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Medicine for treating diabetes, and its prepn. method

A technology of medicine and yam, which is applied in the field of Chinese patent medicine for treating diabetes and its preparation, can solve the problems of poor curative effect, large side effects, liver necrosis, etc., and achieve the effect of no toxic side effects and obvious hypoglycemic effect

Active Publication Date: 2007-02-14
SHAANXI KANGHUI PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Thiazolidinedione derivatives drugs, such as rosiglitazone, pioglitazone, and troglitazone, have good hypoglycemic and blood pressure-lowering effects on type II non-insulin-dependent diabetes mellitus (NIDDM), but their side effects Large, especially serious damage to the liver, and even cause liver necrosis, and expensive
However, some known Chinese patent medicines have poor efficacy

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0042] Capsules

[0043] The prescription of the pharmaceutical composition is (in grams): American ginseng 165, astragalus 330, yam 330, rehmannia 330, dogwood 165, medlar 165, Radix radix 110, Anemarrhena 110, Tianhuafen 110, schisandra 110, gallnut 165, Pueraria 110.

[0044] Preparation method: Weigh the required weight of American ginseng, dry it at 80°C, grind it into fine powder, and pass the American ginseng powder through a 80-mesh sieve. Take the other eleven ingredients of the above weight and add 15 times the amount of water to soak for 4 hours, decoct twice, for 1.5 hours for the first time, and 1 hour for the second time, filter, combine the second filtrate, and concentrate at 80°C to a relative For the extract with a density of 1.15-1.20, add ethanol after cooling to make the alcohol content reach 60v / v%, let the alcohol settle for 24 hours, filter, recover ethanol from the filtrate, and concentrate at 80°C to extract with a relative density of 1.15-1.20. past...

Embodiment 2

[0060] tablet

[0061] The prescription of the pharmaceutical composition is (grams): American ginseng 10, astragalus 25, Chinese yam 25, rehmannia glutinosa 25, dogwood 10, medlar 10, Radix Ophiopogon japonicus 6, Anemarrhena 6, Trichosanthes 6, Schisandra chinensis 10, Pueraria 6 composition.

[0062] Preparation method: the same as Example 1, the difference is that the drying temperature of American ginseng is 70°C, and it is passed through a 60-mesh sieve; the concentration temperature of the water extract is 70°C; the alcohol content in the extract reaches 50v / v%, and the alcohol precipitation is allowed to stand for 18 hour, filter; the ethanol recovery is 70 DEG C, and concentrate to the extractum whose relative density is 1.20; extractum is dried at 80 DEG C and carry out normal pressure drying, and the extracted extract powder obtained by crushing is passed through a 60 mesh sieve to obtain extract powder; The above-mentioned American ginseng fine powder is mixed wit...

Embodiment 3

[0064] Granules

[0065] The prescription of the pharmaceutical composition is (grams): American ginseng 25, astragalus 40, Chinese yam 40, rehmannia glutinosa 40, dogwood 25, medlar 25, Ophiopogon japonicus 16, Anemarrhena 16, Tianhuafen 16, schisandra 16, Galla gall 25, Pueraria 16 .

[0066]Preparation method: the same as Example 1, the difference is that the drying temperature of American ginseng is 90°C; American ginseng powder is passed through a 100-mesh sieve; the concentration temperature of the water extract is 90°C; the alcohol content in the extract reaches 70v / v%. Time 32 hours, filter; ethanol recovery temperature is 90°C, and concentrate to the extract with a relative density of 1.15; the extract is dried under reduced pressure at 90°C, crushed and passed through a 100-mesh sieve; take the above American ginseng fine powder and extract powder and mix , dried, granulated, passed through a 100-mesh sieve, and packed into bags.

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PUM

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Abstract

A Chinese medicine in the form of powder for treating type-B diabetes and insulin-resistant syndrome in prepared from 12 Chinese-medicinal materials including American-ginseng, astragalus root root, haw, wolfberry fruit, etc through grinding American ginseng, extracting from others in water, depositing in alcohol, concentrating, drying, pulverizing, and mixing with the powdered American ginseng. Its advantages are high curative effect and no by-effect.

Description

technical field [0001] The invention relates to a Chinese patent medicine for treating diabetes and a preparation method thereof. Background technique [0002] Diabetes belongs to the category of diabetes in traditional Chinese medicine. At present, there are about 120 million diabetic patients in the world. It is the third largest disease after tumors and cardiovascular diseases. Most patients with non-insulin-dependent diabetes mellitus (NIDDM). [0003] The treatment of diabetes mainly adopts oral hypoglycemic drugs, such as glyburide, Damekang, etc., or insulin injection, but the subsequent failure of oral sulfonylurea hypoglycemic drugs and insulin injection resistance syndrome have become new problems. treatment difficulties. Thiazolidinedione derivatives drugs, such as rosiglitazone, pioglitazone, and troglitazone, have good hypoglycemic and blood pressure-lowering effects on type II non-insulin-dependent diabetes mellitus (NIDDM), but their side effects Large, esp...

Claims

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Application Information

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IPC IPC(8): A61K36/8968A61K36/8964A61K36/8945A61K36/815A61K36/804A61K36/57A61K36/481A61K36/48A61K36/428A61K36/40A61K36/258A61K36/54A61K9/20A61K9/48A61K9/08A61K9/10A61P3/10
Inventor 王锦刚
Owner SHAANXI KANGHUI PHARMA CO LTD
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