Unlock instant, AI-driven research and patent intelligence for your innovation.

Water-proof paint for back lining layer of cataplasm

A technology of waterproof coating and backing layer, applied in the field of medicine, can solve the problems of affecting the curative effect of medicines, decrease of the viscosity of preparations, loss of medicine components, etc., to prevent water seepage and loss of medicines, good air permeability and flexibility, and low cost. Effect

Inactive Publication Date: 2005-05-18
SECOND MILITARY MEDICAL UNIV OF THE PEOPLES LIBERATION ARMY
View PDF0 Cites 1 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The backing layer of cataplasms is mostly made of non-woven fabric, which has good air permeability, but it is easily impregnated and penetrated by sweat, water, etc., resulting in the loss of drug ingredients and the decrease of the viscosity of the preparation, which affects the curative effect of the drug.

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0006] Embodiment 1 prepares cataplasma backing layer waterproof coating

[0007] Take 2 g of ethyl cellulose, dissolve it in 20 ml of 95% ethanol, and make a solution with a concentration of 10%. Add 2ml of dibutyl sebacate, mix well, spread on 100cm 2 on a non-woven fabric and let dry. The relative moisture permeability was measured by the weight gain method, and the permeability of the uncoated non-woven fabric was 100%, and the permeability was 14.2%.

Embodiment 2

[0008] Embodiment 2 prepares cataplasma backing layer waterproof coating

[0009] Take 2 g of cellulose acetate, dissolve it in 10 ml of acetone, and make a solution with a concentration of 20%. Add 0.5ml of tributyl citrate, mix well, spread on 100cm 2 on a non-woven fabric and let dry. The relative moisture permeability was measured by the weight gain method, and the permeability of the uncoated non-woven fabric was 100%, and the permeability was 15.6%.

Embodiment 3

[0010] Embodiment 3 prepares cataplasma backing layer waterproof coating

[0011] Take 1.5g of ethylene-vinyl acetate, dissolve it in 30ml of chloroform, and make a solution with a concentration of 5%. Add 0.5ml of pentaerythritol ester, mix evenly, spread on 100cm 2 on a non-woven fabric and let dry. The relative moisture permeability was measured by the weight gain method, and the permeability of the uncoated non-woven fabric was 100%, and the permeability was 18.3%.

[0012] The above results show that the waterproof coating of the present invention has a remarkable waterproof effect and can be used as a waterproof coating for the backing layer of cataplasms or other transdermal preparations.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention relates to the technical field of medicine, and relates to a waterproof coating for the backing layer of cataplasms. It is composed of skeleton material, solvent and plasticizer. The skeleton material is selected from ethyl cellulose, cellulose acetate, cellulose acetate butyrate, ethylene-vinyl acetate copolymer, the solvent is ethanol or acetone, and the plasticizer is selected from phthalate, phosphate, aliphatic Dibasic acid esters, citrates, vegetable oils, polyols. The preparation method of the invention is simple, low in cost and convenient to use, can prevent the loss of medicinal components and decrease in the viscosity of the preparation caused by impregnating the cataplasm with water, sweat, etc., prolong the use time of the cataplasm and improve the curative effect. Can be used as a waterproof coating for the backing layer of poultices or other transdermal preparations.

Description

Technical field: [0001] The invention relates to the technical field of medicine, and relates to a waterproof coating for the backing layer of cataplasms. Background technique: [0002] Catapult refers to the external preparation made by mixing the drug with a suitable hydrophilic matrix and coating it on the backing layer. Because of its large drug loading, good air permeability, low irritation to the skin, and no gasoline and other organic solvents are used in the preparation process, which avoids environmental pollution, it has been increasingly used in the pharmaceutical and cosmetic industries. Wide range of applications. The backing layer of cataplasms is mostly made of non-woven fabric, which has good air permeability, but is easily impregnated and penetrated by sweat, water, etc., resulting in loss of drug components and decreased viscosity of the preparation, etc., which affects the curative effect of the drug. Especially for patients who need to work in high temp...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Patents(China)
IPC IPC(8): C09D5/16C09D101/08C09D123/08
Inventor 胡晋红刘继勇
Owner SECOND MILITARY MEDICAL UNIV OF THE PEOPLES LIBERATION ARMY