Pharmaceutical composition for treating femoral head necrosis and preparation method thereof
A technology for femoral head necrosis and composition, which is applied in the field of pharmaceutical compositions for treating femoral head necrosis and its preparation, can solve the problems of collapse and deformation of the femoral head, strong unpredictability, influence on quality of life, etc. Good therapeutic effect, good taste effect
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Embodiment 1
[0053] The preparation of embodiment 1 granule
[0054] The bulk drug of the pharmaceutical composition described in the present embodiment consists of:
[0055] Sanqi 150g, Epimedium 500g, Safflower 150g, Salvia miltiorrhiza 600g, Drynaria fortunei 500g, Dipsacus 500g, Corydalis 300g, Achyranthes bidentata 300g.
[0056] In the pharmaceutical composition bulk drug of the present invention listed above, add conventional adjuvant, according to conventional fluidized bed granulation process, make granule, specifically include:
[0057] (1) Take Panax notoginseng, Epimedium, Salvia miltiorrhiza, Dipsacus and Corydalis Corydalis according to the weight selected above and mix them, add 10 times the amount of 70% ethanol, reflux extraction twice, each time for 2 hours, filter and combine Each filtrate is concentrated under reduced pressure below 60°C until it has no alcohol smell, and the alcohol extract is obtained, which is set aside;
[0058] (2) According to the above-mentione...
Embodiment 2
[0061] The preparation of embodiment 2 granules
[0062] The bulk drug of the pharmaceutical composition described in the present embodiment consists of:
[0063] Sanqi 100g, Epimedium 650g, Safflower 300g, Salvia 1400g, Drynaria 900g, Dipsacus 300g, Corydalis 600g, Achyranthes bidentata 100g.
[0064] In the pharmaceutical composition bulk drug of the present invention listed above, add conventional adjuvant, according to conventional wet granulation process, make granule, specifically include:
[0065] (1) Take Panax notoginseng, Epimedium, Salvia miltiorrhiza, Dipsacus and Corydalis Corydalis according to the weight selected above, mix them, add 10 times the amount of 80% ethanol, reflux extraction twice, each time for 1.5 hours, filter and combine Each filtrate is concentrated under reduced pressure below 60°C until it has no alcohol smell, and the alcohol extract is obtained, which is set aside;
[0066] (2) According to the weight selected above, take safflower, Drynar...
Embodiment 3
[0069] Embodiment 3 granule preparation
[0070] The bulk drug of the pharmaceutical composition described in the present embodiment consists of:
[0071] Sanqi 100g, Epimedium 750g, Safflower 100g, Salvia 1000g, Drynaria 400g, Dipsacus 800g, Corydalis 100g, Achyranthes bidentata 550g.
[0072] In the pharmaceutical composition bulk drug of the present invention listed above, add conventional adjuvant, according to conventional process, make granule, specifically include:
[0073] (1) Take Panax notoginseng, Epimedium, Salvia miltiorrhiza, Dipsacus and Corydalis Corydalis according to the weight selected above, mix them, add 6 times the amount of 90% ethanol, reflux extraction once, each time for 2 hours, filter and combine Each filtrate is concentrated under reduced pressure below 60°C until it has no alcohol smell, and the alcohol extract is obtained, which is set aside;
[0074] (2) Take safflower, drynaria rhizome and Achyranthes bidentata three raw materials according t...
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