Soft capsule of atovastatine salts and prepn. method therefor

A technology of atorvastatin and soft capsule, applied in the field of medicine, can solve the problems of instability, stability and reduction, and achieve the effects of easy storage and storage, high bioavailability and rapid dissolution
CN1911213AActive Publication Date: 2007-02-14CSPC OUYI PHARM CO LTD
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
CSPC OUYI PHARM CO LTD
Publication Date
2007-02-14
Patent Text Reader

Abstract

A soft capsule of lipitor salt with high stability and disintegrating speed is prepared from lipitor salt, auxiliary, and soft shell prepared from gelatin, glycerin, distilled water, ethylparaben, Fe2O3, microcrystalline cellulose and antioxidant. Its preparing process is also disclosed.
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Description

technical field

[0001] The invention relates to a pharmaceutical preparation and a preparation method, in particular to an atorvastatin salt soft capsule and a preparation method thereof, belonging to the technical field of medicine. Background technique

[0002] Atorvastatin (Atorvastatin Calcium) is a selective and competitive inhibitor of 3-hydroxy-3-methyl-glutaryl coenzyme A (HMG-CoA) reductase, which is a rate-limiting An enzyme that converts 3-hydroxy-3-methyl-glutaryl-CoA to mevalonate (a precursor of sterols including cholesterol). Triglycerides and cholesterol are combined in the liver to form very low-density lipoprotein cholesterol (VLDL) and released into the plasma for further transport to surrounding tissues. Low-density lipoprotein cholesterol (LDL) is formed from very low-density lipoprotein cholesterol (VLDL) and is catabolized primarily by high-affinity low-density lipoprotein cholesterol (LDL) receptors.

[0003] Atorvastatin reduces plasma cholesterol ...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
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