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Composition containing plant estrogen and amino glucose against bone retrograde affection and preparation

A technology of phytoestrogens and glucosamine, which is applied in the field of compositions and preparations containing phytoestrogens and glucosamine, which can solve the problems of weak and slow action in relieving bone and joint pain, achieve bone and joint pain relief, and improve metabolism problems, improve the effect of osteoporosis

Inactive Publication Date: 2004-07-07
孙家莉
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, phytoestrogens and soybean isoflavones alone are used to improve osteoporosis. However, middle-aged and elderly people have bone degeneration, bone and cartilage degenerative changes, and osteoporosis is always accompanied by bone and joint pain. Therefore, However, the single use of phytoestrogens and soybean isoflavones to improve osteoporosis not only slows down the effect, but also has little effect on relieving bone and joint pain.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0017] Embodiment 1: A composition containing phytoestrogens and glucosamine for preventing and treating bone degeneration, characterized in that the formula and proportion of the composition are: 30% phytoestrogens and 70% glucosamine.

[0018] The above-mentioned composition can add 30% calcium-containing compound. The calcium-containing compound may be calcium lactate.

[0019] The phytoestrogens mentioned above are obtained from soybean isoflavones.

[0020] The said phytoestrogen active ingredient content should be 40%.

[0021] Above-mentioned glucosamine gets glucosamine hydrochloride, and its content is 99%.

[0022] An appropriate amount of conventional auxiliary materials can be added in the above-mentioned composition, and the auxiliary materials are talcum powder and 80% ethanol.

[0023] The dosage form mentioned above can be made into capsules.

[0024] A method for preparing a composition containing phytoestrogens and glucosamine for preventing and treating ...

Embodiment 2

[0033] Embodiment 2: with the formula proportioning of embodiment 1, the product is made into tablet, and above-mentioned said conventional process of tablet comprises pulverization, 100 order sieves, mixes evenly, adds 8% starch paste and makes soft material, 18 Sieve through mesh to make granules, dry at 60°C, granulate, add magnesium stearate, mix well, press into tablets, and then bottle the finished product.

[0034] The product is made into tablets with the ingredient ratio of

[0035] Glucosamine HCl 70% of the composition

[0036] Soy Isoflavones 30% of the composition

[0037] 30% of calcium gluconate products

[0038] 8% starch paste appropriate amount

[0039] Magnesium Stearate Appropriate amount

[0040] As a tablet 400 capsules

[0041] Dosage form stability test of the present invention: under the condition of temperature 20-30 ℃ of relative humidity 40-80%, to the capsule that embodiment 1 makes, be contained in the pl...

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Abstract

A composite medicine for preventing and treating the retrograde bone lesion, osteoporosis and osteoarthrodynia contains vegetable estrogen (30-50%) and aminoglocose (50-70%), and is prepared through extracting the vegetable estrogen from relative plant, preparing the aminoglocose hydrochloride (or sulfate) from the the shell of shrimp and crab or the chitin, and conventionally preparing said medicine. Its advantages are high curative effect and no toxic by-effect.

Description

(1) Technical field: [0001] The invention relates to a medicine, a health care product and a preparation method capable of preventing and treating senile bone degeneration, in particular to a composition containing phytoestrogens and glucosamine for preventing and treating bone degeneration and a preparation method. (two) background technology: [0002] After menopause, the level of estrogen in women decreases, which affects the formation of calcium-regulating hormones, parathyroid hormone, calcitonin and VD, directly and indirectly unbalances bone metabolism, increases bone resorption, decreases bone formation, and decreases bone density, resulting in Osteoporosis, patients with low back pain, spinal compression, short stature, and hunchback; at the same time, articular cartilage synthesis protein decreases, cartilage matrix proteoglycan content decreases, proteoglycan ability to aggregate into macromolecules decreases, loss increases, and cartilage appears Degeneration, de...

Claims

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Application Information

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IPC IPC(8): A61K31/7008A61K31/7048A61P19/02A61P19/10A61P29/00
Inventor 孙家莉
Owner 孙家莉
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