Technological process for extracting aucubin from fruits of eucommia ulmoides oliver

A kind of aucubinin and process method technology, applied in the directions of chemical instruments and methods, pharmaceutical formulations, non-central pain relievers, etc., can solve the problems such as insufficient utilization of Eucommia ulmoides, unfavorable large-scale production operations, cumbersome preparation process, etc. Easy to scale up for industrialization, low cost, good purity
CN101982471AInactive Publication Date: 2011-03-02TIANJIN UNIVERSITY OF TECHNOLOGY
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
TIANJIN UNIVERSITY OF TECHNOLOGY
Publication Date
2011-03-02
Estimated Expiration
Not applicable · inactive patent

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Abstract

The invention relates to a technological process for extracting aucubin from fruits of eucommia ulmoides oliver, which comprises the following steps: cutting the fruits of the eucommia ulmoides oliver into pieces, extracting with water or ethanol solution as an extraction solvent, and purifying the obtained extracting solution with macroporous resin to obtain the aucubin the purity of which is more than 50%. The technological process has the advantages of low toxicity, safety, short process time, no environmental pollution, simple and convenient operation, easy industrialization enlargement, high yield and good purity of the product, thus meeting various needs for development of drugs taking the fruits of the eucommia ulmoides oliver as main raw materials.
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Description

【Technical field】

[0001] The invention relates to a method for extracting and separating effective plant components in the pharmaceutical industry, in particular to a process for extracting aucubin from Eucommia ulmoides. 【Background technique】

[0002] Aucubin (aucubin) belongs to iridoid glycosides with molecular formula C 15 h 22 o 9 , molecular weight 346.331, CAS No. 479-98-1, melting point 181°C, easily soluble in water, ethanol and methanol, almost insoluble in chloroform, ether and petroleum ether. This compound mainly exists in plants such as Eucommia ulmoides Oliver, Aucubachinensis Benth., Plantago asiatica L., etc. Liver protection and detoxification, anti-inflammatory, anti-oxidation, anti-aging, anti-osteoporosis and nutrition neuron cells and many other pharmacological activities. The structural formula of aucubin is as follows:

[0003]

[0004] Eucommia ulmoides is the fruit of Eucommia ulmoides Oliver, a single species of Eucommia ulmoides Oliver in...

Claims

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