Medical prescription and preparation method of catalpol-puerarin freeze-dried powder injection

Abstract

The invention relates to a medical prescription and a preparation method of catalpol-puerarin freeze-dried powder injection. The invention is characterized in that the medical prescription of the catalpol-puerarin freeze-dried powder injection comprises 1 to 1000mg of catalpol, 1 to 3000mg of puerarin, 100 to 8000mg of mannite, 50 to 4000mg of fucose as well as proper amount of 50% propanediol. The freeze-dried powder injection prepared by catalpol and puerarin has medical application in the treatment of clinic cerebral ischemic diseases. The invention also comprises the adjuvant used in the medical prescription for preparing the freeze-dried powder injection of the composition prepared by catalpol, puerarin and other drugs according to different mixture ratio to cure the ischemic diseases. The invention aims at providing the compound drug preparation of the active components of Chinese herbs for curing the ischemic diseases. The preparation can penetrate blood brain barriers, lighten the injury degree of cerebral ischemia, improve the durable capacity of ischemia and oxygen deficiency of brain tissues, promote the rebirthing and maturity of brain microvascular, protect the neurovascular units, promote the growth of neuron axon and neurodendrite, enhance the synaptic reorganization, improve the neurological behavior after cerebral ischemia, increase the neurological scores and promote the motor function resuming of the tired limbs after the cerebral ischemia.

Description

technical field [0001] The invention relates to the fields of traditional Chinese medicine pharmacology and traditional Chinese medicine preparations. It specifically relates to the prescription and preparation method of the freeze-dried powder injection of the active ingredient catalpol and the active ingredient pueraria root of the traditional Chinese medicine rehmannia glutinosa, which can be used clinically to treat cerebral ischemic brain diseases. Background technique [0002] Cerebrovascular disease is one of the three major causes of death that seriously endanger human health. In my country, more people die from cerebrovascular disease than heart disease and cancer, ranking first among the three major causes of death. It has the characteristics of high morbidity, disability and mortality. It is a common disease that threatens the health of human beings, especially middle-aged and elderly people. frequently-occurring disease. Among them, ischemic cerebrovascular dise...

AI Technical Summary

Problems solved by technology

However, the therapeutic targets of these drugs are single, and the side effects are relatively large, so it is difficult to achieve satisfactory results.