Moisturizing and moistening composition as well as preparation method and application thereof

A composition and moisturizing technology, applied in the direction of pharmaceutical formulations, cosmetic preparations, dressing preparations, etc., can solve the problems of poor water solubility and unstable dispersion of ceramide, so as to improve moisturizing, improve barrier repair, and easily form The effect of fine particles

Pending Publication Date: 2022-06-21
GUANGDONG MARUBI BIOLOGICAL TECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] In order to overcome the deficiencies of the prior art, one of the objectives of the present invention is to provide a moisturizing composition, the composition containing the ceramide component is made into nano-liposomes, so as to solve the problems of poor water solubility and unstable dispersion of ceramide The second purpose of the present invention is to provide a method for preparing a moisturizing composition, which has simple steps and is suitable for large-scale preparation; the third purpose of the present invention is to provide an application of a moisturizing composition, which can be added as a raw material to Widely used in cosmetics

Method used

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  • Moisturizing and moistening composition as well as preparation method and application thereof
  • Moisturizing and moistening composition as well as preparation method and application thereof
  • Moisturizing and moistening composition as well as preparation method and application thereof

Examples

Experimental program
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Effect test

Embodiment 1

[0033] A moisturizing and moisturizing composition, the moisturizing and moisturizing composition is nanoliposome, comprising the following raw materials by weight percentage:

[0034] Oil phase: 1% ceramide, 5% linseed oil, 5% sodium lauroyl lactylate and 2% cholesterol; wherein, ceramide is ceramide 1, ceramide 3 and ceramide in a mass ratio of 1:1:2 6 compound.

[0035] Aqueous Phase: 3% Polyol, 1% Green Tea Extract, 1% Centella Asiatica Extract, 1% Rosemary Extract, 1% Licorice Extract, 1% Polygonum cuspidatum Extract, 1% Scutellariae Extract, 1% Mother chrysanthemum extract, 1% whey protein, the balance is water. Wherein, the polyol is dipropylene glycol and 1,2-hexanediol with a mass ratio of 1:1.

[0036] The preparation method of the above-mentioned moisturizing and moisturizing composition includes the following steps: heating the oil phase and the water phase to 85-90° C. respectively, pouring the oil phase into the water phase while stirring at a speed of 10000 r / ...

Embodiment 2

[0038] A moisturizing and moisturizing composition, the moisturizing and moisturizing composition is nanoliposome, comprising the following raw materials by weight percentage:

[0039] Oil phase: 5% ceramide, 12% baobab seed oil, 5% cetearyl alcohol, 5% cetyl alcohol and 5% cholesterol; wherein, ceramide is a ceramide with a mass ratio of 1:3:3 1. The complex of ceramide 3 and ceramide 6.

[0040] Aqueous Phase: 4% Dipropylene Glycol, 2% Green Tea Extract, 2% Centella Asiatica Extract, 2% Rosemary Extract, 2% Licorice Extract, 1-2% Polygonum cuspidatum Extract, 1-2% Scutellaria baicalensis extract, 1-2% marigold extract, 1-3% hydrogenated lecithin, and the balance is water. Wherein, the polyol is dipropylene glycol and / or 1,2-hexanediol.

[0041] The preparation method of the composition of this example is the same as that of Example 1.

Embodiment 3

[0043] A moisturizing and moisturizing composition, the moisturizing and moisturizing composition is nanoliposome, comprising the following raw materials by weight percentage:

[0044]Oil phase: 4% ceramide, 10% camellia seed oil, 7% sodium lauroyl lactylate and 4% cholesterol; wherein, ceramide is ceramide 1, ceramide 3 and ceramide in a mass ratio of 1:2:2 A complex of amide 6.

[0045] Aqueous Phase: 3.5% Polyol, 1% Green Tea Extract, 2% Centella Asiatica Extract, 2% Rosemary Extract, 1% Licorice Extract, 2% Polygonum cuspidatum Extract, 2% Scutellariae Extract, 2% Mother chrysanthemum extract, 2% whey protein, and the balance is water. Wherein, the polyol is dipropylene glycol and 1,2-hexanediol with a mass ratio of 2:1.

[0046] The preparation method of the composition of this example is the same as that of Example 1.

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Abstract

The invention discloses a moisturizing composition and a preparation method thereof, the composition is a nano-liposome and comprises an oil phase and a water phase, the oil phase comprises ceramide, vegetable oil, an emulsifier and cholesterol; the water phase comprises water, polyol, a plant soothing extract and an emulsifier. According to the composition, in order to solve the problems that ceramide is poor in water solubility and unstable in dispersion, the composition is prepared into nano-liposome, the nano-liposome serves as a carrier, the addition amount of ceramide can be increased, plant soothing extract is further added, and the moisturizing, moistening and barrier repairing effects of the composition can be improved. The composition adopts a high-pressure homogenization method to prepare the liposome, the steps are simple and convenient, the system of the liposome is stable, and the composition is suitable for large-scale production.

Description

technical field [0001] The invention relates to the technical field of ceramide encapsulation, in particular to a moisturizing and moisturizing composition and a preparation method and application thereof. Background technique [0002] As the main component of human epidermis stratum corneum lipids, ceramides together with other lipids constitute the stratum corneum protective barrier between the human body and the external environment. This layer of barrier function mainly includes retaining moisture and protecting against external stimuli. Decreased ceramides in the skin due to aging and other causes impair epidermal barrier function. By using skin care cosmetics containing ceramide active substances, ceramides can be added to the stratum corneum of the skin to achieve multiple skin care functions such as skin barrier repair, water retention, anti-wrinkle and anti-aging. However, ceramides have poor water solubility and are easy to crystallize, which is not conducive to ...

Claims

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Application Information

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IPC IPC(8): A61K8/68A61K8/92A61K8/9789A61K8/63A61K8/34A61K8/14A61Q19/00
CPCA61K8/68A61K8/922A61K8/63A61K8/345A61K8/9789A61K8/14A61Q19/00A61K2800/805A61K2800/5922
Inventor 裴运林聂艳峰林涛蒲艳王娟
Owner GUANGDONG MARUBI BIOLOGICAL TECH CO LTD
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