Scutellarin aglycone methylate product based on in-vivo metabolic mechanism as well as preparation method and application of scutellarin aglycone methylate product

A technology of scutellarin aglycon methyl and scutellarin aglycone, which is applied in the field of medicinal chemistry research and can solve the problem of low adverse reactions
CN102702155AInactive Publication Date: 2012-10-03NANJING UNIVERSITY OF TRADITIONAL CHINESE MEDICINE
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Patent Information

Authority / Receiving Office
CN · China
Current Assignee / Owner
NANJING UNIVERSITY OF TRADITIONAL CHINESE MEDICINE
Publication Date
2012-10-03
Estimated Expiration
Not applicable · inactive patent

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Abstract

The invention relates to the field of pharmaceutical chemistry study, in particular to a novel scutellarin aglycone methylate product based on in-vivo metabolic mechanism as well as a preparation method of the novel scutellarin aglycone methylate product and an application of the novel scutellarin aglycone methylate product to thrombus prevention and treatment medicine. Pharmacological experiment results show that the scutellarin aglycone methylate product provided by the invention has pharmacological effects of better solubility, antioxidation, cell damage inhabitation and the like, and can be developed into novel medicine for preventing and treating thrombotic diseases.
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Description

technical field

[0001] The invention relates to the field of medicinal chemistry research, in particular to a new type of scutellarin aglycone methylation product based on in vivo metabolism mechanism, its preparation method and its application in anti-thrombotic drugs. Background technique

[0002] Scutellaria scutellarin is a flavonoid compound in breviscapus breviscapus, a plant of the family Asteraceae. Erigeron breviscapus is also known as scutellaria breviscapus, also known as scutellaria breviscapus, soil asarum, chrysanthemum, asarum, oriental chrysanthemum, etc., scutellaria breviscapus Cold in nature, slightly bitter, sweet and warm, has the effects of dispelling cold and relieving the exterior, expelling wind and dampness, promoting blood circulation and removing blood stasis, dredging meridian and activating collaterals, reducing inflammation and relieving pain. Breviscapine is a flavonoid active ingredient extracted from the natural plant breviscapine, including...

Claims

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