Medicines composition for treating diabetes and its prepn

A composition and drug technology, which is applied in the direction of drug combination, pharmaceutical formula, medical preparations containing active ingredients, etc., can solve the problems of patients with secondary drug failure, leukocyte granulocyte and thrombocytopenia, and obvious side effects

Inactive Publication Date: 2003-03-19
SHIJIAZHUANG YILING PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] Diabetes Mellitus (Type II diabetes) is clinically characterized by thirsty and polydipsia, eliminating food and hunger. At present, the medicines for treating diabetes are divided into three categories: 1. Western medicines, which are based on insulin and second-generation sulfonyl The urea drug glyburide is the representative, the advantage is that the symptoms can be controlled quickly and the effect is remarkable, but the side effects are obvious. 2. Combination of Chinese and Western medicines, such medicines are represented by "Zhongyi Xiaoke Pills" produced by Guangzhou No. 1 Traditional Chinese Medicine Factory. Hypoglycemic, the drug has the characteristics of nourishing yin and nourishing the kidney, nourishing qi and promoting body fluid, and quick curative effect, but each pill still contains 0.25mg of western medicine glyburide, so there are still damages to liver and kidney function and secondary drug effects in patients. 3. Pure Chinese medicines, such as Zuoguiyin, Liuwei Dihuang Pills, Ginseng Glycopeptide Injection

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0011] Example 1: Ginseng 83g Polygonatum 110g Atractylodes rhizome (fried) 55g Sophora flavescens 45g Ophiopogon japonicus 110g Rehmannia glutinosa 83g (burned) 67g Cornus 110g Poria 67g Perrin 45g Coptidis 45g Epimedium (burned) 45g Anemarrhena 55g Salvia 72g Pueraria 110g Litchi core 110g Digupi 67g Preparation method:

[0012] (1), take Peilan and Atractylodes atractylodes and combine distillation to extract volatile oil, the distilled aqueous solution is collected in another device, and the residue and its aqueous solution are set aside;

[0013] (2), according to the percolation method of Cornus officinalis ("Chinese Pharmacopoeia" 2000 edition an appendix 10) with 8 times the amount of 75% ethanol as solvent, after soaking for 24 hours, carry out percolation, percolation speed 3ml / min, collect percolation Liquid 700ml, recover ethanol, and concentrate into clear ointment for subsequent use;

[0014] (3) After soaking the other 14 flavors such as ginseng with 8 times th...

Embodiment 2

[0015] Example 2. Ginseng 83g Polygonatum 110g Atractylodes atractylodes (fried) 55g Sophora flavescens 45g Ophiopogon japonicus 110g Peilan 45g Anemarrhena 55g Salvia 72g Poria cocos 67g Polygonum multiflorum (burned) 67g Pueraria 110g Litchi core 110g Raw rehmannia 83g Digupi 67g

Embodiment 3

[0016] Example 3. Ginseng 42g Polygonatum 55g Atractylodes atractylodes (fried) 55g Sophora flavescens 20g Ophiopogon japonicus 55g Peilan 45g Anemarrhena 55g Salvia 36g Poria cocos 35g Polygonum multiflorum (burnt) 67g Pueraria 110g Litchi core 110g Rehmannia glutinosa 40g Digupi 30g Xianling spleen 20g

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PUM

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Abstract

The present invention provides one oral liquid for treating diabetes based on the treating principle of benefiting vital energy, nourishing Yin, invigorating spleen and activating thin fluid. The composite medicine has 14 kinds of Chinese medicinal materials including ginseng, sealwort, atractylodes rhizome, flavescent sophora root, ophiopogon root, etc. The pharmacological test shows that the medicinal oral liquid of the present invention can reduce the blood sugar level of rat of hyperglycaemia and raise the activity of SOD while producing no obvious effect on the secretion of insulin and blood fat.

Description

technical field [0001] The invention relates to a pharmaceutical composition for treating diabetes (diabetes) and a preparation method, which belongs to the technical field of Chinese herbal medicine preparations, and is especially suitable for clinically treating type II diabetes with thirst, polydipsia, gluten and hunger, excessive urination, emaciation, and burnout Fatigue and other symptoms. Background technique [0002] Diabetes Mellitus (Type II diabetes) is clinically characterized by thirsty and polydipsia, eliminating food and hunger. At present, the medicines for treating diabetes are divided into three categories: 1. Western medicines, which are based on insulin and second-generation sulfonyl The urea drug glyburide is the representative, the advantage is that the symptoms can be controlled quickly and the effect is remarkable, but the side effects are obvious. 2. Combination of Chinese and Western medicines, such medicines are represented by "Zhongyi Xiaoke Pill...

Claims

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Application Information

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IPC IPC(8): A61P3/10
Inventor 吴以岭
Owner SHIJIAZHUANG YILING PHARMA
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