Chinese medicinal herb oral administration particle for treating oxyhepatitis
A technology of acute hepatitis and Chinese herbal medicine, which is applied in the field of Chinese patent medicine compounding, can solve the problems of cumbersome production process, drug safety problems, and high cost of medicines, and achieve low cost, no drug residues and side effects, and low cost.
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example 1
[0011] Example 1: Take 7 kinds of Chinese herbal medicines, including 25 grams of Desmodium, 15 grams of Tianjihuang, 15 grams of bamboo leaves, 25 grams of Imperata rhizome, 30 grams of Goosegrass, 10 grams of plantain core and 30 grams of Hexagonal, and grind and sieve them respectively. Mix, add 6 times of distilled water (w / v), boil and simmer for 90 minutes, filter and add 2 times of boiling distilled water, boil and simmer for about 40 minutes, then filter, combine the filtrate, concentrate the filtrate to 120 ml with a rotary evaporator, add The starch is made into agglomerates and sieved into strips, dried at 50°C and sieved again to make granular preparations.
[0012] Preparation efficacy test: Kunming mice were divided into 3 groups: blank control group, model control group, and drug group, and injected with 2% CCL 4 Oil solution and thiosulfamide (TAA) were used to prepare the acute chemical liver injury model in mice, and the concentration of 1 gram of crude drug / ...
example 2
[0013] Example 2: Take 7 kinds of Chinese herbal medicines including 25 grams of Desmodium, 25 grams of Tianjihuang, 20 grams of bamboo leaves, 30 grams of Imperata rhizome, 40 grams of Goosegrass, 18 grams of plantain core and 35 grams of hexagonal root, and grind and sieve them respectively. Mix, add 7 times of distilled water (w / v), boil and simmer for 120 minutes, filter and add 3 times of boiling distilled water, boil and simmer for about 80 minutes, then filter, combine the filtrate, concentrate the filtrate to 150 ml with a rotary evaporator, add The starch is made into agglomerates and sieved into strips, dried at 60°C and sieved again to make granular preparations.
[0014] Preparation curative effect test: Kunming mice were divided into three groups: blank control group, model control group and drug group, and 5×10 Bacillus Calmette-Guerin (BCG) was given to the mice iv. 6 Bacteria / mouse, after 11 days, iv lipopolysaccharide (LPS) 7.5 μg / mouse, to prepare the immune ...
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