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A method for preparing sustained-release micro-pellet feeding enzyme

The invention relates to a technology of slow-release pellet enzyme and feed enzyme, which is applied to feed slow-release pellet enzyme and slow-release pellet. It can solve the problems of reduced particle solubility, reduced bioavailability of particle components, and complex process

Inactive Publication Date: 2006-11-22
珠海天翼医药技术开发有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

This method is complicated in process, and it is coated with fat or wax. Due to the hydrophobicity of the coating, the solubility of the coated particles is reduced.
It has been found that due to these special coatings, the bioavailability of the granule components is reduced

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0019] Contain in every 1000g pellet enzyme of embodiment 1:

[0020] Powdered Compound Enzyme 800g

[0021] Hydroxypropyl Methyl Cellulose 10g

[0022] Xanthan gum 20g

[0023] Polyethylene glycol 10g

[0024] Ethyl cellulose 60g

[0025] Talc powder 10g

[0026] Calcium carbonate 90g

[0027] Preparation of adhesive: Accurately weigh hydroxypropyl methylcellulose, prepare a solution with water, and set aside.

[0028] Preparation of enzyme-containing pellets: mixing enzyme talc powder with calcium carbonate, spraying adhesive while coating powder in a coating pan to form enzyme-containing pellets, and drying.

[0029] Preparation of coating liquid: ethyl cellulose xanthan gum and polyethylene glycol are prepared into water dispersion and set aside.

[0030] Take the above drug-containing pellets and put them in the coating pot, the pot speed is 10-20 rpm, the temperature in the pot is 20-40°C, continuously spray the coating solution on the enzyme-containing pellets, a...

Embodiment 2

[0031] Embodiment 2: the controlled-release controlled-release pellet of every 1000g phytase contains:

[0032] Phytase 200g

[0033] Acrylic resin 200g

[0034] Polyethylene glycol 20g

[0035] Sodium Alginate 150g

[0036] Talc powder 10g

[0037] Starch 380g

[0038] Microcrystalline Cellulose 200g

[0039] Preparation of adhesive: Accurately weigh hydroxypropyl methylcellulose, prepare a solution with water, and set aside.

[0040] Preparation of enzyme-containing pellets: mixing enzyme sodium alginate talcum powder starch and microcrystalline cellulose, spraying adhesive while powdering in a coating pan to form enzyme-containing pellets, and drying.

[0041] Preparation of coating liquid: acrylic resin and polyethylene glycol are prepared into water dispersion, and set aside.

[0042] Take the above-mentioned enzyme-containing pellets and put them in the coating pot, the rotation speed of the pot is 10-20 rpm, the temperature in the pot is 20-40°C, continuously spr...

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Abstract

The present invention relates to one kind of slow released enzyme micro pill for feed and its preparation process. The slow released enzyme micro pill is prepared through a rolling process, is stable during further feed production, and has its enzyme released slowly or in certain location to produce lasting effect. The present invention is superior to common enzyme preparation, which is instable in the intracorporeal environment.

Description

Technical field: [0001] The invention relates to a sustained-release pellet enzyme for feed, which belongs to the field of feed additives and is a slow-release pellet made of one or more feed enzymes. Background technique: [0002] Enzyme preparation is a new type of high-efficiency feed additive. In the early 1990s, my country began the research and application of feed enzyme preparation, and gradually applied it to various breeding fields such as livestock, poultry, and aquatic animals. Feed enzymes can not only promote the digestion and absorption of nutrients by animals, improve the utilization rate of feed, promote animal growth, improve the production performance of livestock and poultry, but also prevent the occurrence of certain diseases, and are non-toxic, have no side effects, and have no residues. [0003] During feed processing, heat treatment and extrusion are required, such as being heated and moistened by steam. Both of these processes destroy the enzymes pre...

Claims

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Application Information

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IPC IPC(8): A23K20/189A23K40/30A61K9/22
Inventor 张晓明
Owner 珠海天翼医药技术开发有限公司
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