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Chinese patent drug for treating heart brain blood vessel disease and its preparation method

A technology for cardiovascular and cerebrovascular diseases and Chinese patent medicines, which can be used in the field of medicine to solve problems such as insufficient research

Active Publication Date: 2005-03-23
SHANXI SHUANGREN PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Modern research shows that kudzu root and hawthorn have obvious effects of expanding the crown, reducing myocardial oxygen consumption, anti-myocardial ischemia, anti-myocardial injury, anti-oxidation, scavenging free radicals, anti-platelet aggregation, lowering blood lipids, lowering blood pressure, and anti-arrhythmia and other effects, the main active ingredients of hawthorn total flavonoids and puerarin contained in it have significant therapeutic effects on coronary heart disease, angina pectoris, hypertension and other diseases. However, the research on its specific dosage and its preparation process has not been in-depth. The processing of raw materials is made by water extraction. It is a necessary process to improve the clinical effect of Xinxuening, and it is also the general trend of the development of traditional Chinese medicine to further increase the content of its active ingredients.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0276] (1) Put pueraria root powder in a percolation tank, add ethanol for cold soaking for three days, release the soaking liquid, add another soaking in ethanol for two days the next day, combine two soaking liquids; or heat reflux, extract three times with ethanol each time 5-25 times the amount, filter; combine the three filtrates, recover ethanol, concentrate to a thick paste, add starch, and dry at 80°C to obtain it;

[0277] (2) Put the hawthorn in a sandwich pot, add cold water, decoct twice, boil for the first time for 1 hour and combine the two filtrates, the film is concentrated to half, move it to an open pot, add concentrated hydrochloric acid (industrial) to adjust the pH to about 1. Remove the supernatant, take out the precipitate and dry it, wash it with water until there is no obvious acidity; or use ethanol as a solvent, the amount of solvent is 5-25 times, heat extraction three times, and filter; combine the three filtrates, recover ethanol, and make dry pas...

Embodiment 2

[0280] The extracting method of Radix Puerariae Hawthorn is the same as Example 1;

[0281] Take 80-190 parts by weight of kudzu root alcohol extract, 30-120 parts by weight of hawthorn water or alcohol extract, add appropriate amount of auxiliary materials starch and PVP, ultrafinely pulverize, use ethanol as a binder to make granules and pack them into capsules, and make heart-blood Ning capsules;

Embodiment 3

[0283] The extracting method of Radix Puerariae Hawthorn is the same as Example 1;

[0284] Take 100-190 parts by weight of kudzu root alcohol extract, 30-80 parts by weight of hawthorn water or alcohol extract, add auxiliary materials such as starch, ultrafinely pulverize, use ethanol as a binder to make granules, press into tablets, coat, and prepare Xinxuanning Tablets,

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Abstract

A Chinese patent drug for treating cardiovascular and cerebrovascular diseases, such as coronary heart disease, angina pectoris and hypertension, is prepared from pueraria root and haw. Its preparing process is also disclosed.

Description

Technical field: [0001] The invention belongs to the field of medicine, relates to a Chinese patent medicine for treating cardiovascular and cerebrovascular diseases, and is a new Xinxuening preparation. Background technique: [0002] Coronary heart disease, angina pectoris, hypertension, etc. are common diseases of middle-aged and elderly people, and they are also one of the main diseases that endanger human health. With the improvement of living standards, the acceleration of the pace of life, and the increasingly fierce social competition, people's cerebral cortex is in a state of high tension, and their mental pressure is increasing day by day. High accounted for the first of various diseases. With the continuous development of medicine, great progress has been made in the treatment of cardiovascular and cerebrovascular diseases by drugs. However, for the toxic and side effects and adverse reactions in the treatment of western medicine, the treatment of cardiovascular a...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/08A61K9/10A61K9/16A61K9/20A61K9/48A61K9/50A61P9/10A61P9/12
Inventor 冯德芹
Owner SHANXI SHUANGREN PHARMA
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