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Chinese medicinal herb oral administration particle for treating oxyhepatitis

A technology of acute hepatitis and Chinese herbal medicine, which is applied in the field of Chinese patent medicine compounding, can solve the problems of cumbersome production process, drug safety problems, and high cost of medicines, and achieve low cost, no drug residues and side effects, and low cost.

Inactive Publication Date: 2010-09-01
HAINAN NORMAL UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, there are many preparations for treating hepatitis, but they generally have a single effect. Some preparations have too many types of Chinese herbal medicines, the production process is very cumbersome, and the resources are seriously insufficient, and the cost of forming the medicine is too high; security issues

Method used

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Examples

Experimental program
Comparison scheme
Effect test

example 1

[0011] Example 1: Take 7 kinds of Chinese herbal medicines, including 25 grams of Desmodium, 15 grams of Tianjihuang, 15 grams of bamboo leaves, 25 grams of Imperata rhizome, 30 grams of Goosegrass, 10 grams of plantain core and 30 grams of Hexagonal, and grind and sieve them respectively. Mix, add 6 times of distilled water (w / v), boil and simmer for 90 minutes, filter and add 2 times of boiling distilled water, boil and simmer for about 40 minutes, then filter, combine the filtrate, concentrate the filtrate to 120 ml with a rotary evaporator, add The starch is made into agglomerates and sieved into strips, dried at 50°C and sieved again to make granular preparations.

[0012] Preparation efficacy test: Kunming mice were divided into 3 groups: blank control group, model control group, and drug group, and injected with 2% CCL 4 Oil solution and thiosulfamide (TAA) were used to prepare the acute chemical liver injury model in mice, and the concentration of 1 gram of crude drug / ...

example 2

[0013] Example 2: Take 7 kinds of Chinese herbal medicines including 25 grams of Desmodium, 25 grams of Tianjihuang, 20 grams of bamboo leaves, 30 grams of Imperata rhizome, 40 grams of Goosegrass, 18 grams of plantain core and 35 grams of hexagonal root, and grind and sieve them respectively. Mix, add 7 times of distilled water (w / v), boil and simmer for 120 minutes, filter and add 3 times of boiling distilled water, boil and simmer for about 80 minutes, then filter, combine the filtrate, concentrate the filtrate to 150 ml with a rotary evaporator, add The starch is made into agglomerates and sieved into strips, dried at 60°C and sieved again to make granular preparations.

[0014] Preparation curative effect test: Kunming mice were divided into three groups: blank control group, model control group and drug group, and 5×10 Bacillus Calmette-Guerin (BCG) was given to the mice iv. 6 Bacteria / mouse, after 11 days, iv lipopolysaccharide (LPS) 7.5 μg / mouse, to prepare the immune ...

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PUM

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Abstract

The invention discloses a Chinese herbal medical oral granule for treating acute hepatitis, which is characterized in that the invention has the material components in weight ratio as follows: Christina Loosestrife 20 to 35, Lesser Hypericum 15 to 30, bamboo leaf 15 to 30, cogongrass 15 to 35, goose grass 25 to 50, banana stem 10 to 15 and herb of creeper rostellularia 25 to 40. The making methodis that the Christina Loosestrife, Lesser Hypericum, bamboo leaf, cogongrass, goose grass, banana stem and herb of creeper rostellularia are respectively ground in weight ratio, sifted, mixed, boiledwith distilled water and decocted in mild fire; after filtering, the distilled water is added into the filter residue, boiled, decocted in mild fire and filtered; the filtrates are merged, then the merged filtrate is concentrated; the starch is added into the filtrate to make a mass, which is filtered to be a plurality of strips, dried and filtered again to be the granules. The Chinese herbal medical oral granule has the advantages of abundant material source, low cost, safety and reliability, good efficacy, simple manufacturing technology, no drug residue, no poison and side effect, simple composition, easily available raw material, low cost and short course, which is a new drug for treating acute hepatitis.

Description

technical field [0001] The invention relates to a Chinese patent medicine compound, in particular to a Chinese herbal medicine oral granule for treating acute hepatitis. Background technique [0002] Hepatitis is a common disease, widely prevalent in all countries in the world, mainly affecting children and young adults, a small number of patients can be transformed into liver cirrhosis or liver cancer, clinical manifestations are fatigue, loss of appetite, nausea, vomiting, oily, diarrhea and abdominal distension, Some cases have fever and jaundice, and about half of the patients have insidious onset and can only be found during examination. At present, there are many preparations for treating hepatitis, but they generally have a single effect. Some preparations have too many types of Chinese herbal medicines, the production process is very cumbersome, and the resources are seriously insufficient, and the cost of forming the medicine is too high; security issues. Content...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/899A61K9/16A61P1/16A61P31/14
Inventor 陈忠陈光英龙育儒张述才舒火明韩长日
Owner HAINAN NORMAL UNIV
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