Biomimetic modification method of controllable titanium dioxide nano-tube on surface of titanium planting body and planting body

A titanium implant and titanium dioxide technology, applied in the field of medical nano-bionic materials preparation, can solve the problems of ineffective selection of microstructure and poor controllability, and achieve the effect of promoting adhesion growth

Inactive Publication Date: 2012-03-21
SHANGHAI NINTH PEOPLES HOSPITAL AFFILIATED TO SHANGHAI JIAO TONG UNIV SCHOOL OF MEDICINE
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

In recent years, with the development of nanotechnology and bionic technology, scholars have begun to perform nano-modification on the ...

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  • Biomimetic modification method of controllable titanium dioxide nano-tube on surface of titanium planting body and planting body
  • Biomimetic modification method of controllable titanium dioxide nano-tube on surface of titanium planting body and planting body

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Embodiment Construction

[0017] Next, a method for biomimetic modification of a titanium surface controllable titanium dioxide nanotube and a specific implementation of the modified implant described in the present invention will be described in detail with reference to the accompanying drawings.

[0018] attached figure 1 Shown is a schematic diagram of the steps of the method described in this specific embodiment, including: step S10, providing a titanium implant to be modified; step S11, cleaning the surface of the titanium implant; step S12, removing the natural oxide film on the surface of the titanium implant; Step S13, placing the titanium implant on the anode of the electrolytic cell for anodic oxidation; step S14, using sodium hydroxide solution to perform alkali treatment on the titanium implant surface-modified with titanium dioxide nanotubes; step S15, heat-treating the titanium implant in air ; Step S16, placing the treated titanium implant in a centrifuge tube filled with simulated body ...

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Abstract

The invention relates to a biomimetic modification method of a controllable titanium dioxide nano-tube on a surface of a planting body, which comprises the following steps that: a titanium planting body to be modified is provided; the surface of the titanium planting body is washed; a natural oxidized film on the surface of the titanium planting body is removed; the titanium planting body is arranged on anode of an electrolytic cell to be oxidized to obtain a titanium dioxide nano-tube structure; sodium hydroxide solution is adopted for the alkaline treatment of the titanium planting body with the surface being modified by the titanium dioxide nano-tube; heat treatment on the titanium planting body is undertaken in the air; the titanium planting body after being treated is placed into a centrifugal pipe with simulation body liquid to incubate; and the titanium planting body is de-ionized, washed and dried. The biomimetic modification method has the advantages that: a unique structure of the titanium dioxide (TiO2) nano-tube is used for building a biomimetic nano calcium-phosphous coating on the surface of the planting body, after the planting body is planted into a human body, on the one hand, the planting body is in a nano-grade structure and can provide contact for osteoplast byssus to promote the adhesion growth of cells, and on the other hand, the calcium-phosphous coating is consistent with inorganic composition of natural bone, so an osteoacusis characteristic can be realized.

Description

【Technical field】 [0001] The invention relates to the field of preparation of medical nano-bionic materials, in particular to a controllable bionic modification method of titanium dioxide nanotubes on the surface of a titanium implant. 【Background technique】 [0002] Dental implant technologies such as implant dentures are more and more favored by doctors and patients because of their comfortable appearance, good masticatory function recovery and ability to avoid or reduce the grinding of natural teeth. However, most of the implant systems commonly used in clinical practice are poor in performance and expensive, and there is no implant system with good performance recognized by everyone. Therefore, planting materials have always been a research hotspot for material experts. [0003] Implant surface topography and chemical composition play a very important role in the bone healing of implants in vivo, that is, "osseointegration". Scholars often improve the effect of "osseoi...

Claims

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Application Information

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IPC IPC(8): C25D11/26A61L27/30
Inventor 于卫强张富强
Owner SHANGHAI NINTH PEOPLES HOSPITAL AFFILIATED TO SHANGHAI JIAO TONG UNIV SCHOOL OF MEDICINE
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