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Medication composition of replenishing qi to invigorate the spleen, preparation method and usage

A technology for nourishing qi and strengthening the spleen and a composition is applied in the field of pharmaceutical compositions for nourishing qi and strengthening the spleen, and can solve the problems of easy loss of active ingredients, unclear drug effect, and easy volatilization of volatile oil, and achieve clear and controllable drug effect. Strong, stable quality effect

Inactive Publication Date: 2006-12-06
CHENGDU UNIV OF TRADITIONAL CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Due to the simple process, the volatile oil is easy to volatilize, and the active ingredients are easy to lose, so the efficacy is not clear

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0026] The extraction process of embodiment 1 raw material of the present invention

[0027] Take the red ginseng medicinal material, add 50% ethanol to soak, reflux extraction, filter, and combine the filtrate; the medicinal liquid recovers ethanol, concentrates, and puts on a macroporous adsorption resin, first uses 20% ethanol to elute and remove impurities, and then uses 70% ethanol For elution, collect the 70% ethanol eluate, recover the ethanol, concentrate, and set aside. Atractylodes macrocephala soaked in solvent oil (or vegetable oil), reflux extraction, filtration, the filtrate recovered solvent, added to β-cyclodextrin aqueous solution, ultrasonic inclusion, refrigeration, centrifugation, precipitation for later use; take Atractylodes macrocephala residue, add ethanol to extract and filter After drying, the medicinal residues are mixed with red ginseng medicinal residues, decocted with water, filtered, the filtrate is concentrated, centrifuged, and the supernatant ...

Embodiment 2

[0028] The extraction process of embodiment 2 raw materials of the present invention

[0029] Take the red ginseng medicinal material, add 80% ethanol to soak, reflux extraction, filter, and combine the filtrate; the medicinal liquid recovers ethanol, concentrates, and puts on a macroporous adsorption resin, first uses 20% ethanol to elute and remove impurities, and then uses 70% ethanol For elution, collect the 70% ethanol eluate, recover the ethanol, concentrate, and set aside. Soak Atractylodes macrocephala in solvent oil (or vegetable oil), reflux extraction, filter, recover the solvent from the filtrate, concentrate, and set aside; take Atractylodes macrocephala, add ethanol to extract and filter, mix the drug residue with red ginseng, add water to decoct, and filter , the filtrate was concentrated, centrifuged, and the supernatant was alcohol-precipitated, centrifuged, and precipitated for later use. The red ginseng saponin concentrate is added with Atractylodes macroce...

Embodiment 3

[0030] Embodiment 3 preparation of medicine of the present invention

[0031] According to the method of Example 1, 50 g of total ginsenosides, 10 g of Atractylodes macrocephala volatile oil, 50 g of red ginseng and Atractylodes macrocephala complex polysaccharides were prepared, starch was added to granulate and granulate, magnesium stearate was added, and tablets were compressed to obtain tablets.

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PUM

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Abstract

A composite medicine for treating the precanerous lesion of stomach cancer is prepared from general ginsenoside, the oil and polyose of white atractylodes, and red ginseng. Its preparing process and usage are also disclosed.

Description

technical field [0001] The invention relates to a pharmaceutical composition for invigorating qi and invigorating the spleen, in particular, it is a pharmaceutical composition prepared from effective parts extracted and prepared from Chinese medicinal materials as raw materials, and belongs to the field of pharmaceuticals. Background technique [0002] It is well known that malignant tumors pose a serious threat to human physical and mental health. 35% of the patients who die from malignant tumors all over the world are tumors of the digestive system, among which the death rate of gastric cancer ranks first. In 1997, the cancer situation in my country was announced, and the mortality rate of cancer had risen from 11.7% in the 1970s to 18.14% in the 1990s, and gastric cancer ranked first among the 10 malignant tumors. Studies in recent years have shown that before gastric cancer develops from normal tissues to malignant tumors, it has to go through a rather long evolution st...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/258A61P1/14A61P35/00
Inventor 彭成郭力张磊夏厚林万丽曹小玉
Owner CHENGDU UNIV OF TRADITIONAL CHINESE MEDICINE