Process for producing taurine drying and sterilizing by microwave and high-efficiency ebullition

Abstract

A processing technology for producing taurine through microwave and high-performance boiling combined dry sterilization comprises addition, adjustment, synthesis, flash evaporation, pre-steaming, evaporation, neutralization and crystallization, filtration, purification, decolorization, fine filtration, centrifugation, drying, crushing and finished product packaging. The processing technology is characterized in that the processing technology comprises the following steps: the centrifugal wet high-quality product enters into a tunnel microwave drying machine for microwave drying sterilization, wherein, the temperature is controlled to 80-100 DEG C, while the time is controlled to 3-8 minutes; the product then enters into an efficient boiling machine for dry sterilization, with the temperature at 110-130 DEG C and the drying time for 1-1.5 hours. If the drying time for the efficient boiling dry sterilization is shorted, the direct use of efficient boiling sterilization drying time is around 1 hour and 40 minutes. If microwave drying followed by high-performance boiling drying, only one hour is enough. The processing technology has the advantages that the efficient boiling drying sterilization adopts pasteurization; a better effect can be achieved by cross-sterilization through microwave sterilization and efficient boiling drying sterilization. The material has slight caking through microwave, while the caking can be completely broken after efficient boiling drying sterilization to reduce the loss of the materials in the late stage.

Description

technical field [0001] The invention relates to the field of pharmaceutical processing technology. Specifically relate to the processing technique of taurine. Background technique [0002] Taurine is also called α-aminoethanesulfonic acid. The earliest production of taurine was extracted from bezoar by the extraction method, and the raw materials for this method were extremely rare. The current production process of taurine is chemical synthesis method, mainly ethylene oxide method. The process is: add ethylene oxide, sulfur dioxide, caustic soda, soda ash, liquid ammonia, sulfuric acid, etc. Addition, adjustment and synthesis reactions are carried out in the process, followed by flash evaporation, pre-steaming, evaporation, neutralization and crystallization, pressure filtration, purification, decolorization, fine filtration, centrifugation, drying, crushing, and finally packaged into finished products. The drying process mainly includes: 1. Oven drying and sterilization...

AI Technical Summary

Problems solved by technology

The advantage of this equipment is that it can guarantee the crystal form to the greatest extent, the production is stable, and there are few affected factors, but this method is labor-intensive and the equipment efficiency is low; 2. Fluidized bed drying and sterilization; adopting fluidized bed drying, The drying time of this method is short, the damage of the crystal form is small, and the water after drying is less, but it is greatly affected by the feed rate and steam pressure, the energy consumption is high, and the loss of materials is large. The biggest problem is that the dried product produced by this method is The quality of the product is unstable and the sterilization effect is poor; 3. Spray granulation drying and sterilization, this method has a large investment, but it is a complete failure in principle and practical application effect. The main problem is that the expanded taurine cannot be guaranteed. The strength of the particles, after being squeezed by their own weight, will become a powder, which is more likely to agglomerate and cannot be cooled quickly in a high temperature state; the oven drying that was added later has been proved by production to be labor-intensive, low-yield, and not suitable for large-scale production. large-scale industrial production

4. High-efficiency boiling drying sterilization method; using GFG high-efficiency boiling dry machine for drying, this method occupies a small area, high drying efficiency, low labor intensity, stable quality, very easy to achieve large-scale sterilization, the effect is also very good, the main disadvantage of this method is that due to the use of traditional bus damp heat After the bacteria method, the drying time is longer. Generally, a single batch of 500-600KG materials is dried, sterilized, and cooled in three stages of about 1.5-2 hours. A large number of collisions with the equipment cause large-scale fragmentation of the crystal form, resulting in small crystal forms, many powders, and easy agglomeration in the later stage. This shortcoming is the most prominent during long-distance transportation, causing serious problems such as agglomeration in a large area