Long-acting polypeptides and methods of producing and administering same

a polypeptide, long-acting technology, applied in the direction of growth factors/regulators, animal/human proteins, anti-mimetic/scaffolds, etc., can solve the problems of preventing the development of many otherwise promising drug candidates, affecting the development of drug candidates, and affecting the effect of the area under the curv
US20150038413A1Pending Publication Date: 2015-02-05OPKO BIOLOGICS
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Patent Information

Authority / Receiving Office
US · United States
Current Assignee / Owner
OPKO BIOLOGICS
Publication Date
2015-02-05

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Abstract

A polypeptide and polynucleotides comprising at least two carboxy-terminal peptides (CTP) of chorionic gonadotrophin attached to a non-human peptide-of-interest are disclosed. Pharmaceutical compositions comprising the non-human polypeptides and polynucleotides of the invention and methods of using both human and non-human polypeptides and polynucleotides are also disclosed.
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Description

CROSS REFERENCE TO RELATED APPLICATIONS

[0001] This application is a continuation in part of U.S. patent application Ser. No. 14 / 059,134, filed Oct. 21, 2013, which is a continuation in part of U.S. patent application Ser. No. 13 / 804,354 filed Mar. 14, 2013, which is a continuation in part of U.S. patent application Ser. No. 13 / 192,542 filed Jul. 28, 2011, which is a continuation of U.S. patent application Ser. No. 12 / 401,755 filed Mar. 11, 2009, which is a continuation of U.S. application Ser. No. 11 / 702,156 filed on Feb. 5, 2007, now abandoned, which claims the benefit of U.S. Provisional Application Ser. No. 60 / 764,761, filed Feb. 3, 2006. This application is also a continuation-in-part of U.S. patent application Ser. No. 13 / 195,931, filed Aug. 2, 2011, which is a continuation-in-part of U.S. patent application Ser. No. 12 / 509,188, filed Jul. 24, 2009, which is a continuation-in-part of U.S. patent application Ser. No. 12 / 476,916, filed Jun. 2, 2009, which is a continuation-in-part...

Claims

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