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Antimicrobial and antiphlogistic composition and use thereof

An antibacterial and anti-inflammatory composition technology, which is applied in the field of antibacterial and anti-inflammatory compositions, and can solve the problems of small adverse reactions

Inactive Publication Date: 2009-07-22
TIANSHENG PHARMA GROUP
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although there are many kinds of antibacterial and anti-inflammatory compositions on the market, the effect of extracting from natural plants is remarkable, and there are relatively few antibacterial and anti-inflammatory compositions for external use with little adverse reactions. Good antibacterial and anti-inflammatory compositions without toxic side effects have not been reported yet.

Method used

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  • Antimicrobial and antiphlogistic composition and use thereof
  • Antimicrobial and antiphlogistic composition and use thereof
  • Antimicrobial and antiphlogistic composition and use thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0040] Embodiment 1: An antibacterial and anti-inflammatory composition is characterized in that it is mainly made from natural peach leaves and natural pomelo leaves; wherein the amount of the above-mentioned peach leaves is 1 part by weight, and the amount of pomelo leaves is 1 part by weight.

[0041] The above peach leaf extract is obtained by extracting and purifying peach leaves with ethanol; the above pomelo leaf extract is the pomelo leaf volatile oil obtained by distillation and extraction of pomelo leaves.

[0042] The above steps of extracting and purifying peach leaves with ethanol:

[0043] a. First, wash the peach leaves, extract twice with 95% ethanol under reflux, each extraction time is 2 hours, then filter, combine the filtrates and concentrate until the ratio of the weight of the filtrate to the weight of the peach leaves is 1: 2.

[0044] b. Then add water equivalent to 5 times the amount of the above concentrate, let it stand for 24 hours, and filter;

...

Embodiment 2~6

[0050] Embodiment 2~6: wherein the consumption ratio of used peach leaf and pomelo leaf is shown in Table 6, and all the other are with embodiment 1.

[0051] The consumption proportion of peach leaf and pomelo leaf used in the table 6 embodiment 2~6

[0052] Group ratio Example 2 Example 3 Example 4 Example 5 Example 6 peach leaves 1 2 3 4 5 pomelo leaf 2 3 4 5 3

Embodiment 7

[0053] Example 7: pharmaceutical preparation for external use, a base made of stearic acid 110g, potassium carbonate 10g, glyceryl monostearate 25g, triethanolamine 3ml, glycerin 100g, water 700ml, heated to 70°C, added to the combination of the present invention 50g of the substance, mix well, and get it. For external use, apply to the affected area 2-3 times a day, it has antibacterial, anti-inflammatory and antipruritic effects. It can be used for various skin diseases such as various dermatitis, itchy skin, redness and swelling of mosquito bites and bugs.

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Abstract

The invention provides an antibacterial anti-inflammation composition, which is characterized in that the composition is mainly prepared from raw materials of natural peach leaf and natural shaddock leaf, wherein the dosage of the peach leaf is between 1 and 5 weight portions, and the dosage of the shaddock leaf is between 1 and 5 weight portions. The invention also provides application of the composition as an external medicine or as an additive for lotion, bath foam and toothpaste. The composition can kill various bacteria, and the impurities in the composition are removed after purification, thus the composition almost does not have acrimony to a vagina and the skin, and is particularly suitable for sterilizing and relieving itching in an oral cavity, the vagina and the skin.

Description

technical field [0001] The invention relates to an antibacterial and anti-inflammatory composition and its application. Background technique [0002] Peach leaves are the leaves of Prunus persica (L) Batsch or P. davidiana (Carr.) Franch., a plant of the Rosaceae family. Peach leaves contain glycosides, naringenin, quinic acid, tomato hydrocarbons, tannins, and almond folate amide and a small amount of cyanoside. Clinical reports include 1. hydrocyanic acid can be released after hydrolysis of peach leaves, and the extract of peach leaves can kill a variety of mosquito larvae "larvae". 2. Take fresh peach leaves and decoct them to treat malaria. 3. Peach leaf extract treats boils and chronic urticaria. 4. Reduce swelling and relieve pain, facilitate stool. Experiments have shown that peach leaf extract has inhibitory effect on Staphylococcus aureus, Escherichia coli, Candida albicans and other pathogenic bacteria, can kill Trichomonas vaginalis, has no irritation to skin a...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/752A61K8/97A61P17/02A61Q11/00A61Q19/10
Inventor 李天泉刘群谈宗华
Owner TIANSHENG PHARMA GROUP