Preparation method of recombination human thymosin beta 16

A thymosin and recombinant protein technology, applied in the field of bioengineering, can solve the problems of environmental pollution and high cost, and achieve the effects of broad application prospects, long duration of action, and simple structure
CN101602803AInactive Publication Date: 2009-12-16FILLDERM (CHANGCHUN) MEDICINE BIOLOGY TECH CO LTD
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Patent Information

Authority / Receiving Office
CN · China
Current Assignee / Owner
FILLDERM (CHANGCHUN) MEDICINE BIOLOGY TECH CO LTD
Publication Date
2009-12-16
Estimated Expiration
Not applicable · inactive patent

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Abstract

The invention relates to a preparation method of recombination human thymosin beta 16, belonging to the field of biological engineering. The invention aims at adopting a genetic engineering technology to prepare the recombination human thymosin beta 16. The recombination human thymosin beta 16 has an amino acid sequence: SEQ ID NO: 1. The T beta 16 is used as one of thymosin family members, has a wound healing promoting function different from the same-effect medicines applied to a market or in a developing process. The T beta 16 is not a growth factor. Compared with various growth factors, the T beta 16 has multiple advantages for healing wounds.
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Description

Technical field:

[0001] The invention belongs to the field of biological engineering. Background technique:

[0002] Thymosin is a general term for a family of polypeptides that widely exist in humans and animals. These small molecular polypeptides are composed of 40-45 amino acids, and the sequences among family members are highly conserved. Most of them have a molecular weight of about 5kDa, and they are a kind of polar polypeptide molecules.

[0003] Thymosin can be divided into α-type, β-type and γ-type according to the isoelectric point difference of family members. Among them, due to their important roles in various physiological and biochemical processes, the functions and mechanisms of β-type family members have gradually become one of the research hotspots in recent years. Thymosin β4 chemically synthesized abroad has entered phase II clinical application in corneal repair, skin burns, and ulcer repair. However, the chemical synthesis method is costly and easy to...

Claims

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