Preparation method of glycyl-tyrosine

A technology of glycyl chloride hydrochloride and tyrosine, applied in the direction of peptides, etc., can solve the problems of difficulty in drug production verification, inability to industrialize production, environmental hazards, etc., achieve low cost, reduce pollution, and avoid the use of organic solvents Effect
CN103172695BActive Publication Date: 2015-03-11SICHUAN KELUN PHARMA RES INST CO LTD
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
SICHUAN KELUN PHARMA RES INST CO LTD
Publication Date
2015-03-11

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Abstract

The invention discloses a preparation method of glycyl-tyrosine. The method comprises the following steps: passing glycine through thionyl chloride to obtain glycyl chloride hydrochloride, and preparing the glycyl-tyrosine from the glycyl chloride hydrochloride and tyrosine in an aqueous solution. The method disclosed by the invention has the advantages of high yield, low cost and low environmental pollution, and is simple to operate.
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Description

technical field

[0001] The invention relates to a preparation method of chemical medicines, in particular to a preparation method of a crude drug glycyl-tyrosine, which belongs to the field of chemical medicines. Background technique

[0002] Compound amino acid dipeptide injection is an amino acid nutritional infusion, which includes two dipeptides, glycyl-glutamine (GQ) and glycyl-tyrosine (GY), which provide amino acids for parenteral nutrition An integral part of treatment for patients who cannot receive oral or enteral nutrition, and who cannot meet their needs through these routes, especially in patients with moderate to severe catabolic conditions.

[0003] Tyrosine is the precursor of catecholamine (CA) transmitter in the body, giving exogenous tyrosine can affect the synthesis and release of catecholamine in the body, and regulate the functions of various systems of the body. In recent years, it has also been found that tyrosine can affect some functions of the bod...

Claims

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