Cronobacter bacteriophage and application thereof

A technology of Cronobacter and phage, applied in the field of microorganisms, to achieve the effects of good phage source, good acid-base and temperature tolerance, and good stability
CN114540313APending Publication Date: 2022-05-27GUANGDONG INST OF MICROBIOLOGY GUANGDONG DETECTION CENT OF MICROBIOLOGY
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
GUANGDONG INST OF MICROBIOLOGY GUANGDONG DETECTION CENT OF MICROBIOLOGY
Publication Date
2022-05-27

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Abstract

The invention provides a Cronobacter bacteriophage, the Cronobacter bacteriophage is Cronobacter bacteriophage vBCtuPB1, the preservation number of the Cronobacter bacteriophage vBCtuPB1 is GDMCC No: 61185-B1, the Cronobacter bacteriophage is a short-tail bacteriophage, the short-tail bacteriophage is of a polyhedral head and short-tail structure, the head is about 51 mm, and the tail is about 11 mm. The bacteriophage can be used for specifically splitting and splitting the cronobacter malonate and the cronobacter suridatensis. The bacteriophage vBCtuPB1 has good stability in the pH range of 4.0-11 and at the temperature of 25-60 DEG C, does not carry any virulence or antibiotic resistance gene, and can be safely applied to prevention and control of food cronobacter.
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Description

technical field

[0001] The invention belongs to the technical field of microorganisms, and in particular relates to a Cronobacter phage and its application. Background technique

[0002] Cronobacters sakazakii (Cronobacterspp. (Enterobacter sakazakii)) is an important food-borne pathogen that can be infected by people of all ages, especially in premature infants, low birth weight infants or immune-compromised infants. Infant damage can lead to meningitis, bacteremia, and necrotizing enterocolitis, with mortality rates as high as 40 to 80 percent. The International Food and Agriculture Organization and the World Health Organization have listed Cronobacter as a Class A pathogen in infant formula milk powder. There are 7 species of this genus, including C. sakazakii, malonate C. malonaticus and C. turicensis have been reported to cause clinical infection. my country's national food safety standard "GB 10765-2010 National Food Safety Standard Infant Formula" expressly stipulat...

Claims

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