The invention discloses a process for the arsenic removal of 1-hydroxy ethylidene-1,1-diphosphonic acid, which ensures low production cost. The process comprises the following operating steps of: adding 400 to 1,000 weight parts of 1-hydroxy ethylidene-1,1-diphosphonic acid free from arsenic removal treatment into a reaction kettle, introducing vapor to adjust the temperature of the material in the kettle to 20 to 70 DEG C by using a reaction kettle clamping sleeve, adding 0.1 to 1 weight part of phosphorus pentasulfide serving as an arsenic removal agent, adding 0.2 to 2 weight parts of activated carbon, washing a charging hole by using 0.5 to 2 weight parts of pure water after the charging is finished, preserving the heat for 1 to 5 hours at the temperature of 20 to 70 DEG C, filtering the 1-hydroxy ethylidene-1,1-diphosphonic acid (HEDP), heating the filtered clean 1-hydroxy ethylidene-1,1-diphosphonic acid to 80 DEG C, performing external evaporation for 1 to 3 hours under negative pressure, and before the external evaporation is finished, performing activity analysis, adding the pure water for dilution according to an activity result, and introducing cooling water to reduce the temperature of the material in the kettle to 40 to 50 DEG C by using the reaction kettle clamping sleeve and performing discharging.