Application of pubescent pepper herb extract in preparing medicine for treating or preventing acute and chronic liver injury

Abstract

The invention discloses application of a pubescent pepper herb extract in preparing a medicine for treating or preventing acute and chronic liver injury. In the invention, the pubescent pepper herb extract is used in the medicine for treating or preventing the acute and chronic liver injury, and a series of pharmacological effect tests fully prove the curative effect of pubescent pepper herb in treating or preventing the acute and chronic liver injury. The invention has the advantages of wide material source, low cost, small side effects and the like.

Description

technical field [0001] The invention relates to the field of pharmacy, in particular to the application of a betel extract in the preparation of medicines for treating or preventing acute and chronic liver injuries. Background technique [0002] Liver disease is a type of disease that seriously endangers human health, with a high incidence rate, including viral hepatitis, liver cirrhosis, fatty liver, alcoholic liver, drug-induced liver disease, genetic liver disease, etc. liver injury, especially acute liver injury. At present, there is no uniform definition of acute liver injury. In a broad sense, abnormal liver function indicators due to any cause are indicative of liver injury (acute liver injury may be considered if ALT and AST are higher than normal limits, as recommended by the American National Clinical Association). The common causes of acute liver injury are: 1. Infection: various types of hepatitis viruses are common, followed by non-hepatitis viruses; 2. Drug po...

AI Technical Summary

Problems solved by technology

At present, the treatment for liver damage is mainly drug therapy. The traditional common liver protection drugs include potassium magnesium aspartate, reduced glutathione, tiopronin, diamine glycyrrhizinate, etc. The mechanism of liver protection is related to anti-inflammation, protection Liver cell membrane and metabolism are related. In the use of the above drugs, there are large individual differences. After use, some patients may experience gastrointestinal adverse reactions such as blood pressure changes, abdominal distension, rash, fever, nausea, and vomiting.

With the use of some new anti-viruses, immunomodulators, and cytokines, the treatment of liver diseases has developed to a certain extent in recent years, but there are still problems such as high price, large individual differences, and allergies, which limit its application in clinical liver disease treatment

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