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Effective-component extract of Foliun-Mori and its preparation method

A mulberry leaf extract and extract technology are applied in the field of mulberry leaf active ingredient extract and preparation, which can solve the problems of deep color and distance of the extract, and achieve the effects of lowering blood sugar, improving liver and kidney functions, and reducing calories

Inactive Publication Date: 2006-06-21
上海润巍投资管理有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

According to the mulberry leaf extract extracted by the process described in CN1394623A, even if the water extraction and alcohol precipitation extraction process commonly used in traditional Chinese medicine preparations is adopted, the content of γ-aminobutyric acid and nojirimycin in the mulberry leaf extract has increased, but as a food , health care products and pharmaceutical raw materials are still far away, and the color of the extract is dark

Method used

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  • Effective-component extract of Foliun-Mori and its preparation method
  • Effective-component extract of Foliun-Mori and its preparation method
  • Effective-component extract of Foliun-Mori and its preparation method

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0031] The preparation of embodiment 1 mulberry leaf extract

[0032] 10kg of mulberry leaf coarse powder contains 0.12% of gamma-aminobutyric acid and 0.11% of nojirimycin. Add 200L of tap water, stir and heat to 80°C, and sieve through a 40-mesh sieve after one hour. Add 100L of tap water to the mulberry leaves, treat as above, and combine to obtain the filtrate (1), and add alum to the filtrate (1) to make the pH 3-4. Stir for 5 minutes and let it stand for 20-30 minutes, the flocs precipitate out. Filter and concentrate in vacuo to form an extract with a specific gravity of 1.20. Add 2-3 times the volume of 50% ethanol to the extract, so that the ethanol concentration is 50% (v / v), stir evenly and let stand. After the supernatant is clarified, take the supernatant, concentrate in vacuo to contain 10% solids, and spray dry to obtain yellow mulberry leaf extract powder. The yield is 7.5% of the crude drug amount. Method determination, the contents were 1.0% and 1.35%. Th...

Embodiment 2

[0033] The preparation of embodiment 2 effervescent tablets

[0034] Effervescent Tablet Formula:

[0035] Vitamin C 4.5g

[0036] Lactose 120g

[0037] Sodium bicarbonate 290g

[0038] Anhydrous citric acid 380g

[0039] Fruit powder 50g

[0040] Aspartame 88g

[0041] Essence (powder) 5g

[0042] Leucine 20g

[0043] Beta-Carotene 2.5g

[0044] Mulberry Leaf Extract 110g

[0045] Total 1000g

[0046] Preparation:

[0047] Lactose and sodium bicarbonate are mixed and sieved, and mulberry leaf extract and binder are added to make alkaline granules. After drying, it is mixed with anhydrous citric acid, fructose, aspartame and other auxiliary materials, and then compressed into tablets.

Embodiment 3

[0049] biscuit recipe

[0050] Granulated sugar 175g

[0051] Butter 150g

[0052]Egg 150g

[0053] Flour 520g

[0054] Appropriate amount of spices

[0055] Mulberry Leaf Extract 5g

[0056] Total 1000g

[0057] Preparation:

[0058] Soften the butter first, then add sugar and eggs to fully emulsify, then add flour, spices, mulberry leaf extract and evenly form a dough to form the embryo. Divide the raw material into large pieces, use various small molds to buckle or use various nozzles to squeeze into small biscuits, put them in a baking tray, and bake them in an oven at 200°C-220°C.

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Abstract

The invention relates to a mulberry leaf effective ingredient extract and its manufacturing method. The extract is deposited out from the water extracting liquid of the mulberry leaf, and then carries on alcohol sediment; the nojirimycin in it is 1.0-3.0%, gamma-aminobutyric acid 0.8-1.5%. The purity of the extract can be upgraded greatly, the effective ingredient will be upgraded prominently, and it can be applied to product food, healthy keeping product and medicine for reducing blood sugar, controlling blood pressure, and improving the intestinal canal.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicine, in particular to an extract of active ingredients of mulberry leaves and a preparation method thereof. Background technique [0002] Mulberry leaves were first seen in the "Shen Nong's Materia Medica" in the Eastern Han Dynasty. In "Ben Cao Tu Jing", they are called "immortal leaves". Modern pharmaceutical research has pointed out that mulberry leaves contain a variety of functional ingredients. It contains about 0.1% Nojirimycin (DNJ), which can combine with α-glucosidase in the small intestine, thereby inhibiting the decomposition of disaccharides such as maltose and sucrose into glucose, and inhibiting the increase of blood sugar level. Mulberry leaves also contain the functional factor γ-aminobutyric acid, which can not only act as a neurotransmitter, improve brain function, but also have the effect of lowering blood pressure, calming the mind and improving liver and kidney functi...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K31/435A61K31/197A61K36/605A61K9/20A61P3/10A61P9/12A23L1/30C07F7/08C07C229/08C07C227/40G01N30/22A23L33/105A61K31/695
Inventor 仇波栗颍陆韵王建中
Owner 上海润巍投资管理有限公司
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