Composite implant having porous structure filled with biodegradable alloy and method of magnesium-based manufacturing the same

a biodegradable alloy and composite implant technology, applied in dental surgery, prosthesis, impression caps, etc., can solve the problems of easy damage, easy to be damaged, difficult to manufacture, etc., to accelerate the formation of bone, prevent the effect of stress shielding phenomenon, and increase the bone formation ra

Inactive Publication Date: 2011-03-03
U & I INC
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Benefits of technology

[0011]According to the biodegradable composite implant of the present invention, bone formation rate is increased by the formation of blood vessels through pores. Specifically, when the biodegradable composite implant according to the present invention was introduced into the human body, a magnesium-based alloy filled in the inner pores decomposes as time passes, and the pores of the porous structure become vacant, so that blood vessels are formed through the vacant pores of the porous structure, thereby accelerating the formation of bone.
[0012]Further, according to the biodegradable composite implant of the present invention, a stress shielding phenomenon is prevented due to the decrease of Young's modulus. Specifically, the inner parts of pores are filled with magnesium (Mg) having a low Young's modulus, so that the Young's modulus of the biodegradable composite implant according to the present invention also becomes low, thereby preventing the stress shielding phenomenon.
[0013]Further, according to the biodegradable composite implant of the pr...

Problems solved by technology

Among them, metallic implants have excellent mechanical properties and workability, but have disadvantages such as stress shielding, image degradation, implant migration and the like.
Further, ceramic implants have relatively excellent biocompatibility, but are disadvantageous in that they are easily damaged by external impacts and are difficult to manufacture.
Further, polymeric implants are disadvantageous in that they have relatively low strength compared to other implant materials.
However, these porous implants are disadvantageous in that they are vulnerable to external impacts due to their low mechanical strengths.
However, such biodegradable polymers are problematic in that they have low mechanical stren...

Method used

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  • Composite implant having porous structure filled with biodegradable alloy and method of magnesium-based manufacturing the same
  • Composite implant having porous structure filled with biodegradable alloy and method of magnesium-based manufacturing the same
  • Composite implant having porous structure filled with biodegradable alloy and method of magnesium-based manufacturing the same

Examples

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Effect test

example 1

Manufacture of an Alumina Implant Filled with Magnesium

[0068]200 mL of ethanol, as a solvent, 6 g of polyvinyl butyral-co-vinyl alcohol-co-vinyl acetate (PVB), as a binder, 6 mL of triethyl phosphate (99.8%), as a dispersant, and 50 g of alumina, as a biodegradable ceramic, were mixed and then stirred for 2 hours to form a mixed solution. Subsequently, zirconia balls were put into the mixed solution and ball-milling was performed for about 24 hours. Then, polyurethane cut in a predetermined size and shape was immersed into the mixed solution, taken out, and then rotated at room temperature to prevent the pores from clogging by the solution. Subsequently, the polyurethane was dried in the air for about 5 minutes to cause the polyurethane foam material to be covered with highly-concentrated alumina. As described above, the process of immersing the polyurethane into the mixed solution and then drying the polyurethane was repeatedly conducted, thus forming an alumina mixed film having a...

example 2

Manufacture of a Titanium Implant Filled with Magnesium

[0071]The titanium porous structure was prepared by a rotating electrode method in which spherical titanium (Ti) powder having a diameter of 100˜200 μm was interposed between conductive electrodes and then an voltage which is charged in a 450 μF capacitor on condition of 1.0 kJ or 1.5 kJ is instantaneously discharged using a high-vacuum switch while current and voltage passing through the powder during the electric discharge are controlled, thus executing rapid sintering of the spherical titanium (Ti) powder.

[0072]A copper electrode bar was provided under a quartz tube having an inner diameter of 4.0 mm, and 0.7 g of sorted titanium powder was introduced into the quartz tube, and then the titanium powders were sufficiently packed each other using a vibrator. Meanwhile, 10 kg of a load was applied to the upper copper electrode bar using an automatic loading apparatus to connect the copper electrode to the upper part of titanium p...

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Abstract

The present invention provides a composite implant comprising pores of a porous structure filled with a biodegradable magnesium-based alloy. Further, the present invention provides a composite implant which filles pores of the porous structure prepared by a metal, a ceramic or a polymer with a biodegradable magnesium-based alloy. Mechanical properties of the composite implant of the present invention are improved because a magnesium-based alloy filled in its pores increases the strength of a porous structure comprised of a metal, a ceramic or a polymer. Further, it can be expected that the magnesium-based alloy filled in the porous structure is decomposed in a living body, thus increasing bone formation rate. Accordingly bone tissue can be rapidly formed because the composite implant of the present invention has high strength and excellent interfacial force between the composite implant and bone tissue, compared to conventional porous materials.

Description

TECHNICAL FIELD[0001]The present invention relates to a composite implant having a porous structure filled with a biodegradable alloy and a method of manufacturing the same. More specifically, the present invention relates to a composite implant having a porous structure filled with magnesium or magnesium-based alloy which is biodegradable and thus has a controllable biodegradation rate, which has high strength and excellent interfacial force between the magnesium or magnesium-based alloy and bone tissue and which can improve a bone formation rate, and a method of manufacturing the same.BACKGROUND ART[0002]Typical materials of implants used for medical treatment include metals, ceramics, polymerics and the like. Among them, metallic implants have excellent mechanical properties and workability, but have disadvantages such as stress shielding, image degradation, implant migration and the like. Further, ceramic implants have relatively excellent biocompatibility, but are disadvantageo...

Claims

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Application Information

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IPC IPC(8): A61F2/28B05D7/00B05D3/02
CPCA61L27/427A61L27/58A61L27/446A61F2/28A61C8/00
Inventor SEOK, HYUN-KWANGYANG, SEOK-JOKIM, YU-CHANKOO, JA-KYO
Owner U & I INC
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