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Fomesafen soluble solid medicament form

A technology of fomesafen and solid dosage forms, applied in the field of soluble solid dosage forms, can solve problems such as increased production and transportation costs, waste of resources, environmental pollution, etc., achieve good economic benefits and environmental protection values, and reduce production and storage and transportation costs , The effect of reducing the amount of packaging materials used

Inactive Publication Date: 2010-06-02
QINGDAO YIBAI AGROCHEM TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] The main formulations of fomesafen currently on the market are 18%, 25%, 250g / L liquid and 10%, 12.8%, 20% emulsifiable concentrate. The content of active ingredients in these two formulations is generally low, and most of the ingredients in the formulation are Organic solvents or water increase production and transportation costs, especially for emulsifiable concentrate formulations, because the solubility of fomesafen technical in conventional organic solvents is small. In order to make products, special solvents or fomesafen are generally used. Ether raw medicine is salted, and the salt-forming process is relatively complicated, so processing it into emulsifiable concentrate is easy to cause environmental pollution, waste resources, and increase costs. Therefore, seeking a more environmentally friendly and economical formulation of fomesafen has become a challenge for my country's pesticide industry. important topic

Method used

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  • Fomesafen soluble solid medicament form

Examples

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Effect test

example 1

[0024] Formula: 95% fomesafen powder 20%

[0025] Sodium Hydroxide 3%

[0026] Sodium Lignin Naphthalene Sulfonate 3%

[0027] Polyoxyethylene triglyceride 6%

[0028] Silica 10%

[0029] Sodium sulfate top up 100%

[0030] Production Method:

[0031] First, the original fomesafen powder and sodium hydroxide that has been crushed to 98% and over 100 mesh, additives and fillers are added to the mixer according to the formula (if the additives are in liquid state, they can be adsorbed with white carbon black first), and mixed evenly It is made into powder or granule, packaged, put into water, stirred and dissolved before use.

example 2

[0033] Formula: 95% fomesafen powder 80%

[0034] Sodium Hydroxide 10%

[0035] Polymer Carboxylate 5%

[0036] Silica Top Up 100%

[0037] First, the original fomesafen powder and sodium hydroxide that has been crushed to 98% and over 100 mesh, additives and fillers are added to the mixer according to the formula (if the additives are in liquid state, they can be adsorbed with white carbon black first), and mixed evenly It is made into powder or granule, packaged, put into water, stirred and dissolved before use.

example 3

[0039] Formula: 95% fomesafen powder 50%

[0040] Sodium Hydroxide 6%

[0041] Naphthalene sulfonate formaldehyde condensate 5%

[0042] Polyethylene oxide propylene oxide ether 15%

[0043] Silica 10%

[0044] Sodium sulfate top up 100%

[0045] First, the original fomesafen powder and sodium hydroxide that has been crushed to 98% and over 100 mesh, additives and fillers are added to the mixer according to the formula (if the additives are in liquid state, they can be adsorbed with white carbon black first), and mixed evenly It is made into powder or granule, packaged, put into water, stirred and dissolved before use.

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Abstract

The invention relates to a fomesafen water-soluble solid medicament form which aims to provide a fomesafen solid medicament form. The fomesafen water-soluble solid medicament form is characterized by being prepared from following components in mass ratio: 10-90% of fomesafen, 2-50% of sodium hydroxide, 0-30% of surfactant and the balance of filler which is added to complement 100%. The fomesafen water-soluble solid medicament form is prepared by mixing the components evenly to prepare powder or granules and packaging. When the fomesafen water-soluble solid medicament form is used, the fomesafen water-soluble solid medicament form is put into water and used after stirring and dissolving. The product furthest enhances the content of effective components and controls the use of an organic solvent and the water, thereby lowering the production and transportation cost and lightening the environmental pollution.

Description

technical field [0001] The invention relates to a herbicide used in agriculture, in particular to a soluble solid dosage form with the original medicine of fomesafen as the main component. technical background [0002] Fomesafen is a fluorine-containing diphenyl ether selective herbicide for dry fields, the English generic name is fomesafen, the foreign product trade name is Huwei, and the chemical name is 5-[2-chloro-4-(trifluoromethyl)phenoxy]- N-methylsulfonyl-2-nitrobenzamide, the structural formula is: [0003] [0004] Fomesafen has high fat solubility and hydrophobicity, and has good permeability to cells and tissues. It is a highly selective post-emergence herbicide. It is mainly used for the control of broad-leaved weeds in legume crop fields. It is absorbed by the roots and leaves of weeds, causing it to quickly turn yellow and die. It will not affect the efficacy of the drug when exposed to rain 4-6 hours after spraying. [0005] At present, the main dosage f...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A01N41/06A01N25/12A01N25/34A01P13/00
Inventor 乔恩刚孙作洋
Owner QINGDAO YIBAI AGROCHEM TECH
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