Plumepoppy total alkaloid salt and its prepn and application

Abstract

The present invention is new total plumepoppy alkaloid salt and its preparation and application. The total plumepoppy alkaloid salts of organic acid and boric acid have the content of 50-90 % accounting in the organic acid salt and boric acid salt of sanguinarine and chelirubine. The total plumepoppy alkaloid salts of organic acid and boric acid have the antibacterial and antiphlogistic activity superior to that of total plumepoppy alkaloid sulfate and hydrochloride. The present invention also relates to the antibacterial and antiphlogistic application of medicines and daily use articles containing total plumepoppy alkaloid salts of organic acid and boric acid for human and animal.

Description

technical field [0001] The present invention relates to new Boluohui total alkaloid organic acid salt and borate and its application and preparation method. Background technique [0002] Bo Luohui (Macleaya cordata (Willd.) R.Br.), also known as trumpet grass, trumpet pole, paulownia pole, Bolehui, Shandatong, yellow mint, yellow woman, three money three, wild pockmark, blowing torch, It is a perennial tall herb of poppy Keboluohui. It has a long history in my country to use Boluohui to treat scabies, furunculosis and kill insects and maggots. The earliest Materia Medica literature that records Bo Luohui is "Materia Medica Supplements". It is now uniformly named as Boluohui, and it is widely used as raw material for medicine, biopesticide, veterinary medicine, and fine chemical products. [0003] Boluohui is a tall perennial herb, 1-2.5m high, with white powder all over, and yellow juice flows out after breaking. Root thick, orange red. Stem cylindrical, erect, hollow, gr...

AI Technical Summary

Problems solved by technology

[0011] Although Boluohui alkaloid has obvious biological activity, its solubility is very low, and it is easy to change under alkaline conditions. Therefore, it is difficult for Boluohui alkaloid to directly exert its many biological activities, so it appears Most of the products are used in products with their hydrochloride or sulfate

However, whether it is reasonable to use the hydrochloride or sulfate of the total alkaloids of cypress to replace the total alkaloids of cypress, whether it can improve or guarantee the biological activity of the total alkaloids of cypress, has not been discussed in the existing relevant cypress It has been reported in the application and research literature, and the lack of effective research and demonstration is a problem that needs to be further explored.