigital transducer and the output interdigital transducer are symmetrically arranged on the two sides of the photosensitive layer; wherein the photosensitive layer is of a composite heterojunction structure, and the composite heterojunction structure comprises a metal film layer, a flexible elastomer layer, a two-dimensional anisotropic semiconductor layer and a metal particle layer which are sequentially stacked from bottom to top. On the premise that the complexity and the preparation difficulty of the device are not remarkably increased, the linearly polarized light sensitivity of the two-dimensional anisotropic semiconductor material is effectively enhanced, the dichroism ratio of photo-generated current is improved, and passive and wireless polarization detection of visible light and near-infrared light is achieved.

The invention provides a composite vanadium dioxide nano-particle as well as a preparation method and application thereof. The composite vanadium dioxide nano-particle comprises hollow spherical vanadium dioxide and a tin dioxide coating layer coating the surface of the hollow spherical vanadium dioxide, wherein in the composite vanadium dioxide nanoparticles, the weight content of the tin dioxide coating layer is 1-20%. According to the composite vanadium dioxide nano-particle provided by the invention, the hollow spherical vanadium dioxide is used as an inner core, the tin dioxide is used as a coating layer, and the content of the tin dioxide coating layer is further controlled, so that the obtained composite vanadium dioxide nano-particle has more excellent thermochromic performance, photosensitivity and oxidation resistance; further, the composite vanadium dioxide nano-particles can have a wider application scene in the field of thermochromic materials.

The invention discloses an intelligent device for treating eye diseases, the outer side layer of an eyeshade is made of a graphene superconducting material and has good light transmission and light sensitivity, an eyeshade body absorbs a light source of a light supplement instrument and converts the light source into a light source, light-to-heat treatment is performed on eye skin to open microcirculation, and treatment can be performed during a rest by combining with a massage chair. And secondly, the light source is converted into 600nm red light which can be absorbed by eye feeding light to treat the eyes, so that the purpose of health treatment of the eyes can be integrally achieved during leisure, and the product is simple and exquisite in design, high in practicability and good in effect.

The invention relates to the technical field of eyesight recovery protection devices for ophthalmology patients, particularly discloses an eyesight recovery protection device for ophthalmology patients, and aims to solve the problems that a traditional medical eye pad is inconvenient to use during examination, and light cannot be finely and gradually adjusted to adapt to postoperative photosensitivity. The device is characterized by comprising an eye protector body, a channel unit, a light adjusting unit and a control unit. Wherein the channel unit provides removal-free convenient operation; the light adjusting unit comprises an electrochromic film, and dynamic light transmittance adjustment is achieved; the control unit supports automatic, manual and progressive adaptation modes. By the adoption of the technical scheme, convenient and sanitary eye local operation can be achieved, fine progressive light management is provided, light sensitivity is effectively relieved, eye light adaptability recovery is promoted, and postoperative rehabilitation comfort, safety and efficiency are improved.

The invention provides a light generating system (1000) comprising one or more light generating devices (100), where each of the one or more light generating devices (100) is configured to generate device light (101), where the light generating system (1000) is configured to generate system light (1001) comprising the device light (101) of at least one light generating device (100), wherein the light generating system (1000) is configured to provide the system light (1001) according to the following characteristics (in operating mode): A) during a first time period t1, the system light (1001) is white light having a radiation flux [phi] 11 in a first wavelength range and a radiation flux [phi] 12 in a second wavelength range; (B) during a second time period t2, the system light (1001) is light having a radiation flux [phi] 21 in a first wavelength range and a radiation flux [phi] 22 in a second wavelength range; (C) during a third time period t3, the system light (1001) is light having a radiation flux [phi] 31 in the first wavelength range and a radiation flux [phi] 32 in the second wavelength range; (D) [phi] 21lt; [phi] 11 and [phi] 31 lt; [phi] 11; (E) [phi] 22gt; phi 12 and phi 32 lt; phi 12; (F) t2 is selected from the range of 1 second to 30 minutes; and t1gt; t2; and (G) the first wavelength range is 380 nm-[lambda] 1, and the second wavelength range is [lambda] 1-780 nm, where [lambda] 1 is selected from the range of 485-550 nm.

The invention relates to the technical field of biochemistry, in particular to a light-operated nitric oxide donor with strong fluorescence recovery as well as a preparation method and application of the light-operated nitric oxide donor. According to the light-operated nitric oxide donor with strong fluorescence recovery and the preparation method of the light-operated nitric oxide donor, the donor has good light sensitivity, light stability and anti-interference capacity under ultraviolet irradiation, and accurate control over nitric oxide released by the donor in time and space can be achieved. Meanwhile, the donor is subjected to fluorescence quenching, but the fluorescence intensity is greatly improved by about 110 times after ultraviolet irradiation, accurate synchronization of NO release and detection is achieved, NO with extremely low concentration can also be detected, the method is suitable for real-time monitoring of trace NO in organisms, and the method is low in raw material cost, simple in synthesis step and high in yield. The compound can be used for preparing medicines or related medicines for treating cardiovascular diseases, Alzheimer's disease, inflammation, tumors and neurodegenerative diseases.

The invention belongs to the technical field of gel preparations, and particularly relates to a chitosan photosensitive hydrogel, a drug-loaded photosensitive hydrogel and a preparation method and application of the chitosan photosensitive hydrogel and the drug-loaded photosensitive hydrogel. The invention provides a chitosan photosensitive hydrogel. The chitosan photosensitive hydrogel comprises a chitosan-photosensitizer cross-linked substance and water, the photosensitizer is a tetra-p-phenylamino porphyrin compound. According to the chitosan photosensitive hydrogel provided by the invention, chitosan is used as a hydrogel framework material, a tetra-p-phenylamino porphyrin compound is used as a photosensitizer, a novel photodynamic hydrogel network is constructed, and the obtained chitosan photosensitive hydrogel takes elasticity as a leading material, has relatively good temperature sensitivity and light sensitivity, and can be used for preparing a photodynamic hydrogel. The compound can be used as a chemotherapy drug carrier, realizes combined treatment of a photodynamic therapy and a chemotherapy, realizes an efficient combined anticancer effect, improves a curative effect, reduces toxicity, and provides a new idea for construction and application of a photodynamic-chemotherapy anticancer drug system.

Provided in the present application are a new photosensitive channel protein VR2.0 and the use thereof. The photosensitive channel protein VR2.0 series provided in the present application has a significant therapeutic effect in the treatment of retinal photoreceptor degenerative diseases. The new photosensitive channel protein has a higher photosensitivity, fast kinetics and low side effects. Under the same light stimulation conditions, the new photosensitive channel protein has a relatively fast response frequency and can maintain a stable current signal during high-frequency responses. The present application provides a better choice for the development of optogenetic therapy for retinal photoreceptor degenerative diseases and has an important application and popularization value.

The disclosed and claimed subject matter relates to a method for depositing a tin-containing film. The method includes: (i) contacting a substrate with a vapor of an organotin precursor in a deposition reactor, (ii) purging the reaction vessel with an inert gas, (iii) contacting the substrate with a vapor containing water vapor to form a layer of an organotin oxygen network, (iv) purging the reaction vessel with an inert gas, (v) contacting the substrate with a vapor containing a carboxylic acid, and (vi) purging the reaction vessel with an inert gas.

The present invention provides compositions and kits comprising at least one nucleic acid or polypeptide molecule encoding a mutant CoChop protein. The methods of the invention comprise administering to a subject a composition comprising a mutant CoChop to protect, improve, or restore light transduction. Preferably, the compositions and methods of the invention are provided to a subject with visual impairment to restore vision to a normal level.

The utility model relates to the technical field of chips, and discloses a chip anti-interference structure which is suitable for a chip body, the chip body is provided with a photosensitive area, the chip body is provided with a covering layer, and the covering layer is located on the periphery of the photosensitive area and used for covering a non-photosensitive area of the chip body. According to the anti-interference structure of the chip, the covering layer is arranged on the chip body, so that the thickness of the whole chip is greatly increased, and the overall strength of the chip is effectively improved; the digital analog circuit on the non-photosensitive area of the chip body is shielded by the covering layer, the covering layer isolates the non-photosensitive area in the chip body from being in contact with ambient light, the parasitic light sensitivity of the chip body is reduced, the digital analog circuit is prevented from being interfered and generating wrong electronic noise, and therefore the signal quality and the performance stability of a device are improved.

The invention discloses a polyimide positive photoresist based on an acid deactivation mechanism, which comprises the following components in percentage by weight: 10-50% of polyamic acid resin, 10-50% of acid catalyst, 10-50% of photoinduced deactivator and 10-50% of solvent. 0.5%-10% of an acidic catalyst; 0.5%-10% of a photoinduced deactivating agent; and 50%-90% of a solvent. The invention provides a polyimide positive photoresist based on an acid deactivation mechanism, the photoresist belongs to a chemical amplification photoresist, the photosensitivity is strong, the exposure dose can be reduced to 50-70mj / cm < 2 > by taking the photoresist thickness of 3 microns as an example, meanwhile, the imidization photoresist thickness loss is smaller, the production efficiency can be greatly improved, and the production cost can be reduced.

This invention discloses a surface acoustic wave (SAW)-based linearly polarized light detector, its fabrication method, and detection method, belonging to the field of optical detection technology. The SAW-based linearly polarized light detector includes: a piezoelectric substrate, on which a photosensitive layer, an input interdigital transducer, and an output interdigital transducer are disposed; the input and output interdigital transducers are symmetrically arranged on both sides of the photosensitive layer; wherein, the photosensitive layer is a composite heterojunction structure, the composite heterojunction structure comprising, from bottom to top, a metal thin film layer, a flexible elastomer layer, a two-dimensional anisotropic semiconductor layer, and a metal particle layer stacked sequentially. This invention effectively enhances the linear polarization sensitivity of the two-dimensional anisotropic semiconductor material and improves the dichroism ratio of the photocurrent without significantly increasing device complexity or fabrication difficulty, achieving passive wireless polarization detection of visible and near-infrared light.

The invention provides a light-sensitive antibacterial gel for women and a preparation method thereof. The gel comprises a water-soluble polyurethane base material, a photosensitizer and various natural extracts such as chrysanthellum indicum, radix sophorae flavescentis, propolis and a pelargonium graveolens extract. Through the synergistic effect of the photosensitizer and the natural plant extract, the gel can release active oxygen at the focus position and act on the focus position where bacteria gather, the sterilization efficiency is improved, and the symptoms such as leucorrhea increase, peculiar smell and pruritus vulvae caused by bacterial infection are relieved. By matching with antibacterial components such as the radix sophorae flavescentis extract and the propolis extract, the inhibition rate on pathogenic bacteria such as candida albicans and escherichia coli can be greatly improved. In addition, the water-soluble polyurethane base material of the gel can form a protective film on the surface of the vulva skin, isolate external stimulation and avoid inflammation aggravation, the plant extract can quickly relieve scorching hot and pruritus symptoms of the vulva, has antibacterial and anti-inflammatory effects, can relieve red and swollen and inflammatory response of the vulva skin, and improves the use comfort.

The application provides a display panel and a mobile terminal. The light sensing module of the display panel comprises a light sensing transistor and a light condensing structure arranged on the light sensing transistor. The first active layer of the light sensing transistor comprises a first channel portion. The first source-drain electrode layer is arranged on the first active portion on the two sides of the first channel portion. The light condensing structure comprises at least one protrusion protruding in the direction away from the substrate of the display panel. In the plan view direction of the display panel, the light condensing structure covers at least the first channel portion of the first active layer. The light condensing structure is arranged on the light sensing transistor of the light sensing module, so that the light passing through the light condensing structure is focused on the channel portion in the light sensing transistor. The total amount of the light received by the light sensing transistor is increased, and the photosensitivity of the light sensing transistor is improved.

The invention relates to levofloxacin hydrochloride eye drops and a preparation method thereof, and belongs to the technical field of pharmaceutical preparations, in particular to the levofloxacin hydrochloride eye drops which comprise the following components: 0.15-0.55% (w / v) of levofloxacin hydrochloride, 0.01-0.1% (w / v) of preservative, 0.03-0.1% (w / v) of glycine, 0.03-0.1% (w / v) of keratin sulfate, a pH regulator, an isoosmotic adjusting agent and water. According to the levofloxacin hydrochloride eye drops, the defect that levofloxacin hydrochloride is high in light sensitivity is overcome, the problem that levofloxacin hydrochloride is easy to decompose in light is solved, and the levofloxacin hydrochloride eye drops are high in stability and high in safety.

The present invention provides a positive photoresist composition, a preparation method thereof, and an application, relating to the technical field of photoresist preparation, which includes: phenolic resin, crosslinking agent, acidic catalyst, photo deactivator, and optionally a solvent, wherein the photo deactivator includes an anionic initiator. The positive photoresist composition of the present invention belongs to a chemically amplified photoresist. The phenolic resin therein has excellent physical and chemical properties, appropriate dissolution rate, and good film-forming property. In the non-exposed area, the acidic catalyst catalyzes the crosslinking reaction between the crosslinking agent and the phenolic resin. After exposure to ultraviolet light with a wavelength of 365 nm or 436 nm in the exposed area, the compound generated by the anionic initiator will deactivate the acidic catalyst and no longer catalyze the crosslinking reaction. The present invention solves the technical problem that the poor photosensitivity of the photoresist leads to a large demand for exposure dose, and achieves the technical effects of strong photosensitivity of the photoresist, small demand for exposure dose, improved production efficiency, and reduced production cost.