Chinese medicinal composition for treating chronic gastric ulcer

A chronic gastric ulcer and composition technology, applied in the field of traditional Chinese medicine composition for the treatment of chronic gastric ulcer, can solve problems such as ineffective effects, large toxic and side effects, liver and kidney damage, etc., achieve good therapeutic effect, safe medication, and good curative effect Effect

Active Publication Date: 2012-07-11
JIANGSU ZODIAC MARINE BIOTECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] At present, there are many kinds of western medicines for treating gastric ulcer on the market, such as cimetidine, ranitidine, famotidine, etc. These medicines have remarkable effects in treating gastric ulcer, but they have too many side effects, damage the liver and kidney, and H2 is affected. Body blockers have different degrees of dizziness, drowsiness, abdominal pain, nausea and other adverse reactions
Although there are many Chinese patent medicines, most of them take too long to relieve pain and the effect is not obvious

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0038] Herbal medicine prescription: 8 parts of Baiji, 15 parts of Angelica dahurica, 5 parts of Gansong, 15 parts of Agrimony, 12 parts of betel nut, 8 parts of Angelica, 8 parts of Yuanhu, 12 parts of Xu Changqing, 8 parts of amomum, 20 parts of Chinese yam, 6 parts of Coptis chinensis 8 parts, 8 parts of psoralen.

[0039] Preparation method: Weigh and combine the above-mentioned medicinal materials, add water to decoct twice, add water for the first time to 10 times the weight of the medicinal materials, decoct for 2 hours, add water for the second time to 8 times the weight of the medicinal materials, and decoct for 1.5 hours , combined decoction, 0.08MPa, concentrated under reduced pressure at 65°C to a relative density of 1.15 at 65°C, added 95% (v / v) ethanol to make the alcohol content reach 85% (v / v), stirred, and stood overnight , filtered, and the filtrate was concentrated under reduced pressure at 0.08MPa and 65°C to a relative density of 1.30 at 65°C, and was prep...

Embodiment 2

[0041] Herbal medicine prescription: 10 parts of Baiji, 18 parts of Angelica dahurica, 5 parts of Gansong, 12 parts of Agrimony, 10 parts of betel nut, 10 parts of angelica, 10 parts of Yuanhu, 10 parts of Xu Changqing, 6 parts of amomum, 25 parts of yam, 6 parts of coptis 10 parts, 10 parts of psoralen.

[0042] Preparation:

[0043] The first step, prepare clear cream powder:

[0044] 1) Material preparation: Weigh the above-mentioned Chinese medicinal materials cleaned according to the prescription amount, and set aside;

[0045] 2) Decoction: add water to decoct, add water to each pot of the first decoction to be 6 times the total amount of medicinal materials, heat and boil for 4 hours, the extract is filtered through a 200-mesh filter and enter the sedimentation tank; the second decoction adds 6 times the amount of medicinal materials The water is heated and extracted, kept boiling for 4 hours, and the extract is filtered through a 200-mesh filter and enters the sediment...

Embodiment 3

[0052] Embodiment 3 The influence of traditional Chinese medicine composition of the present invention on rats with chronic gastric ulcer

[0053] Ten SD rats were randomly selected as the blank group. After ether anesthesia, a 1.5 cm incision was made under the xiphoid process through the midline of the abdominal wall, and the stomach was sutured for sham operation after the stomach was exposed; Press the cylinder on the serosa surface of the anterior gastric wall about 5mm below the lesser curvature notch, inject 0.25m1 of 99.9% acetic acid into the cylinder, absorb the acetic acid with filter paper after 1 min, remove the cylinder, and add normal saline Partial flushing, the greater omentum wrapped the eroded gastric wall, and the gastric body was sutured layer by layer. Routine anti-infection for 3 days after operation, 48 surviving model rats were selected 5 days later, and randomly divided into model control group, traditional Chinese medicine low-dose and high-dose grou...

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PUM

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Abstract

The invention discloses a Chinese medicinal composition for treating chronic gastric ulcer, which relates to the technical field of traditional Chinese medicines. The Chinese medicinal composition is prepared from the following Chinese medicinal materials in parts by weight: 8-12 parts of common bletilla pseudobulb, 15-20 parts of dahurian angelica root, 3-6 parts of nardostachyos root and rhizome, 10-15 parts of hairyvein agrimonia herb and bud, 8-12 parts of areca nut, 8-12 parts of Chinese angelica, 8-12 parts of rhizoma corydalis, 8-12 parts of paniculate swallowwort root, 4-8 parts of amomum fruit, 20-30 parts of Chinese yam, 4-8 parts of coptis root and 8-12 parts of malaytea scurfpea fruit. The Chinese medicinal composition related to the invention has a remarkable curative effect on chronic gastric ulcer, can be used for tonifying spleen, regulating qi, dissipating swelling and relieving pain, and has high safety.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine, in particular to a traditional Chinese medicine composition for treating chronic gastric ulcer. Background technique [0002] Gastric ulcer is a common and frequently-occurring disease of the digestive system. The more obvious causes are Helicobacter pylori infection, taking non-steroidal anti-inflammatory drugs (NSATD) and excessive gastric acid secretion; in addition, it can also be caused by genetic factors and mood swings, overwork, eating disorders, smoking, alcoholism and other factors. Gastric ulcer is a long-lasting, complex condition, and related to mental and emotional conditions. If the condition is exacerbated or not treated in time, it will also lead to gastric bleeding, gastric perforation, pyloric obstruction, and cancer. It seriously endangers people's health, so it should be highly valued. . Gastric ulcers in traditional Chinese medicine belong to the categ...

Claims

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Application Information

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IPC IPC(8): A61K36/9064A61P1/04
Inventor 韩善文高娜
Owner JIANGSU ZODIAC MARINE BIOTECH
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