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External-use disinfecting medicinal preparation for women

A kind of pharmacy and women's technology, applied in the field of pharmaceuticals, can solve the problems of lack of knowledge about sexual behavior, insufficient rate of medical visits for patients, backward cultural quality and hygienic habits, etc.

Inactive Publication Date: 2005-06-01
陈秀枢
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Due to the large population in our country, the cultural quality and hygiene habits are relatively backward, the knowledge of gynecological health care and healthy sexual behavior is relatively lacking, and the influence and constraints of traditional culture make a large number of patients unable to receive timely treatment. ~30%
Imidazoles (such as ketoconazole, econazole, fluconazole, clotrimazole, etc.), polyenes (such as amphotericin B, nystatin, etc.) are currently effective drugs for the treatment of fungal vaginitis, but their Toxic side effects and high recurrence rate after treatment are also recognized

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0075] Get 8% of raw material p-hydroxybenzoate in weight percentage, 36% of mandelic acid, 30% of lactobacillus, and 26% of oligosaccharides are mixed and prepared as main ingredients for subsequent use; then use 78% of boric acid, 20% of sodium bicarbonate, stearic acid 2% of magnesium is mixed and prepared as auxiliary material; after mixing the prepared main material and auxiliary material in a ratio of 4:1, the vagina effervescent tablet is prepared by the existing method.

Embodiment 2

[0077] Get the raw material paraben 25%, mandelic acid 18%, lactobacillus 23%, oligosaccharide 34% to mix and be prepared as main ingredient standby: water, OP, propylene glycol etc. are prepared by conventional methods to obtain non-ionic surface active The agent is used as a solvent, and the main ingredient is dissolved to be prepared as an external spray with a concentration of 30mg / ml.

Embodiment 3

[0079] Get the raw material paraben 21%, mandelic acid 19%, lactic acid bacterin 26%, oligosaccharide 34% to mix and prepare main ingredient standby; The agent is used as a solvent, and the main ingredient is dissolved to be prepared as an external lotion with a concentration of 25 mg / ml.

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PUM

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Abstract

The invention is a female external use disinfectant. It is characterized in that the main raw materials in the following weight percentages are contained in the components, and prepared into medicaments: 2-40% of parabens, 3-50% of mandelic acid, 10-55% of lactobacillus, and 8-50% of oligosaccharides . The present invention is a compound type novel disinfectant, the antibacterial component in the main component has no obvious toxic and side effects, and its antibacterial effect is mainly to inhibit the activity of respiratory enzymes and electron transfer enzymes in microbial cells, and has the ability to destroy the permeability of microbial membranes. The effect of inhibiting and killing certain microorganisms, and its antibacterial spectrum is characterized by a strong effect on mold and yeast-like fungi. Mandelic acid has a strong activity of killing protozoa such as trichomonas and toxoplasma gondii, and the proliferation efficiency of oligosaccharides on endogenous bifidobacteria can reach 10-100 times higher, which is an indigestible food without any toxic side effects on the human body. Sugars, lactic acid bacteria and oligosaccharides have significant "nutritive effects" as microecological regulators.

Description

technical field [0001] The invention relates to the technical field of medicines, in particular to external disinfectants for women. Background technique [0002] Vaginitis is a frequently-occurring disease in gynecology. From the perspective of etiology, it can be divided into fungal vaginitis, trichomonal vaginitis, and bacterial vaginosis (bacterial vaginosis, BV: previously called non-specific vaginitis, non-specific vaginitis) , NSV), senile vaginitis, gonorrhea, syphilis, etc. Although the first four types of vaginitis are not as serious as gonorrhea and syphilis, they have a high incidence, a long course, and are easy to relapse. It is a common disease that seriously affects the physical and mental health of women. [0003] Fungal vaginitis, trichomonas vaginitis, bacterial vaginosis and senile vaginitis are four common diseases, the common causes of their pathogenesis are: the decline of vaginal local immunity, imbalance of microecological flora, large dose or Long...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A01N63/00A61K35/20A61P15/00
Inventor 陈秀枢
Owner 陈秀枢