Infant formula supplemented with phospholipids

A technology for food and baby, applied in the field of baby food supplemented with phosphatidylserine, can solve the problem that phosphatidylserine cannot be used in baby food, etc., and achieve the effects of increasing protection, enhancing development and maturation

Inactive Publication Date: 2004-08-25
LIPOGEN
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, at present, this source of phosphatidylserine cannot be used in baby food due to "mad cow disease"

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1-1

[0028] Tables 1 and 2 below provide exemplary components of powdered and fluid milk-based, and dry and fluid soy-based infant food products according to the present invention.

[0029] Baby food I (milk based)

[0030] This baby food contains the following ingredients: lactose, vegetable oil, skimmed milk powder, whey protein concentrate, sodium, calcium, phosphorus, potassium, chloride, iron, magnesium, taurine, vitamins, and phospholipids.

[0031] Table I

[0032] Common components unit powder 100g fluid 100ml

[0033] Protein grams 11.1 1.5

[0034] Fat grams 25.9 3.5

[0035] Lactose g 55.5 7.5

[0036] Water g 2.5 ---

[0037] Ash content g 2.06 0.27

[0038] vitamins

[0039] Vitamin A I.U. 1500 200

[0040] Vitamin D I.U. 300 40

[0041] Vitamin E mg 6 0.81

[0042] Vitamin K μg 15 2.01

[0043] Vitamin B1 μg 350 47.03

[0044] Vitamin B2 μg 450 60

[0045] Vitamin B6 μg 222 30

[0046] Vitamin B12 μg 0.66 0.09

[0047] Niacin m...

Embodiment 2-1

[0172] Soybean lecithin (50 g; product name Epikuron 135; Lucas Meyer GmbH, Germany) and soybean oil (10 g) were charged into a 300-ml vial, and ethyl acetate (50 ml) was added for dissolution. To the resulting solution was added a 0.30 g / ml L-serine solution (20 ml) dissolved in 0.1 M sodium phosphate buffer, pH 7.0, and mixed thoroughly. 500 U / ml of phospholipase-D solution from cabbage was added to the mixed solution, and reacted at 25°C for 5 hours under the agitation of a stirrer.

[0173] To inactivate the enzyme in the reaction solution, the vial containing the reaction solution was immersed in hot water. Subsequently, the reaction solution was cooled on ice and treated with chloroform. The chloroform layer was collected under reduced pressure and dried.

Embodiment 2-2

[0175] Using egg yolk lecithin (product name DS-PL95E; produced by Doosan Corp. Venture BG Biotech BU., Korea) as a substrate, rearranged phosphatidylserine was produced in the same manner as in Example 1-1.

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PUM

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Abstract

The present invention relates to pharmaceutical or nutritional or food compostion for feeding infants, which is more similar to human milk in a powder or fluid form, having an effect of addresseing the shortcomings of the presently known infant formulas by the inclusion of a phospholipid supplement which contains phosphatidylserine or salts thereof as one of the effective ingredients and comprising at least 1% (w / w) phosphatidyserine out of the total phospholipid content of the composition, wherein the phosphatidylserine has a structural fatty acid chain derived from at least one raw material lecithin selected from the group consisting of soy bean lecithin, rapeseed lecithin, or egg yolk lecithin, and which is produced by reaction with phospholipase-D.

Description

technical field [0001] The present invention relates to a baby food added with glycerophosphate (hereinafter referred to as phospholipid), more particularly, to a baby food added with phosphatidylserine. Background technique [0002] Breastfeeding, the natural form of breastfeeding, has several beneficial effects on infants and is known to be the best diet for infants' nutritional needs. [0003] Jensen RG. (Texbook of Gastroenterology and Nutrition in Infancy, Second Edition, edited by E. Lebenthal, Raven Publishing Ltd., pp. 157-208, New York, 1989) reviews Measurement of total lipid content in human milk and reports that phospholipids are found at levels of about 20 to 40 mg / dl in human milk. [0004] G.Harzer et al. reported that the phospholipid composition (weight % of total phospholipids) of postpartum 36 days human milk lipid was, phosphatidylcholine (PC) 24.9%, phosphatidylethanolamine (PE) 27.7%, phosphatidylserine (PS ) 9.3%, phosphatidylinositol (PI) 5.4%, sphi...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A23C11/02A23C9/152A23J7/00A23L1/30A23L33/00A61K31/685A61P25/00
CPCA23V2002/00A23L1/296A23J7/00A23L33/40A61P25/00A23V2250/1844A23V2250/1852A23V2250/1846A23V2250/1848A23V2250/185
Inventor 大卫·鲁滕贝格
Owner LIPOGEN
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