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Room temperature preparation method for ultrafine huoxiang zhengqi powder, and special bidirectional air flow screening device

A technology of Huoxiang powder and Zhengqi powder, which is applied in powder delivery, pharmaceutical formulations, medical preparations containing active ingredients, etc., can solve the problems of difficulty in precise control of the maximum particle size of drugs, inability to produce continuously, and low clinical dosage, etc. Achieve the effect of being suitable for large-scale industrial production, saving medicinal materials, improving cell wall breaking rate and bioavailability

Active Publication Date: 2013-08-28
HENAN KANGXING PHARMA
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AI Technical Summary

Problems solved by technology

[0004] The purpose of the present invention is to provide a method for preparing ultrafine powder Huoxiangzhengqi Powder at normal temperature, which effectively solves the problems of high energy consumption, difficulty in precise control of the maximum particle size of the drug, inability to continuously produce, and much dust in the production process, which exist in the current production. The prepared finished medicine has the effects of fast onset of action, good curative effect, high bioavailability, and less clinical dosage

Method used

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  • Room temperature preparation method for ultrafine huoxiang zhengqi powder, and special bidirectional air flow screening device
  • Room temperature preparation method for ultrafine huoxiang zhengqi powder, and special bidirectional air flow screening device

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Embodiment Construction

[0028] Such as figure 1 , 2 Shown, the normal temperature preparation method of superfine powder Huoxiangzhengqi powder of the present invention comprises the following steps:

[0029] The first step is to select raw materials such as patchouli, perilla leaves, poria cocos, angelica dahurica, big belly skin, tangerine peel, bellflower, Atractylodes macrocephala (stir-fried), magnolia officinalis, pinellia chinensis, and licorice slices; wash, dry or bake Dry to moisture content ≤ 10%;

[0030] The second step is to pulverize the above raw materials respectively at a temperature of 20°C to 25°C to obtain a coarse powder with a particle size of 60 to 120 mesh;

[0031] The third step, press the coarse powder obtained in the second step according to patchouli: Perilla leaf: Poria cocos: Angelica dahurica: Big belly skin: Tangerine peel: Campanulaceae: Atractylodes macrocephala (stir-fried): Magnolia officinalis: Fa Pinellia: Licorice = 12:9: The weight ratio of 6:3:6:6:5:6:6:...

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Abstract

The present invention discloses a room temperature preparation method for ultrafine huoxiang zhengqi powder. The preparation method comprises: selecting raw drugs of cablin potchouli herb, cultivated purple perilla leaf, tuckahoe, angelica archang lica, pericarpium arecae, tangerine peel, balloonflower root, largehead atractylodes rhizome, officinal magnolia bark, prepared pinellia tuber and licorice root; cleaning and drying; respectively crushing the raw drugs at a room temperature to obtain crude powders with the particle size of 60-120 meshes; uniformly mixing the resulting crude powders according to a certain ratio, and placing the resulting crude powder mixture in a rod mill to carry out crushing; conveying the resulting material to a special bidirectional air flow screening device with air, carrying out screening by a sieve having 500 meshes to obtain the powder material with the particle size less than or equal to 25 micrometers; conveying the powder material to a cyclone material collecting device by the air flow generated by a draft fan to carry out collecting, wherein the partial powder material does not pass through the sieve having 500 meshes, and is collected by a hopper and conveyed to the rod mill by a pipeline to carry out cycling crushing again. The method of the present invention has the following advantages that: the whole preparation process is performed at the room temperature, the particle size of the prepared finished drug is less than or equal to 25 micrometers, and the cell wall breaking rate and the bioavailability are substantially improved. With the special bidirectional air flow screening device of the present invention, the preparation process for the ultrafine huoxiang zhengqi powder is simplified.

Description

technical field [0001] The invention relates to the field of veterinary drug preparations, in particular to a method for preparing superfine powder Huoxiangzhengqi powder at normal temperature; the invention also relates to a special two-way airflow sieving machine used in the method. Background technique [0002] Huoxiangzhengqi Powder, which is currently used in the prevention and treatment of livestock diseases in summer, mainly consists of powders composed of more than ten traditional Chinese medicines such as Huoxiang, perilla leaves, and Angelica dahurica. , Relieve intestinal smoothness and spasm, have obvious inhibitory effect on Staphylococcus aureus, type A and B paratyphi, and Shigella. The existing powders have the disadvantages of large dose, rough dosage form, poor appearance, insufficient release of active ingredients, and low bioavailability, which have seriously affected the quality and therapeutic effect of traditional Chinese medicines. [0003] Tradition...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/8888A61K9/14B02C23/20A61P1/12A61P31/04
Inventor 刘瑞丽王伟伟张国祖宋永奇王巧红
Owner HENAN KANGXING PHARMA
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