The invention discloses a method for interacting signaling safely in a session ignition protocol (SIP) registration domain. The registration authentication process is the challenge-based registration authentication process which is defined in the RFC3261, but a digital certificate of the double-key mechanism is adopted in the registration authentication process, therefore, the bidirectional digital-certificate based authentication mechanism is realized, and a shared key SEED used for the non-registration signaling digital abstract authentication is transmitted safely. The non-registration authentication signaling adopts a convenient and efficient digital abstract authentication mode with strong compatibility so that the secure computing expenditure is very little, and the coexistence of high safety and high performance is realized. The invention can prevent the Impersonation attack, the Bye attack, the Cancel attack, the REFER attack, the UPDATE attack and other typical SIP attacks of the server. The invention utilizes the association of the registration authentication and the non-registration authentication and combines the high safety of the double-key authentication and the high efficiency of the digital abstract authentication, thereby having high utility value.